| Full name: ubiquitin specific peptidase like 1 | Alias Symbol: bA121O19.1|D13S106E | ||
| Type: protein-coding gene | Cytoband: 13q12.3 | ||
| Entrez ID: 10208 | HGNC ID: HGNC:20294 | Ensembl Gene: ENSG00000132952 | OMIM ID: 617470 |
| Drug and gene relationship at DGIdb | |||
Expression of USPL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USPL1 | 10208 | 204190_at | -0.2275 | 0.6935 | |
| GSE20347 | USPL1 | 10208 | 204190_at | 0.0695 | 0.6425 | |
| GSE23400 | USPL1 | 10208 | 204190_at | 0.1077 | 0.0612 | |
| GSE26886 | USPL1 | 10208 | 204190_at | 0.9249 | 0.0198 | |
| GSE29001 | USPL1 | 10208 | 204190_at | 0.0787 | 0.8509 | |
| GSE38129 | USPL1 | 10208 | 204190_at | -0.0030 | 0.9846 | |
| GSE45670 | USPL1 | 10208 | 204190_at | -0.1374 | 0.5468 | |
| GSE53622 | USPL1 | 10208 | 55676 | 0.3405 | 0.0002 | |
| GSE53624 | USPL1 | 10208 | 55676 | 0.2064 | 0.0133 | |
| GSE63941 | USPL1 | 10208 | 204190_at | 0.1623 | 0.7054 | |
| GSE77861 | USPL1 | 10208 | 204190_at | 0.1597 | 0.5995 | |
| GSE97050 | USPL1 | 10208 | A_23_P128641 | 0.2238 | 0.3531 | |
| SRP007169 | USPL1 | 10208 | RNAseq | 0.5785 | 0.1527 | |
| SRP008496 | USPL1 | 10208 | RNAseq | 0.7225 | 0.0132 | |
| SRP064894 | USPL1 | 10208 | RNAseq | 0.3176 | 0.0673 | |
| SRP133303 | USPL1 | 10208 | RNAseq | 0.0652 | 0.6995 | |
| SRP159526 | USPL1 | 10208 | RNAseq | -0.2207 | 0.3658 | |
| SRP193095 | USPL1 | 10208 | RNAseq | -0.1341 | 0.1864 | |
| SRP219564 | USPL1 | 10208 | RNAseq | -0.1874 | 0.5919 | |
| TCGA | USPL1 | 10208 | RNAseq | -0.1495 | 0.0088 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by USPL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USPL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USPL1 | 10208 | 1 | 13 | 16 | |
| GSE20123 | USPL1 | 10208 | 1 | 12 | 17 | |
| GSE43470 | USPL1 | 10208 | 2 | 12 | 29 | |
| GSE46452 | USPL1 | 10208 | 0 | 33 | 26 | |
| GSE47630 | USPL1 | 10208 | 2 | 27 | 11 | |
| GSE54993 | USPL1 | 10208 | 12 | 2 | 56 | |
| GSE54994 | USPL1 | 10208 | 2 | 15 | 36 | |
| GSE60625 | USPL1 | 10208 | 0 | 3 | 8 | |
| GSE74703 | USPL1 | 10208 | 2 | 9 | 25 | |
| GSE74704 | USPL1 | 10208 | 0 | 10 | 10 | |
| TCGA | USPL1 | 10208 | 8 | 37 | 51 |
Total number of gains: 30; Total number of losses: 173; Total Number of normals: 285.
Somatic mutations of USPL1:
Generating mutation plots.
Highly correlated genes for USPL1:
Showing top 20/477 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USPL1 | SAT2 | 0.805885 | 3 | 0 | 3 |
| USPL1 | ZCCHC7 | 0.780483 | 3 | 0 | 3 |
| USPL1 | ZNF836 | 0.775024 | 3 | 0 | 3 |
| USPL1 | SCAMP1-AS1 | 0.748519 | 3 | 0 | 3 |
| USPL1 | CPLX1 | 0.740588 | 3 | 0 | 3 |
| USPL1 | CWF19L2 | 0.739643 | 4 | 0 | 4 |
| USPL1 | PRKCA | 0.730094 | 3 | 0 | 3 |
| USPL1 | BVES | 0.725683 | 3 | 0 | 3 |
| USPL1 | C1GALT1C1 | 0.721714 | 3 | 0 | 3 |
| USPL1 | ACP6 | 0.715198 | 3 | 0 | 3 |
| USPL1 | LPGAT1 | 0.71073 | 3 | 0 | 3 |
| USPL1 | PTGES3 | 0.709049 | 3 | 0 | 3 |
| USPL1 | NAP1L1 | 0.702553 | 5 | 0 | 4 |
| USPL1 | METAP2 | 0.701781 | 3 | 0 | 3 |
| USPL1 | COG3 | 0.695128 | 3 | 0 | 3 |
| USPL1 | GNG11 | 0.691048 | 3 | 0 | 3 |
| USPL1 | RNF139 | 0.690635 | 3 | 0 | 3 |
| USPL1 | PSMC3 | 0.686039 | 3 | 0 | 3 |
| USPL1 | N4BP2L1 | 0.682623 | 4 | 0 | 3 |
| USPL1 | MTOR | 0.682121 | 3 | 0 | 3 |
For details and further investigation, click here
