| Full name: ubiquitin conjugating enzyme E2 Q1 | Alias Symbol: PRO3094|NICE-5 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 55585 | HGNC ID: HGNC:15698 | Ensembl Gene: ENSG00000160714 | OMIM ID: 617429 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of UBE2Q1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2Q1 | 55585 | 217978_s_at | 0.6472 | 0.0874 | |
| GSE20347 | UBE2Q1 | 55585 | 217978_s_at | 0.1798 | 0.1766 | |
| GSE23400 | UBE2Q1 | 55585 | 217978_s_at | 0.2697 | 0.0000 | |
| GSE26886 | UBE2Q1 | 55585 | 217978_s_at | 0.3562 | 0.1563 | |
| GSE29001 | UBE2Q1 | 55585 | 217978_s_at | 0.3382 | 0.1478 | |
| GSE38129 | UBE2Q1 | 55585 | 217978_s_at | 0.4080 | 0.0002 | |
| GSE45670 | UBE2Q1 | 55585 | 217978_s_at | 0.1453 | 0.1232 | |
| GSE53622 | UBE2Q1 | 55585 | 53078 | 0.0712 | 0.4809 | |
| GSE53624 | UBE2Q1 | 55585 | 53078 | -0.0811 | 0.2109 | |
| GSE63941 | UBE2Q1 | 55585 | 217978_s_at | -0.0475 | 0.9048 | |
| GSE77861 | UBE2Q1 | 55585 | 217978_s_at | 0.5883 | 0.0045 | |
| GSE97050 | UBE2Q1 | 55585 | A_23_P97423 | -0.0619 | 0.8468 | |
| SRP007169 | UBE2Q1 | 55585 | RNAseq | -0.0871 | 0.7995 | |
| SRP008496 | UBE2Q1 | 55585 | RNAseq | 0.3329 | 0.1749 | |
| SRP064894 | UBE2Q1 | 55585 | RNAseq | 0.1323 | 0.2724 | |
| SRP133303 | UBE2Q1 | 55585 | RNAseq | 0.3487 | 0.0064 | |
| SRP159526 | UBE2Q1 | 55585 | RNAseq | 0.5796 | 0.0000 | |
| SRP193095 | UBE2Q1 | 55585 | RNAseq | 0.2115 | 0.0276 | |
| SRP219564 | UBE2Q1 | 55585 | RNAseq | 0.2120 | 0.4584 | |
| TCGA | UBE2Q1 | 55585 | RNAseq | 0.0843 | 0.0712 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UBE2Q1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2Q1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2Q1 | 55585 | 15 | 0 | 15 | |
| GSE20123 | UBE2Q1 | 55585 | 14 | 0 | 16 | |
| GSE43470 | UBE2Q1 | 55585 | 6 | 2 | 35 | |
| GSE46452 | UBE2Q1 | 55585 | 2 | 1 | 56 | |
| GSE47630 | UBE2Q1 | 55585 | 14 | 0 | 26 | |
| GSE54993 | UBE2Q1 | 55585 | 0 | 4 | 66 | |
| GSE54994 | UBE2Q1 | 55585 | 16 | 0 | 37 | |
| GSE60625 | UBE2Q1 | 55585 | 0 | 0 | 11 | |
| GSE74703 | UBE2Q1 | 55585 | 6 | 1 | 29 | |
| GSE74704 | UBE2Q1 | 55585 | 7 | 0 | 13 | |
| TCGA | UBE2Q1 | 55585 | 38 | 2 | 56 |
Total number of gains: 118; Total number of losses: 10; Total Number of normals: 360.
Somatic mutations of UBE2Q1:
Generating mutation plots.
Highly correlated genes for UBE2Q1:
Showing top 20/205 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2Q1 | ASCL2 | 0.694335 | 3 | 0 | 3 |
| UBE2Q1 | HOXD13 | 0.693973 | 3 | 0 | 3 |
| UBE2Q1 | SAPCD2 | 0.687847 | 4 | 0 | 3 |
| UBE2Q1 | KRTAP4-1 | 0.681493 | 4 | 0 | 4 |
| UBE2Q1 | GABRR1 | 0.669897 | 4 | 0 | 4 |
| UBE2Q1 | RNF44 | 0.666519 | 5 | 0 | 4 |
| UBE2Q1 | SNRPB | 0.666092 | 4 | 0 | 3 |
| UBE2Q1 | NUP210 | 0.658637 | 4 | 0 | 3 |
| UBE2Q1 | AGO2 | 0.655638 | 4 | 0 | 3 |
| UBE2Q1 | COL7A1 | 0.653353 | 4 | 0 | 3 |
| UBE2Q1 | YDJC | 0.650433 | 4 | 0 | 3 |
| UBE2Q1 | CCDC122 | 0.645534 | 3 | 0 | 3 |
| UBE2Q1 | ANKRD23 | 0.642252 | 5 | 0 | 5 |
| UBE2Q1 | PRR7 | 0.639448 | 5 | 0 | 4 |
| UBE2Q1 | HDGF | 0.638353 | 8 | 0 | 7 |
| UBE2Q1 | TRMT2A | 0.635756 | 4 | 0 | 4 |
| UBE2Q1 | PNPT1 | 0.63495 | 4 | 0 | 3 |
| UBE2Q1 | KMT2B | 0.631964 | 4 | 0 | 3 |
| UBE2Q1 | NTPCR | 0.631304 | 4 | 0 | 3 |
| UBE2Q1 | FAM83H | 0.629486 | 3 | 0 | 3 |
For details and further investigation, click here
