| Full name: transducin beta like 3 | Alias Symbol: SAZD|UTP13 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 10607 | HGNC ID: HGNC:11587 | Ensembl Gene: ENSG00000183751 | OMIM ID: 605915 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TBL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBL3 | 10607 | 209820_s_at | 0.0604 | 0.9089 | |
| GSE20347 | TBL3 | 10607 | 209820_s_at | -0.4105 | 0.0010 | |
| GSE23400 | TBL3 | 10607 | 209820_s_at | -0.1481 | 0.0075 | |
| GSE26886 | TBL3 | 10607 | 209820_s_at | 0.0546 | 0.7855 | |
| GSE29001 | TBL3 | 10607 | 209820_s_at | -0.3206 | 0.1880 | |
| GSE38129 | TBL3 | 10607 | 209820_s_at | -0.2686 | 0.0127 | |
| GSE45670 | TBL3 | 10607 | 209820_s_at | -0.0448 | 0.7562 | |
| GSE53622 | TBL3 | 10607 | 22689 | -0.2210 | 0.0334 | |
| GSE53624 | TBL3 | 10607 | 22689 | -0.2803 | 0.0003 | |
| GSE63941 | TBL3 | 10607 | 209820_s_at | 0.4691 | 0.0985 | |
| GSE77861 | TBL3 | 10607 | 209820_s_at | -0.2258 | 0.4412 | |
| GSE97050 | TBL3 | 10607 | A_23_P106720 | 0.2239 | 0.6122 | |
| SRP007169 | TBL3 | 10607 | RNAseq | -1.1596 | 0.0020 | |
| SRP008496 | TBL3 | 10607 | RNAseq | -1.3588 | 0.0000 | |
| SRP064894 | TBL3 | 10607 | RNAseq | -0.0995 | 0.7016 | |
| SRP133303 | TBL3 | 10607 | RNAseq | 0.0220 | 0.9065 | |
| SRP159526 | TBL3 | 10607 | RNAseq | -0.1443 | 0.5531 | |
| SRP193095 | TBL3 | 10607 | RNAseq | -0.0048 | 0.9605 | |
| SRP219564 | TBL3 | 10607 | RNAseq | 0.1266 | 0.7012 | |
| TCGA | TBL3 | 10607 | RNAseq | 0.0693 | 0.1837 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TBL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBL3 | 10607 | 5 | 5 | 20 | |
| GSE20123 | TBL3 | 10607 | 5 | 4 | 21 | |
| GSE43470 | TBL3 | 10607 | 4 | 7 | 32 | |
| GSE46452 | TBL3 | 10607 | 38 | 1 | 20 | |
| GSE47630 | TBL3 | 10607 | 13 | 6 | 21 | |
| GSE54993 | TBL3 | 10607 | 3 | 5 | 62 | |
| GSE54994 | TBL3 | 10607 | 5 | 9 | 39 | |
| GSE60625 | TBL3 | 10607 | 4 | 0 | 7 | |
| GSE74703 | TBL3 | 10607 | 4 | 5 | 27 | |
| GSE74704 | TBL3 | 10607 | 3 | 2 | 15 | |
| TCGA | TBL3 | 10607 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of TBL3:
Generating mutation plots.
Highly correlated genes for TBL3:
Showing top 20/222 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBL3 | ACAT2 | 0.719487 | 3 | 0 | 3 |
| TBL3 | HMOX2 | 0.680722 | 9 | 0 | 8 |
| TBL3 | OLIG3 | 0.677599 | 3 | 0 | 3 |
| TBL3 | ATP6V0C | 0.646892 | 7 | 0 | 6 |
| TBL3 | GID8 | 0.637907 | 8 | 0 | 8 |
| TBL3 | GPN2 | 0.625071 | 5 | 0 | 4 |
| TBL3 | PRMT5 | 0.614969 | 4 | 0 | 3 |
| TBL3 | FAM83G | 0.612896 | 4 | 0 | 3 |
| TBL3 | FBXL16 | 0.611881 | 4 | 0 | 3 |
| TBL3 | ENDOG | 0.611123 | 4 | 0 | 3 |
| TBL3 | VPS33B | 0.608472 | 5 | 0 | 3 |
| TBL3 | NPY2R | 0.607007 | 6 | 0 | 5 |
| TBL3 | AMFR | 0.605473 | 8 | 0 | 6 |
| TBL3 | TMEM45B | 0.604975 | 3 | 0 | 3 |
| TBL3 | LCN8 | 0.602334 | 3 | 0 | 3 |
| TBL3 | RASSF7 | 0.598048 | 8 | 0 | 7 |
| TBL3 | PCYT2 | 0.594433 | 5 | 0 | 4 |
| TBL3 | EME2 | 0.593277 | 4 | 0 | 3 |
| TBL3 | DUOXA2 | 0.59326 | 3 | 0 | 3 |
| TBL3 | GALE | 0.591273 | 10 | 0 | 8 |
For details and further investigation, click here
