| Full name: solute carrier family 18 member A2 | Alias Symbol: SVMT|SVAT | ||
| Type: protein-coding gene | Cytoband: 10q25.3 | ||
| Entrez ID: 6571 | HGNC ID: HGNC:10935 | Ensembl Gene: ENSG00000165646 | OMIM ID: 193001 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC18A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC18A2 | 6571 | 205857_at | -0.8177 | 0.2148 | |
| GSE20347 | SLC18A2 | 6571 | 205857_at | -0.3899 | 0.0001 | |
| GSE23400 | SLC18A2 | 6571 | 205857_at | -0.1670 | 0.0002 | |
| GSE26886 | SLC18A2 | 6571 | 205857_at | -0.4614 | 0.0355 | |
| GSE29001 | SLC18A2 | 6571 | 205857_at | -0.4738 | 0.0044 | |
| GSE38129 | SLC18A2 | 6571 | 205857_at | -0.4488 | 0.0001 | |
| GSE45670 | SLC18A2 | 6571 | 205857_at | -0.8102 | 0.0114 | |
| GSE53622 | SLC18A2 | 6571 | 65134 | -1.2945 | 0.0000 | |
| GSE53624 | SLC18A2 | 6571 | 65134 | -1.2536 | 0.0000 | |
| GSE63941 | SLC18A2 | 6571 | 205857_at | 0.8427 | 0.2800 | |
| GSE77861 | SLC18A2 | 6571 | 1553328_a_at | -0.0412 | 0.6992 | |
| GSE97050 | SLC18A2 | 6571 | A_23_P52499 | -0.0034 | 0.9907 | |
| SRP064894 | SLC18A2 | 6571 | RNAseq | -0.6874 | 0.0673 | |
| SRP133303 | SLC18A2 | 6571 | RNAseq | -1.4460 | 0.0000 | |
| SRP159526 | SLC18A2 | 6571 | RNAseq | -0.4364 | 0.3356 | |
| SRP193095 | SLC18A2 | 6571 | RNAseq | -0.7444 | 0.0041 | |
| SRP219564 | SLC18A2 | 6571 | RNAseq | -0.1331 | 0.7846 | |
| TCGA | SLC18A2 | 6571 | RNAseq | -1.9228 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SLC18A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC18A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC18A2 | 6571 | 1 | 7 | 22 | |
| GSE20123 | SLC18A2 | 6571 | 1 | 7 | 22 | |
| GSE43470 | SLC18A2 | 6571 | 0 | 9 | 34 | |
| GSE46452 | SLC18A2 | 6571 | 0 | 11 | 48 | |
| GSE47630 | SLC18A2 | 6571 | 2 | 14 | 24 | |
| GSE54993 | SLC18A2 | 6571 | 8 | 0 | 62 | |
| GSE54994 | SLC18A2 | 6571 | 1 | 9 | 43 | |
| GSE60625 | SLC18A2 | 6571 | 0 | 0 | 11 | |
| GSE74703 | SLC18A2 | 6571 | 0 | 6 | 30 | |
| GSE74704 | SLC18A2 | 6571 | 1 | 3 | 16 | |
| TCGA | SLC18A2 | 6571 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 94; Total Number of normals: 376.
Somatic mutations of SLC18A2:
Generating mutation plots.
Highly correlated genes for SLC18A2:
Showing top 20/790 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC18A2 | CHMP5 | 0.753992 | 3 | 0 | 3 |
| SLC18A2 | TMED4 | 0.7305 | 3 | 0 | 3 |
| SLC18A2 | COX15 | 0.727523 | 3 | 0 | 3 |
| SLC18A2 | CPA3 | 0.725012 | 10 | 0 | 9 |
| SLC18A2 | NR2F1 | 0.713414 | 3 | 0 | 3 |
| SLC18A2 | USP19 | 0.692962 | 3 | 0 | 3 |
| SLC18A2 | CLEC3B | 0.692613 | 3 | 0 | 3 |
| SLC18A2 | CPVL | 0.691717 | 5 | 0 | 4 |
| SLC18A2 | ARHGAP20 | 0.690299 | 3 | 0 | 3 |
| SLC18A2 | PLK3 | 0.68393 | 3 | 0 | 3 |
| SLC18A2 | ARHGAP15 | 0.683902 | 3 | 0 | 3 |
| SLC18A2 | RECQL5 | 0.680395 | 4 | 0 | 4 |
| SLC18A2 | FBXO8 | 0.67561 | 5 | 0 | 5 |
| SLC18A2 | CYP4V2 | 0.675365 | 3 | 0 | 3 |
| SLC18A2 | CCL23 | 0.674734 | 3 | 0 | 3 |
| SLC18A2 | GIMAP1 | 0.673025 | 5 | 0 | 4 |
| SLC18A2 | PLCXD3 | 0.671764 | 5 | 0 | 5 |
| SLC18A2 | SAMD3 | 0.670187 | 3 | 0 | 3 |
| SLC18A2 | TPSB2 | 0.668238 | 8 | 0 | 6 |
| SLC18A2 | PXK | 0.667687 | 6 | 0 | 5 |
For details and further investigation, click here
