| Full name: spermatogenesis associated 5 like 1 | Alias Symbol: MGC5347|FLJ12286 | ||
| Type: protein-coding gene | Cytoband: 15q21.1 | ||
| Entrez ID: 79029 | HGNC ID: HGNC:28762 | Ensembl Gene: ENSG00000171763 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SPATA5L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPATA5L1 | 79029 | 222163_s_at | -0.2852 | 0.6692 | |
| GSE20347 | SPATA5L1 | 79029 | 222163_s_at | -0.6681 | 0.0007 | |
| GSE23400 | SPATA5L1 | 79029 | 222163_s_at | -0.7261 | 0.0000 | |
| GSE26886 | SPATA5L1 | 79029 | 222163_s_at | -0.9075 | 0.0008 | |
| GSE29001 | SPATA5L1 | 79029 | 222163_s_at | -0.9221 | 0.0322 | |
| GSE38129 | SPATA5L1 | 79029 | 222163_s_at | -0.3294 | 0.0975 | |
| GSE45670 | SPATA5L1 | 79029 | 222163_s_at | -0.4151 | 0.0453 | |
| GSE53622 | SPATA5L1 | 79029 | 26946 | -0.5952 | 0.0000 | |
| GSE53624 | SPATA5L1 | 79029 | 26946 | -0.8218 | 0.0000 | |
| GSE63941 | SPATA5L1 | 79029 | 222163_s_at | 0.1712 | 0.6384 | |
| GSE77861 | SPATA5L1 | 79029 | 222163_s_at | -1.0758 | 0.0276 | |
| GSE97050 | SPATA5L1 | 79029 | A_23_P37424 | -0.0243 | 0.9480 | |
| SRP007169 | SPATA5L1 | 79029 | RNAseq | -1.7601 | 0.0001 | |
| SRP064894 | SPATA5L1 | 79029 | RNAseq | -1.1441 | 0.0000 | |
| SRP133303 | SPATA5L1 | 79029 | RNAseq | -0.6209 | 0.0030 | |
| SRP159526 | SPATA5L1 | 79029 | RNAseq | -1.1413 | 0.0007 | |
| SRP193095 | SPATA5L1 | 79029 | RNAseq | -1.1013 | 0.0000 | |
| SRP219564 | SPATA5L1 | 79029 | RNAseq | -1.4935 | 0.0001 | |
| TCGA | SPATA5L1 | 79029 | RNAseq | 0.2174 | 0.0021 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by SPATA5L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPATA5L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPATA5L1 | 79029 | 4 | 5 | 21 | |
| GSE20123 | SPATA5L1 | 79029 | 4 | 5 | 21 | |
| GSE43470 | SPATA5L1 | 79029 | 4 | 4 | 35 | |
| GSE46452 | SPATA5L1 | 79029 | 3 | 7 | 49 | |
| GSE47630 | SPATA5L1 | 79029 | 8 | 10 | 22 | |
| GSE54993 | SPATA5L1 | 79029 | 4 | 5 | 61 | |
| GSE54994 | SPATA5L1 | 79029 | 5 | 7 | 41 | |
| GSE60625 | SPATA5L1 | 79029 | 4 | 0 | 7 | |
| GSE74703 | SPATA5L1 | 79029 | 4 | 3 | 29 | |
| GSE74704 | SPATA5L1 | 79029 | 2 | 3 | 15 | |
| TCGA | SPATA5L1 | 79029 | 11 | 16 | 69 |
Total number of gains: 53; Total number of losses: 65; Total Number of normals: 370.
Somatic mutations of SPATA5L1:
Generating mutation plots.
Highly correlated genes for SPATA5L1:
Showing top 20/1509 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPATA5L1 | UNC5CL | 0.776215 | 3 | 0 | 3 |
| SPATA5L1 | EXOC4 | 0.756653 | 3 | 0 | 3 |
| SPATA5L1 | TLE4 | 0.750002 | 3 | 0 | 3 |
| SPATA5L1 | ANKHD1 | 0.74643 | 3 | 0 | 3 |
| SPATA5L1 | ULK3 | 0.739787 | 7 | 0 | 7 |
| SPATA5L1 | HDHD2 | 0.739016 | 4 | 0 | 4 |
| SPATA5L1 | C18orf25 | 0.734451 | 11 | 0 | 11 |
| SPATA5L1 | GABPA | 0.734392 | 3 | 0 | 3 |
| SPATA5L1 | C15orf62 | 0.733375 | 7 | 0 | 7 |
| SPATA5L1 | DDI2 | 0.731526 | 3 | 0 | 3 |
| SPATA5L1 | PPP1R8 | 0.730775 | 3 | 0 | 3 |
| SPATA5L1 | NUAK2 | 0.728989 | 3 | 0 | 3 |
| SPATA5L1 | COMTD1 | 0.720595 | 5 | 0 | 5 |
| SPATA5L1 | MFN1 | 0.715407 | 3 | 0 | 3 |
| SPATA5L1 | CHP1 | 0.715095 | 11 | 0 | 10 |
| SPATA5L1 | TMEM120A | 0.713397 | 6 | 0 | 6 |
| SPATA5L1 | ARHGAP27 | 0.710841 | 7 | 0 | 7 |
| SPATA5L1 | MAGI3 | 0.710042 | 6 | 0 | 6 |
| SPATA5L1 | C12orf29 | 0.708212 | 11 | 0 | 11 |
| SPATA5L1 | TSPAN6 | 0.706492 | 11 | 0 | 11 |
For details and further investigation, click here
