| Full name: urocortin | Alias Symbol: UROC|UI | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 7349 | HGNC ID: HGNC:12516 | Ensembl Gene: ENSG00000163794 | OMIM ID: 600945 |
| Drug and gene relationship at DGIdb | |||
Expression of UCN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UCN | 7349 | 206072_at | 0.2042 | 0.4614 | |
| GSE20347 | UCN | 7349 | 206072_at | 0.1780 | 0.1435 | |
| GSE23400 | UCN | 7349 | 206072_at | 0.0592 | 0.0937 | |
| GSE26886 | UCN | 7349 | 206072_at | 0.4635 | 0.0114 | |
| GSE29001 | UCN | 7349 | 206072_at | 0.2523 | 0.0622 | |
| GSE38129 | UCN | 7349 | 206072_at | 0.1934 | 0.0398 | |
| GSE45670 | UCN | 7349 | 206072_at | 0.1063 | 0.4665 | |
| GSE63941 | UCN | 7349 | 206072_at | 0.2573 | 0.4608 | |
| GSE77861 | UCN | 7349 | 206072_at | -0.0033 | 0.9836 | |
| GSE97050 | UCN | 7349 | A_33_P3353030 | 0.0196 | 0.9461 | |
| TCGA | UCN | 7349 | RNAseq | 0.6332 | 0.0582 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UCN expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of UCN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UCN | 7349 | 11 | 2 | 17 | |
| GSE20123 | UCN | 7349 | 11 | 2 | 17 | |
| GSE43470 | UCN | 7349 | 3 | 1 | 39 | |
| GSE46452 | UCN | 7349 | 3 | 4 | 52 | |
| GSE47630 | UCN | 7349 | 8 | 0 | 32 | |
| GSE54993 | UCN | 7349 | 0 | 6 | 64 | |
| GSE54994 | UCN | 7349 | 10 | 0 | 43 | |
| GSE60625 | UCN | 7349 | 0 | 3 | 8 | |
| GSE74703 | UCN | 7349 | 3 | 0 | 33 | |
| GSE74704 | UCN | 7349 | 9 | 1 | 10 | |
| TCGA | UCN | 7349 | 37 | 2 | 57 |
Total number of gains: 95; Total number of losses: 21; Total Number of normals: 372.
Somatic mutations of UCN:
Generating mutation plots.
Highly correlated genes for UCN:
Showing top 20/211 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UCN | CHST3 | 0.834387 | 3 | 0 | 3 |
| UCN | RPTOR | 0.779399 | 3 | 0 | 3 |
| UCN | HCFC1R1 | 0.752323 | 3 | 0 | 3 |
| UCN | BRAT1 | 0.745038 | 3 | 0 | 3 |
| UCN | RNF121 | 0.744338 | 3 | 0 | 3 |
| UCN | PTPN14 | 0.741828 | 3 | 0 | 3 |
| UCN | APLP1 | 0.735728 | 3 | 0 | 3 |
| UCN | VEGFB | 0.731497 | 3 | 0 | 3 |
| UCN | FTO | 0.72989 | 3 | 0 | 3 |
| UCN | RBMS2 | 0.728633 | 3 | 0 | 3 |
| UCN | TBC1D25 | 0.71826 | 3 | 0 | 3 |
| UCN | PIK3CA | 0.710268 | 3 | 0 | 3 |
| UCN | NCAPH2 | 0.709545 | 3 | 0 | 3 |
| UCN | PRKRA | 0.709523 | 3 | 0 | 3 |
| UCN | RILPL1 | 0.701767 | 3 | 0 | 3 |
| UCN | UBIAD1 | 0.695921 | 4 | 0 | 3 |
| UCN | KLF11 | 0.695469 | 3 | 0 | 3 |
| UCN | GHDC | 0.688464 | 3 | 0 | 3 |
| UCN | GRAMD1A | 0.686151 | 3 | 0 | 3 |
| UCN | SPEN | 0.685263 | 4 | 0 | 3 |
For details and further investigation, click here
