| Full name: VPS33B late endosome and lysosome associated | Alias Symbol: FLJ14848 | ||
| Type: protein-coding gene | Cytoband: 15q26.1 | ||
| Entrez ID: 26276 | HGNC ID: HGNC:12712 | Ensembl Gene: ENSG00000184056 | OMIM ID: 608552 |
| Drug and gene relationship at DGIdb | |||
Expression of VPS33B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VPS33B | 26276 | 44111_at | -0.1702 | 0.7450 | |
| GSE20347 | VPS33B | 26276 | 44111_at | -0.3548 | 0.0129 | |
| GSE23400 | VPS33B | 26276 | 218415_at | 0.0128 | 0.8134 | |
| GSE26886 | VPS33B | 26276 | 44111_at | -0.2870 | 0.1444 | |
| GSE29001 | VPS33B | 26276 | 44111_at | -0.1658 | 0.4440 | |
| GSE38129 | VPS33B | 26276 | 44111_at | -0.1589 | 0.2136 | |
| GSE45670 | VPS33B | 26276 | 44111_at | 0.0370 | 0.8524 | |
| GSE53622 | VPS33B | 26276 | 92697 | 0.1248 | 0.0031 | |
| GSE53624 | VPS33B | 26276 | 92697 | 0.0233 | 0.7472 | |
| GSE63941 | VPS33B | 26276 | 44111_at | 0.0755 | 0.8720 | |
| GSE77861 | VPS33B | 26276 | 44111_at | -0.2183 | 0.3900 | |
| GSE97050 | VPS33B | 26276 | A_23_P48964 | 0.1229 | 0.6508 | |
| SRP007169 | VPS33B | 26276 | RNAseq | -0.9143 | 0.0164 | |
| SRP008496 | VPS33B | 26276 | RNAseq | -0.9605 | 0.0027 | |
| SRP064894 | VPS33B | 26276 | RNAseq | -0.0762 | 0.4798 | |
| SRP133303 | VPS33B | 26276 | RNAseq | -0.1697 | 0.2882 | |
| SRP159526 | VPS33B | 26276 | RNAseq | -0.1051 | 0.6633 | |
| SRP193095 | VPS33B | 26276 | RNAseq | -0.1383 | 0.1067 | |
| SRP219564 | VPS33B | 26276 | RNAseq | -0.1398 | 0.6653 | |
| TCGA | VPS33B | 26276 | RNAseq | -0.1588 | 0.0071 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by VPS33B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VPS33B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VPS33B | 26276 | 7 | 2 | 21 | |
| GSE20123 | VPS33B | 26276 | 7 | 2 | 21 | |
| GSE43470 | VPS33B | 26276 | 5 | 5 | 33 | |
| GSE46452 | VPS33B | 26276 | 3 | 7 | 49 | |
| GSE47630 | VPS33B | 26276 | 8 | 11 | 21 | |
| GSE54993 | VPS33B | 26276 | 4 | 6 | 60 | |
| GSE54994 | VPS33B | 26276 | 7 | 7 | 39 | |
| GSE60625 | VPS33B | 26276 | 4 | 0 | 7 | |
| GSE74703 | VPS33B | 26276 | 4 | 4 | 28 | |
| GSE74704 | VPS33B | 26276 | 3 | 3 | 14 | |
| TCGA | VPS33B | 26276 | 18 | 12 | 66 |
Total number of gains: 70; Total number of losses: 59; Total Number of normals: 359.
Somatic mutations of VPS33B:
Generating mutation plots.
Highly correlated genes for VPS33B:
Showing top 20/71 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VPS33B | ZDHHC20 | 0.719856 | 3 | 0 | 3 |
| VPS33B | MFSD11 | 0.7071 | 3 | 0 | 3 |
| VPS33B | MVD | 0.705998 | 3 | 0 | 3 |
| VPS33B | CXorf38 | 0.699477 | 3 | 0 | 3 |
| VPS33B | CARD6 | 0.681282 | 3 | 0 | 3 |
| VPS33B | KSR1 | 0.679379 | 3 | 0 | 3 |
| VPS33B | CSNK1G1 | 0.665473 | 3 | 0 | 3 |
| VPS33B | TMEM101 | 0.647674 | 3 | 0 | 3 |
| VPS33B | SLC25A48 | 0.642582 | 3 | 0 | 3 |
| VPS33B | ALOX12B | 0.635394 | 3 | 0 | 3 |
| VPS33B | ESRRA | 0.611571 | 5 | 0 | 4 |
| VPS33B | TBL3 | 0.608472 | 5 | 0 | 3 |
| VPS33B | TMEM125 | 0.604049 | 4 | 0 | 3 |
| VPS33B | CLTCL1 | 0.60329 | 4 | 0 | 3 |
| VPS33B | BAIAP2 | 0.59977 | 4 | 0 | 3 |
| VPS33B | TLCD2 | 0.598306 | 5 | 0 | 4 |
| VPS33B | ENDOG | 0.598167 | 4 | 0 | 3 |
| VPS33B | PERP | 0.59393 | 3 | 0 | 3 |
| VPS33B | SLC35F2 | 0.581316 | 3 | 0 | 3 |
| VPS33B | ENTPD5 | 0.576567 | 6 | 0 | 3 |
For details and further investigation, click here
