| Full name: dishevelled binding antagonist of beta catenin 2 | Alias Symbol: bA503C24.7|DAPPER2 | ||
| Type: protein-coding gene | Cytoband: 6q27 | ||
| Entrez ID: 168002 | HGNC ID: HGNC:21231 | Ensembl Gene: ENSG00000164488 | OMIM ID: 608966 |
| Drug and gene relationship at DGIdb | |||
Expression of DACT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DACT2 | 168002 | 1569648_at | 0.0995 | 0.9145 | |
| GSE26886 | DACT2 | 168002 | 1569648_at | 0.3685 | 0.0261 | |
| GSE45670 | DACT2 | 168002 | 1569648_at | 0.0904 | 0.5896 | |
| GSE53622 | DACT2 | 168002 | 38499 | 0.2295 | 0.4620 | |
| GSE53624 | DACT2 | 168002 | 38499 | 0.0952 | 0.7394 | |
| GSE63941 | DACT2 | 168002 | 1569648_at | 0.2574 | 0.7100 | |
| GSE77861 | DACT2 | 168002 | 1569648_at | -0.0763 | 0.3983 | |
| GSE97050 | DACT2 | 168002 | A_24_P289260 | -0.1556 | 0.8358 | |
| SRP007169 | DACT2 | 168002 | RNAseq | 2.7971 | 0.0000 | |
| SRP133303 | DACT2 | 168002 | RNAseq | -0.3457 | 0.6037 | |
| SRP219564 | DACT2 | 168002 | RNAseq | 1.5659 | 0.0924 | |
| TCGA | DACT2 | 168002 | RNAseq | 0.4599 | 0.3019 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DACT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DACT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DACT2 | 168002 | 2 | 6 | 22 | |
| GSE20123 | DACT2 | 168002 | 2 | 6 | 22 | |
| GSE43470 | DACT2 | 168002 | 3 | 0 | 40 | |
| GSE46452 | DACT2 | 168002 | 3 | 10 | 46 | |
| GSE47630 | DACT2 | 168002 | 7 | 7 | 26 | |
| GSE54993 | DACT2 | 168002 | 4 | 3 | 63 | |
| GSE54994 | DACT2 | 168002 | 10 | 8 | 35 | |
| GSE60625 | DACT2 | 168002 | 1 | 1 | 9 | |
| GSE74703 | DACT2 | 168002 | 3 | 0 | 33 | |
| GSE74704 | DACT2 | 168002 | 1 | 3 | 16 | |
| TCGA | DACT2 | 168002 | 14 | 20 | 62 |
Total number of gains: 50; Total number of losses: 64; Total Number of normals: 374.
Somatic mutations of DACT2:
Generating mutation plots.
Highly correlated genes for DACT2:
Showing top 20/71 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DACT2 | SOX5 | 0.745363 | 3 | 0 | 3 |
| DACT2 | KCNE3 | 0.740469 | 3 | 0 | 3 |
| DACT2 | ATP2A3 | 0.735424 | 3 | 0 | 3 |
| DACT2 | SERPINA5 | 0.727056 | 3 | 0 | 3 |
| DACT2 | C11orf71 | 0.720171 | 3 | 0 | 3 |
| DACT2 | VNN2 | 0.687889 | 3 | 0 | 3 |
| DACT2 | ZMAT4 | 0.681745 | 3 | 0 | 3 |
| DACT2 | TAGAP | 0.673708 | 3 | 0 | 3 |
| DACT2 | HVCN1 | 0.664351 | 3 | 0 | 3 |
| DACT2 | TG | 0.664148 | 3 | 0 | 3 |
| DACT2 | FAM90A1 | 0.661041 | 3 | 0 | 3 |
| DACT2 | MYL2 | 0.658714 | 3 | 0 | 3 |
| DACT2 | GBGT1 | 0.65549 | 3 | 0 | 3 |
| DACT2 | C22orf31 | 0.654289 | 3 | 0 | 3 |
| DACT2 | DUSP19 | 0.653462 | 3 | 0 | 3 |
| DACT2 | FMO4 | 0.647254 | 3 | 0 | 3 |
| DACT2 | SPI1 | 0.646758 | 3 | 0 | 3 |
| DACT2 | C12orf57 | 0.641143 | 4 | 0 | 3 |
| DACT2 | DAP | 0.636504 | 3 | 0 | 3 |
| DACT2 | CMTM2 | 0.635389 | 3 | 0 | 3 |
For details and further investigation, click here
