| Full name: UDP glucuronosyltransferase family 2 member A3 | Alias Symbol: FLJ21934 | ||
| Type: protein-coding gene | Cytoband: 4q13.2 | ||
| Entrez ID: 79799 | HGNC ID: HGNC:28528 | Ensembl Gene: ENSG00000135220 | OMIM ID: 616382 |
| Drug and gene relationship at DGIdb | |||
Expression of UGT2A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UGT2A3 | 79799 | 219948_x_at | -0.0325 | 0.8979 | |
| GSE20347 | UGT2A3 | 79799 | 219948_x_at | -0.0351 | 0.3433 | |
| GSE23400 | UGT2A3 | 79799 | 219948_x_at | -0.0193 | 0.1896 | |
| GSE26886 | UGT2A3 | 79799 | 219948_x_at | -0.0870 | 0.3239 | |
| GSE29001 | UGT2A3 | 79799 | 219948_x_at | -0.0044 | 0.9795 | |
| GSE38129 | UGT2A3 | 79799 | 219948_x_at | -0.0500 | 0.2111 | |
| GSE45670 | UGT2A3 | 79799 | 219948_x_at | -0.0224 | 0.7859 | |
| GSE53622 | UGT2A3 | 79799 | 18511 | -0.2126 | 0.1130 | |
| GSE53624 | UGT2A3 | 79799 | 18511 | -0.2383 | 0.0942 | |
| GSE63941 | UGT2A3 | 79799 | 219948_x_at | -0.0540 | 0.6532 | |
| GSE77861 | UGT2A3 | 79799 | 219948_x_at | -0.0423 | 0.5253 | |
| TCGA | UGT2A3 | 79799 | RNAseq | -3.4838 | 0.0095 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UGT2A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UGT2A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UGT2A3 | 79799 | 0 | 11 | 19 | |
| GSE20123 | UGT2A3 | 79799 | 0 | 12 | 18 | |
| GSE43470 | UGT2A3 | 79799 | 0 | 13 | 30 | |
| GSE46452 | UGT2A3 | 79799 | 2 | 35 | 22 | |
| GSE47630 | UGT2A3 | 79799 | 1 | 18 | 21 | |
| GSE54993 | UGT2A3 | 79799 | 7 | 0 | 63 | |
| GSE54994 | UGT2A3 | 79799 | 1 | 9 | 43 | |
| GSE60625 | UGT2A3 | 79799 | 0 | 0 | 11 | |
| GSE74703 | UGT2A3 | 79799 | 0 | 11 | 25 | |
| GSE74704 | UGT2A3 | 79799 | 0 | 8 | 12 | |
| TCGA | UGT2A3 | 79799 | 18 | 26 | 52 |
Total number of gains: 29; Total number of losses: 143; Total Number of normals: 316.
Somatic mutations of UGT2A3:
Generating mutation plots.
Highly correlated genes for UGT2A3:
Showing top 20/112 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UGT2A3 | TAAR2 | 0.717455 | 3 | 0 | 3 |
| UGT2A3 | LMAN1L | 0.71012 | 3 | 0 | 3 |
| UGT2A3 | NPY5R | 0.695074 | 3 | 0 | 3 |
| UGT2A3 | DNAI1 | 0.680019 | 3 | 0 | 3 |
| UGT2A3 | MATN1 | 0.679411 | 3 | 0 | 3 |
| UGT2A3 | NCAN | 0.676841 | 4 | 0 | 4 |
| UGT2A3 | GNRHR | 0.674065 | 3 | 0 | 3 |
| UGT2A3 | GABRA5 | 0.670621 | 4 | 0 | 4 |
| UGT2A3 | ARPP21 | 0.666762 | 3 | 0 | 3 |
| UGT2A3 | MSH4 | 0.660177 | 3 | 0 | 3 |
| UGT2A3 | GUCY2F | 0.659663 | 3 | 0 | 3 |
| UGT2A3 | CCDC33 | 0.656252 | 4 | 0 | 4 |
| UGT2A3 | TAS2R16 | 0.651454 | 3 | 0 | 3 |
| UGT2A3 | KSR1 | 0.651004 | 3 | 0 | 3 |
| UGT2A3 | PIWIL2 | 0.641598 | 3 | 0 | 3 |
| UGT2A3 | IFNA16 | 0.641315 | 5 | 0 | 5 |
| UGT2A3 | NR6A1 | 0.641268 | 4 | 0 | 4 |
| UGT2A3 | SIRT3 | 0.641212 | 3 | 0 | 3 |
| UGT2A3 | FGF5 | 0.639696 | 4 | 0 | 4 |
| UGT2A3 | ATP6V1G2 | 0.639221 | 3 | 0 | 3 |
For details and further investigation, click here
