PSMD11

 

Full name: proteasome 26S subunit, non-ATPase 11 Alias Symbol: S9|p44.5|MGC3844|Rpn6
Type: protein-coding gene Cytoband: 17q11.2
Entrez ID: 5717 HGNC ID: HGNC:9556 Ensembl Gene: ENSG00000108671 OMIM ID: 604449
Drug and gene relationship at DGIdb

 

Expression of PSMD11:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PSMD11 5717 208777_s_at 0.5714 0.1282
GSE20347 PSMD11 5717 208777_s_at 0.8794 0.0015
GSE23400 PSMD11 5717 208777_s_at 0.7011 0.0000
GSE26886 PSMD11 5717 208777_s_at -0.2650 0.2693
GSE29001 PSMD11 5717 208777_s_at 0.4420 0.1854
GSE38129 PSMD11 5717 208777_s_at 1.0739 0.0000
GSE45670 PSMD11 5717 208777_s_at 0.4351 0.0404
GSE53622 PSMD11 5717 94980 0.5900 0.0000
GSE53624 PSMD11 5717 94980 0.5015 0.0000
GSE63941 PSMD11 5717 208777_s_at 1.4441 0.0006
GSE77861 PSMD11 5717 208777_s_at 0.9883 0.0008
GSE97050 PSMD11 5717 A_23_P207600 0.4958 0.1557
SRP007169 PSMD11 5717 RNAseq 0.5553 0.0452
SRP008496 PSMD11 5717 RNAseq 0.2555 0.2780
SRP064894 PSMD11 5717 RNAseq 0.4591 0.0094
SRP133303 PSMD11 5717 RNAseq 0.6232 0.0001
SRP159526 PSMD11 5717 RNAseq 0.7981 0.0000
SRP193095 PSMD11 5717 RNAseq 0.5396 0.0001
SRP219564 PSMD11 5717 RNAseq 0.4980 0.1891
TCGA PSMD11 5717 RNAseq 0.3044 0.0000

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by PSMD11 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PSMD11:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PSMD11 5717 9 2 19
GSE20123 PSMD11 5717 9 2 19
GSE43470 PSMD11 5717 1 1 41
GSE46452 PSMD11 5717 33 1 25
GSE47630 PSMD11 5717 7 1 32
GSE54993 PSMD11 5717 3 3 64
GSE54994 PSMD11 5717 7 6 40
GSE60625 PSMD11 5717 4 0 7
GSE74703 PSMD11 5717 1 1 34
GSE74704 PSMD11 5717 6 2 12
TCGA PSMD11 5717 19 9 68

Total number of gains: 99; Total number of losses: 28; Total Number of normals: 361.  

 

Somatic mutations of PSMD11:

 

Generating mutation plots.

 

Highly correlated genes for PSMD11:

 

Showing top 20/1089 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PSMD11PSMD30.7476781009
PSMD11TUBG10.731645909
PSMD11HAS30.730616505
PSMD11COTL10.722544303
PSMD11IMP40.72204210010
PSMD11CCT70.72197510010
PSMD11RUVBL10.72194211011
PSMD11PSMD20.7214441009
PSMD11DDX39A0.71504610010
PSMD11HNRNPC0.714828808
PSMD11EFTUD20.714298606
PSMD11SNRPG0.708646808
PSMD11ACLY0.708457808
PSMD11PSMD120.70198211010
PSMD11UTP60.70190611010
PSMD11TTYH30.701859404
PSMD11NMT10.70148210010
PSMD11AATF0.6991911010
PSMD11NOL110.698191009
PSMD11FEN10.697957707

For details and further investigation, click here