| Full name: RAS like estrogen regulated growth inhibitor | Alias Symbol: MGC15754 | ||
| Type: protein-coding gene | Cytoband: 12p12.3 | ||
| Entrez ID: 85004 | HGNC ID: HGNC:15980 | Ensembl Gene: ENSG00000134533 | OMIM ID: 612664 |
| Drug and gene relationship at DGIdb | |||
Expression of RERG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RERG | 85004 | 227758_at | -0.7084 | 0.4851 | |
| GSE26886 | RERG | 85004 | 227758_at | 0.6413 | 0.2513 | |
| GSE45670 | RERG | 85004 | 227758_at | -2.2197 | 0.0000 | |
| GSE53622 | RERG | 85004 | 77926 | -1.4330 | 0.0000 | |
| GSE53624 | RERG | 85004 | 77926 | -1.5576 | 0.0000 | |
| GSE63941 | RERG | 85004 | 227758_at | -1.2464 | 0.2890 | |
| GSE77861 | RERG | 85004 | 227758_at | -0.0024 | 0.9915 | |
| GSE97050 | RERG | 85004 | A_24_P321525 | -0.4758 | 0.2616 | |
| SRP064894 | RERG | 85004 | RNAseq | -0.8398 | 0.0367 | |
| SRP133303 | RERG | 85004 | RNAseq | -1.5526 | 0.0000 | |
| SRP159526 | RERG | 85004 | RNAseq | -0.7074 | 0.0145 | |
| SRP193095 | RERG | 85004 | RNAseq | 0.1913 | 0.5142 | |
| SRP219564 | RERG | 85004 | RNAseq | -0.2323 | 0.7397 | |
| TCGA | RERG | 85004 | RNAseq | -0.4375 | 0.0257 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by RERG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RERG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RERG | 85004 | 6 | 2 | 22 | |
| GSE20123 | RERG | 85004 | 6 | 2 | 22 | |
| GSE43470 | RERG | 85004 | 9 | 4 | 30 | |
| GSE46452 | RERG | 85004 | 10 | 1 | 48 | |
| GSE47630 | RERG | 85004 | 14 | 1 | 25 | |
| GSE54993 | RERG | 85004 | 1 | 9 | 60 | |
| GSE54994 | RERG | 85004 | 10 | 2 | 41 | |
| GSE60625 | RERG | 85004 | 0 | 1 | 10 | |
| GSE74703 | RERG | 85004 | 9 | 3 | 24 | |
| GSE74704 | RERG | 85004 | 4 | 1 | 15 | |
| TCGA | RERG | 85004 | 42 | 4 | 50 |
Total number of gains: 111; Total number of losses: 30; Total Number of normals: 347.
Somatic mutations of RERG:
Generating mutation plots.
Highly correlated genes for RERG:
Showing top 20/920 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RERG | TCF21 | 0.794391 | 5 | 0 | 5 |
| RERG | NR2F1 | 0.777857 | 3 | 0 | 3 |
| RERG | MFAP4 | 0.767242 | 5 | 0 | 5 |
| RERG | FIBIN | 0.765155 | 3 | 0 | 3 |
| RERG | NPY1R | 0.761933 | 4 | 0 | 4 |
| RERG | OGN | 0.760765 | 5 | 0 | 5 |
| RERG | ASPA | 0.754945 | 5 | 0 | 5 |
| RERG | CLEC3B | 0.751738 | 3 | 0 | 3 |
| RERG | PEG3 | 0.7505 | 3 | 0 | 3 |
| RERG | RECK | 0.750435 | 4 | 0 | 4 |
| RERG | RGN | 0.749268 | 5 | 0 | 5 |
| RERG | ITGA8 | 0.746705 | 5 | 0 | 5 |
| RERG | ACP6 | 0.746693 | 3 | 0 | 3 |
| RERG | CADM3 | 0.745138 | 3 | 0 | 3 |
| RERG | AOC3 | 0.74113 | 5 | 0 | 5 |
| RERG | THYN1 | 0.741104 | 4 | 0 | 4 |
| RERG | USP9X | 0.739822 | 4 | 0 | 4 |
| RERG | CBX7 | 0.735692 | 5 | 0 | 5 |
| RERG | CASQ2 | 0.73474 | 5 | 0 | 5 |
| RERG | RNF125 | 0.733171 | 5 | 0 | 5 |
For details and further investigation, click here
