| Full name: ring finger protein 121 | Alias Symbol: FLJ11099 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 55298 | HGNC ID: HGNC:21070 | Ensembl Gene: ENSG00000137522 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RNF121:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF121 | 55298 | 219021_at | 0.6857 | 0.0363 | |
| GSE20347 | RNF121 | 55298 | 219021_at | 0.2143 | 0.0104 | |
| GSE23400 | RNF121 | 55298 | 219021_at | 0.1862 | 0.0002 | |
| GSE26886 | RNF121 | 55298 | 219021_at | 0.5886 | 0.1425 | |
| GSE29001 | RNF121 | 55298 | 219021_at | 0.3593 | 0.1280 | |
| GSE38129 | RNF121 | 55298 | 219021_at | 0.1921 | 0.1650 | |
| GSE45670 | RNF121 | 55298 | 219021_at | 0.2708 | 0.1552 | |
| GSE53622 | RNF121 | 55298 | 101327 | -0.6903 | 0.0000 | |
| GSE53624 | RNF121 | 55298 | 101327 | -0.3431 | 0.0003 | |
| GSE63941 | RNF121 | 55298 | 219021_at | -0.0283 | 0.9534 | |
| GSE77861 | RNF121 | 55298 | 219021_at | 0.0782 | 0.6159 | |
| GSE97050 | RNF121 | 55298 | A_23_P75973 | -0.4801 | 0.1616 | |
| SRP007169 | RNF121 | 55298 | RNAseq | 0.4776 | 0.3007 | |
| SRP008496 | RNF121 | 55298 | RNAseq | 0.5874 | 0.0939 | |
| SRP064894 | RNF121 | 55298 | RNAseq | 0.6173 | 0.0032 | |
| SRP133303 | RNF121 | 55298 | RNAseq | 1.3591 | 0.0000 | |
| SRP159526 | RNF121 | 55298 | RNAseq | -0.1297 | 0.5272 | |
| SRP193095 | RNF121 | 55298 | RNAseq | 0.5229 | 0.0090 | |
| SRP219564 | RNF121 | 55298 | RNAseq | 0.9423 | 0.0511 | |
| TCGA | RNF121 | 55298 | RNAseq | 0.1191 | 0.1588 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RNF121 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF121:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF121 | 55298 | 11 | 6 | 13 | |
| GSE20123 | RNF121 | 55298 | 11 | 6 | 13 | |
| GSE43470 | RNF121 | 55298 | 7 | 4 | 32 | |
| GSE46452 | RNF121 | 55298 | 13 | 16 | 30 | |
| GSE47630 | RNF121 | 55298 | 10 | 10 | 20 | |
| GSE54993 | RNF121 | 55298 | 7 | 4 | 59 | |
| GSE54994 | RNF121 | 55298 | 14 | 11 | 28 | |
| GSE60625 | RNF121 | 55298 | 0 | 7 | 4 | |
| GSE74703 | RNF121 | 55298 | 6 | 3 | 27 | |
| GSE74704 | RNF121 | 55298 | 7 | 4 | 9 | |
| TCGA | RNF121 | 55298 | 38 | 19 | 39 |
Total number of gains: 124; Total number of losses: 90; Total Number of normals: 274.
Somatic mutations of RNF121:
Generating mutation plots.
Highly correlated genes for RNF121:
Showing top 20/224 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF121 | ERC1 | 0.773507 | 3 | 0 | 3 |
| RNF121 | NDP | 0.766874 | 3 | 0 | 3 |
| RNF121 | FANCC | 0.762549 | 3 | 0 | 3 |
| RNF121 | KDSR | 0.746513 | 3 | 0 | 3 |
| RNF121 | UCN | 0.744338 | 3 | 0 | 3 |
| RNF121 | PFKM | 0.724788 | 3 | 0 | 3 |
| RNF121 | TRPM7 | 0.723083 | 3 | 0 | 3 |
| RNF121 | EMG1 | 0.717334 | 3 | 0 | 3 |
| RNF121 | BTBD6 | 0.715307 | 3 | 0 | 3 |
| RNF121 | LRRC23 | 0.715208 | 3 | 0 | 3 |
| RNF121 | ARHGEF2 | 0.712782 | 3 | 0 | 3 |
| RNF121 | ZCCHC3 | 0.712638 | 3 | 0 | 3 |
| RNF121 | FAR2 | 0.707721 | 3 | 0 | 3 |
| RNF121 | KCNJ8 | 0.701937 | 3 | 0 | 3 |
| RNF121 | KBTBD6 | 0.700359 | 3 | 0 | 3 |
| RNF121 | CSPP1 | 0.700191 | 3 | 0 | 3 |
| RNF121 | NUP133 | 0.694541 | 3 | 0 | 3 |
| RNF121 | TMEM18 | 0.693982 | 3 | 0 | 3 |
| RNF121 | DCAF17 | 0.693777 | 3 | 0 | 3 |
| RNF121 | HPS3 | 0.691992 | 3 | 0 | 3 |
For details and further investigation, click here
