| Full name: vanin 2 | Alias Symbol: FOAP-4|GPI-80 | ||
| Type: protein-coding gene | Cytoband: 6q23.2 | ||
| Entrez ID: 8875 | HGNC ID: HGNC:12706 | Ensembl Gene: ENSG00000112303 | OMIM ID: 603571 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of VNN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VNN2 | 8875 | 205922_at | 0.8265 | 0.3958 | |
| GSE20347 | VNN2 | 8875 | 205922_at | 0.1932 | 0.1301 | |
| GSE23400 | VNN2 | 8875 | 205922_at | -0.0310 | 0.5570 | |
| GSE26886 | VNN2 | 8875 | 205922_at | 0.0488 | 0.8235 | |
| GSE29001 | VNN2 | 8875 | 205922_at | 0.1170 | 0.7151 | |
| GSE38129 | VNN2 | 8875 | 205922_at | 0.0074 | 0.9693 | |
| GSE45670 | VNN2 | 8875 | 205922_at | 0.5610 | 0.2262 | |
| GSE53622 | VNN2 | 8875 | 20504 | 0.0558 | 0.6723 | |
| GSE53624 | VNN2 | 8875 | 20504 | -0.1278 | 0.2451 | |
| GSE63941 | VNN2 | 8875 | 205922_at | 0.2858 | 0.8168 | |
| GSE77861 | VNN2 | 8875 | 205922_at | -0.0624 | 0.6082 | |
| GSE97050 | VNN2 | 8875 | A_23_P122724 | 0.0815 | 0.9010 | |
| SRP064894 | VNN2 | 8875 | RNAseq | 0.5145 | 0.2094 | |
| SRP133303 | VNN2 | 8875 | RNAseq | 1.4452 | 0.0044 | |
| SRP159526 | VNN2 | 8875 | RNAseq | 0.2776 | 0.7953 | |
| SRP193095 | VNN2 | 8875 | RNAseq | 1.1739 | 0.0052 | |
| TCGA | VNN2 | 8875 | RNAseq | -0.3671 | 0.3423 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by VNN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VNN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VNN2 | 8875 | 3 | 4 | 23 | |
| GSE20123 | VNN2 | 8875 | 3 | 3 | 24 | |
| GSE43470 | VNN2 | 8875 | 5 | 0 | 38 | |
| GSE46452 | VNN2 | 8875 | 2 | 11 | 46 | |
| GSE47630 | VNN2 | 8875 | 9 | 4 | 27 | |
| GSE54993 | VNN2 | 8875 | 3 | 2 | 65 | |
| GSE54994 | VNN2 | 8875 | 9 | 7 | 37 | |
| GSE60625 | VNN2 | 8875 | 0 | 1 | 10 | |
| GSE74703 | VNN2 | 8875 | 4 | 0 | 32 | |
| GSE74704 | VNN2 | 8875 | 1 | 1 | 18 | |
| TCGA | VNN2 | 8875 | 11 | 18 | 67 |
Total number of gains: 50; Total number of losses: 51; Total Number of normals: 387.
Somatic mutations of VNN2:
Generating mutation plots.
Highly correlated genes for VNN2:
Showing top 20/200 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VNN2 | RNF183 | 0.745473 | 3 | 0 | 3 |
| VNN2 | MBTPS1 | 0.728393 | 3 | 0 | 3 |
| VNN2 | C8orf44 | 0.717952 | 3 | 0 | 3 |
| VNN2 | CD83 | 0.708557 | 3 | 0 | 3 |
| VNN2 | SNAI3 | 0.705476 | 3 | 0 | 3 |
| VNN2 | BCAS4 | 0.704451 | 4 | 0 | 3 |
| VNN2 | KIF3C | 0.699875 | 4 | 0 | 3 |
| VNN2 | IL13RA2 | 0.687948 | 3 | 0 | 3 |
| VNN2 | DACT2 | 0.687889 | 3 | 0 | 3 |
| VNN2 | CTSH | 0.67641 | 4 | 0 | 3 |
| VNN2 | POPDC2 | 0.667417 | 3 | 0 | 3 |
| VNN2 | MFN2 | 0.658023 | 3 | 0 | 3 |
| VNN2 | PROK2 | 0.656829 | 6 | 0 | 5 |
| VNN2 | NOTCH4 | 0.655824 | 3 | 0 | 3 |
| VNN2 | TGFB2 | 0.651253 | 4 | 0 | 4 |
| VNN2 | SH3KBP1 | 0.649415 | 4 | 0 | 3 |
| VNN2 | KRT81 | 0.647073 | 4 | 0 | 3 |
| VNN2 | ZNF771 | 0.645393 | 4 | 0 | 3 |
| VNN2 | C16orf54 | 0.642125 | 7 | 0 | 5 |
| VNN2 | SLC6A6 | 0.637169 | 5 | 0 | 3 |
For details and further investigation, click here
