SNRPB

 

Full name: small nuclear ribonucleoprotein polypeptides B and B1 Alias Symbol: COD|SmB/SmB'|Sm-B/B'|snRNP-B
Type: protein-coding gene Cytoband: 20p13
Entrez ID: 6628 HGNC ID: HGNC:11153 Ensembl Gene: ENSG00000125835 OMIM ID: 182282
Drug and gene relationship at DGIdb

 

Expression of SNRPB:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SNRPB 6628 213175_s_at 0.7426 0.1033
GSE20347 SNRPB 6628 213175_s_at 0.6718 0.0001
GSE23400 SNRPB 6628 213175_s_at 0.8256 0.0000
GSE26886 SNRPB 6628 213175_s_at -0.5065 0.0573
GSE29001 SNRPB 6628 208821_at 0.6965 0.0079
GSE38129 SNRPB 6628 213175_s_at 0.9943 0.0000
GSE45670 SNRPB 6628 213175_s_at 0.5001 0.0184
GSE53622 SNRPB 6628 136895 0.7128 0.0000
GSE53624 SNRPB 6628 136895 0.6812 0.0000
GSE63941 SNRPB 6628 213175_s_at 2.4825 0.0000
GSE77861 SNRPB 6628 213175_s_at 0.7745 0.0018
GSE97050 SNRPB 6628 A_23_P154675 0.6616 0.2372
SRP007169 SNRPB 6628 RNAseq -0.4194 0.2892
SRP008496 SNRPB 6628 RNAseq -0.1686 0.4026
SRP064894 SNRPB 6628 RNAseq 0.9374 0.0009
SRP133303 SNRPB 6628 RNAseq 0.7972 0.0000
SRP159526 SNRPB 6628 RNAseq 0.9532 0.0001
SRP193095 SNRPB 6628 RNAseq 0.5229 0.0004
SRP219564 SNRPB 6628 RNAseq 0.6640 0.0593
TCGA SNRPB 6628 RNAseq 0.3253 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by SNRPB expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SNRPB:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SNRPB 6628 12 3 15
GSE20123 SNRPB 6628 13 3 14
GSE43470 SNRPB 6628 11 1 31
GSE46452 SNRPB 6628 26 1 32
GSE47630 SNRPB 6628 18 4 18
GSE54993 SNRPB 6628 2 14 54
GSE54994 SNRPB 6628 24 2 27
GSE60625 SNRPB 6628 0 0 11
GSE74703 SNRPB 6628 10 1 25
GSE74704 SNRPB 6628 8 1 11
TCGA SNRPB 6628 40 11 45

Total number of gains: 164; Total number of losses: 41; Total Number of normals: 283.  

 

Somatic mutations of SNRPB:

 

Generating mutation plots.

 

Highly correlated genes for SNRPB:

 

Showing top 20/1102 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SNRPBNOP560.777516303
SNRPBGINS10.76536211010
SNRPBPCNA0.76300912012
SNRPBAURKB0.76210611011
SNRPBILF20.76006511011
SNRPBTPX20.7569112011
SNRPBCDC25B0.74981610010
SNRPBCDK40.74817510010
SNRPBCKS1B0.73779312011
SNRPBSSRP10.73778210010
SNRPBSLC3A20.73429310010
SNRPBCDCA50.733771606
SNRPBMCM20.73265312011
SNRPBCDC450.7310811010
SNRPBEFTUD20.729766606
SNRPBMCM70.72688411011
SNRPBFAM43A0.725652303
SNRPBCDC200.72517211011
SNRPBNCAPH0.723239807
SNRPBPLK10.72261311011

For details and further investigation, click here