| Full name: UDP-glucose glycoprotein glucosyltransferase 1 | Alias Symbol: HUGT1 | ||
| Type: protein-coding gene | Cytoband: 2q14.3 | ||
| Entrez ID: 56886 | HGNC ID: HGNC:15663 | Ensembl Gene: ENSG00000136731 | OMIM ID: 605897 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UGGT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UGGT1 | 56886 | 231968_at | 0.6125 | 0.0353 | |
| GSE20347 | UGGT1 | 56886 | 218257_s_at | 0.4656 | 0.0001 | |
| GSE23400 | UGGT1 | 56886 | 218257_s_at | 0.4829 | 0.0000 | |
| GSE26886 | UGGT1 | 56886 | 231968_at | 0.9142 | 0.0007 | |
| GSE29001 | UGGT1 | 56886 | 218257_s_at | 0.6165 | 0.0129 | |
| GSE38129 | UGGT1 | 56886 | 218257_s_at | 0.7085 | 0.0000 | |
| GSE45670 | UGGT1 | 56886 | 231968_at | 0.4744 | 0.0002 | |
| GSE53622 | UGGT1 | 56886 | 13913 | 0.0920 | 0.1033 | |
| GSE53624 | UGGT1 | 56886 | 13913 | 0.3808 | 0.0000 | |
| GSE63941 | UGGT1 | 56886 | 231968_at | -0.6702 | 0.0570 | |
| GSE77861 | UGGT1 | 56886 | 231968_at | 0.4987 | 0.0018 | |
| GSE97050 | UGGT1 | 56886 | A_33_P3366246 | 0.4197 | 0.2247 | |
| SRP007169 | UGGT1 | 56886 | RNAseq | 1.4021 | 0.0002 | |
| SRP008496 | UGGT1 | 56886 | RNAseq | 1.4405 | 0.0000 | |
| SRP064894 | UGGT1 | 56886 | RNAseq | 0.6456 | 0.0000 | |
| SRP133303 | UGGT1 | 56886 | RNAseq | 0.7515 | 0.0000 | |
| SRP159526 | UGGT1 | 56886 | RNAseq | 0.7335 | 0.0017 | |
| SRP193095 | UGGT1 | 56886 | RNAseq | 0.3267 | 0.0014 | |
| SRP219564 | UGGT1 | 56886 | RNAseq | 0.4599 | 0.0871 | |
| TCGA | UGGT1 | 56886 | RNAseq | 0.0023 | 0.9579 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by UGGT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UGGT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UGGT1 | 56886 | 6 | 3 | 21 | |
| GSE20123 | UGGT1 | 56886 | 6 | 3 | 21 | |
| GSE43470 | UGGT1 | 56886 | 2 | 1 | 40 | |
| GSE46452 | UGGT1 | 56886 | 1 | 3 | 55 | |
| GSE47630 | UGGT1 | 56886 | 6 | 0 | 34 | |
| GSE54993 | UGGT1 | 56886 | 0 | 6 | 64 | |
| GSE54994 | UGGT1 | 56886 | 11 | 0 | 42 | |
| GSE60625 | UGGT1 | 56886 | 0 | 3 | 8 | |
| GSE74703 | UGGT1 | 56886 | 2 | 1 | 33 | |
| GSE74704 | UGGT1 | 56886 | 3 | 1 | 16 | |
| TCGA | UGGT1 | 56886 | 22 | 8 | 66 |
Total number of gains: 59; Total number of losses: 29; Total Number of normals: 400.
Somatic mutations of UGGT1:
Generating mutation plots.
Highly correlated genes for UGGT1:
Showing top 20/967 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UGGT1 | DNAJC10 | 0.737933 | 9 | 0 | 9 |
| UGGT1 | NIFK | 0.737511 | 4 | 0 | 4 |
| UGGT1 | GORAB | 0.735362 | 5 | 0 | 5 |
| UGGT1 | REL | 0.734853 | 3 | 0 | 3 |
| UGGT1 | TENM2 | 0.729261 | 3 | 0 | 3 |
| UGGT1 | ABCC10 | 0.717541 | 3 | 0 | 3 |
| UGGT1 | PHLDB2 | 0.707874 | 3 | 0 | 3 |
| UGGT1 | TRIM59 | 0.70607 | 3 | 0 | 3 |
| UGGT1 | BUB1 | 0.704322 | 7 | 0 | 6 |
| UGGT1 | XPR1 | 0.701208 | 5 | 0 | 5 |
| UGGT1 | ZNF623 | 0.699085 | 4 | 0 | 4 |
| UGGT1 | TNFAIP8L1 | 0.697031 | 4 | 0 | 4 |
| UGGT1 | FMNL2 | 0.693302 | 5 | 0 | 5 |
| UGGT1 | TANGO2 | 0.692696 | 5 | 0 | 5 |
| UGGT1 | SLFN5 | 0.687774 | 3 | 0 | 3 |
| UGGT1 | ACLY | 0.685138 | 7 | 0 | 7 |
| UGGT1 | AHCTF1 | 0.681895 | 8 | 0 | 7 |
| UGGT1 | FEZ2 | 0.677823 | 3 | 0 | 3 |
| UGGT1 | SPP1 | 0.67642 | 9 | 0 | 8 |
| UGGT1 | HPS3 | 0.673797 | 4 | 0 | 3 |
For details and further investigation, click here
