| Full name: GH3 domain containing | Alias Symbol: LGP1 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 84514 | HGNC ID: HGNC:24438 | Ensembl Gene: ENSG00000167925 | OMIM ID: 608587 |
| Drug and gene relationship at DGIdb | |||
Expression of GHDC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GHDC | 84514 | 227159_at | 0.2332 | 0.5485 | |
| GSE26886 | GHDC | 84514 | 227159_at | 0.4781 | 0.0019 | |
| GSE45670 | GHDC | 84514 | 227159_at | 0.0167 | 0.8890 | |
| GSE53622 | GHDC | 84514 | 25686 | 0.1726 | 0.0232 | |
| GSE53624 | GHDC | 84514 | 25686 | 0.1662 | 0.0088 | |
| GSE63941 | GHDC | 84514 | 227159_at | 0.7954 | 0.1298 | |
| GSE77861 | GHDC | 84514 | 227159_at | -0.0268 | 0.9170 | |
| GSE97050 | GHDC | 84514 | A_23_P207387 | 0.1060 | 0.7069 | |
| SRP007169 | GHDC | 84514 | RNAseq | 0.5912 | 0.2812 | |
| SRP008496 | GHDC | 84514 | RNAseq | 0.5066 | 0.1821 | |
| SRP064894 | GHDC | 84514 | RNAseq | 0.6656 | 0.0118 | |
| SRP133303 | GHDC | 84514 | RNAseq | -0.2665 | 0.2368 | |
| SRP159526 | GHDC | 84514 | RNAseq | 0.0279 | 0.9156 | |
| SRP193095 | GHDC | 84514 | RNAseq | 0.2522 | 0.2803 | |
| SRP219564 | GHDC | 84514 | RNAseq | 0.5564 | 0.1405 | |
| TCGA | GHDC | 84514 | RNAseq | -0.2836 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GHDC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GHDC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GHDC | 84514 | 6 | 2 | 22 | |
| GSE20123 | GHDC | 84514 | 6 | 2 | 22 | |
| GSE43470 | GHDC | 84514 | 1 | 2 | 40 | |
| GSE46452 | GHDC | 84514 | 34 | 0 | 25 | |
| GSE47630 | GHDC | 84514 | 8 | 1 | 31 | |
| GSE54993 | GHDC | 84514 | 3 | 4 | 63 | |
| GSE54994 | GHDC | 84514 | 8 | 5 | 40 | |
| GSE60625 | GHDC | 84514 | 4 | 0 | 7 | |
| GSE74703 | GHDC | 84514 | 1 | 1 | 34 | |
| GSE74704 | GHDC | 84514 | 4 | 1 | 15 | |
| TCGA | GHDC | 84514 | 23 | 6 | 67 |
Total number of gains: 98; Total number of losses: 24; Total Number of normals: 366.
Somatic mutations of GHDC:
Generating mutation plots.
Highly correlated genes for GHDC:
Showing top 20/367 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GHDC | LSM10 | 0.821532 | 3 | 0 | 3 |
| GHDC | GSTO1 | 0.789196 | 3 | 0 | 3 |
| GHDC | CCDC85B | 0.778206 | 3 | 0 | 3 |
| GHDC | PARVB | 0.769109 | 3 | 0 | 3 |
| GHDC | HIP1 | 0.763564 | 4 | 0 | 4 |
| GHDC | TBL1XR1 | 0.762115 | 3 | 0 | 3 |
| GHDC | KCNS3 | 0.760729 | 3 | 0 | 3 |
| GHDC | UNC45A | 0.756339 | 3 | 0 | 3 |
| GHDC | CHD3 | 0.753723 | 3 | 0 | 3 |
| GHDC | FOXJ2 | 0.753107 | 3 | 0 | 3 |
| GHDC | RAB4B | 0.749556 | 3 | 0 | 3 |
| GHDC | SMYD3 | 0.746048 | 3 | 0 | 3 |
| GHDC | CHCHD2 | 0.74511 | 3 | 0 | 3 |
| GHDC | ZNF747 | 0.742216 | 4 | 0 | 4 |
| GHDC | RPS19BP1 | 0.741705 | 3 | 0 | 3 |
| GHDC | TMEM222 | 0.740773 | 3 | 0 | 3 |
| GHDC | SIVA1 | 0.734463 | 3 | 0 | 3 |
| GHDC | C15orf61 | 0.733687 | 3 | 0 | 3 |
| GHDC | PTGES2 | 0.728813 | 3 | 0 | 3 |
| GHDC | CERS2 | 0.727489 | 3 | 0 | 3 |
For details and further investigation, click here
