HDGF

 

Full name: heparin binding growth factor Alias Symbol: HMG1L2
Type: protein-coding gene Cytoband: 1q23.1
Entrez ID: 3068 HGNC ID: HGNC:4856 Ensembl Gene: ENSG00000143321 OMIM ID: 600339
Drug and gene relationship at DGIdb

 

Expression of HDGF:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 HDGF 3068 200896_x_at 0.8549 0.0250
GSE20347 HDGF 3068 200896_x_at 0.4593 0.0000
GSE23400 HDGF 3068 200896_x_at 0.5957 0.0000
GSE26886 HDGF 3068 200896_x_at 0.4709 0.0015
GSE29001 HDGF 3068 200896_x_at 0.4968 0.0061
GSE38129 HDGF 3068 200896_x_at 0.6852 0.0000
GSE45670 HDGF 3068 200896_x_at 0.4986 0.0005
GSE53622 HDGF 3068 41533 0.7999 0.0000
GSE53624 HDGF 3068 41533 0.7712 0.0000
GSE63941 HDGF 3068 200896_x_at 0.7366 0.0049
GSE77861 HDGF 3068 200896_x_at 0.6960 0.0129
GSE97050 HDGF 3068 A_24_P376707 0.8945 0.0948
SRP007169 HDGF 3068 RNAseq -0.1568 0.6529
SRP008496 HDGF 3068 RNAseq -0.0325 0.8632
SRP064894 HDGF 3068 RNAseq 0.3889 0.0580
SRP133303 HDGF 3068 RNAseq 0.4730 0.0019
SRP159526 HDGF 3068 RNAseq 1.0101 0.0000
SRP193095 HDGF 3068 RNAseq 0.5581 0.0001
SRP219564 HDGF 3068 RNAseq 0.6062 0.1231
TCGA HDGF 3068 RNAseq 0.2631 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by HDGF expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of HDGF:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 HDGF 3068 12 0 18
GSE20123 HDGF 3068 12 0 18
GSE43470 HDGF 3068 7 2 34
GSE46452 HDGF 3068 2 1 56
GSE47630 HDGF 3068 14 0 26
GSE54993 HDGF 3068 0 5 65
GSE54994 HDGF 3068 16 0 37
GSE60625 HDGF 3068 0 0 11
GSE74703 HDGF 3068 7 2 27
GSE74704 HDGF 3068 6 0 14
TCGA HDGF 3068 38 2 56

Total number of gains: 114; Total number of losses: 12; Total Number of normals: 362.  

 

Somatic mutations of HDGF:

 

Generating mutation plots.

 

Highly correlated genes for HDGF:

 

Showing top 20/1777 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
HDGFCENPF0.7861712012
HDGFUBE2T0.783265808
HDGFDKC10.774238303
HDGFUBE2C0.76728112011
HDGFMCM40.76661612012
HDGFCKS1B0.76240113013
HDGFCDCA20.759187505
HDGFRTKN0.750491808
HDGFCEP550.75048511011
HDGFMYBL20.75027112011
HDGFBUB10.749231909
HDGFTOP2A0.74725711011
HDGFPBK0.74460210010
HDGFNEK20.74144412011
HDGFCDCA50.74099707
HDGFMTBP0.737131606
HDGFGEN10.73713505
HDGFNUF20.732914807
HDGFDNMT10.73242412012
HDGFTPX20.73077513012

For details and further investigation, click here