| Full name: endonuclease G | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 2021 | HGNC ID: HGNC:3346 | Ensembl Gene: ENSG00000167136 | OMIM ID: 600440 |
| Drug and gene relationship at DGIdb | |||
Expression of ENDOG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ENDOG | 2021 | 204824_at | -0.0522 | 0.9510 | |
| GSE20347 | ENDOG | 2021 | 204824_at | -0.1402 | 0.5575 | |
| GSE23400 | ENDOG | 2021 | 204824_at | -0.0430 | 0.6068 | |
| GSE26886 | ENDOG | 2021 | 204824_at | 0.4141 | 0.1802 | |
| GSE29001 | ENDOG | 2021 | 204824_at | -0.3112 | 0.3625 | |
| GSE38129 | ENDOG | 2021 | 204824_at | -0.0928 | 0.6048 | |
| GSE45670 | ENDOG | 2021 | 204824_at | 0.2382 | 0.2275 | |
| GSE53622 | ENDOG | 2021 | 5479 | -0.0207 | 0.8070 | |
| GSE53624 | ENDOG | 2021 | 5479 | 0.0006 | 0.9951 | |
| GSE63941 | ENDOG | 2021 | 204824_at | 0.5915 | 0.1815 | |
| GSE77861 | ENDOG | 2021 | 204824_at | 0.0087 | 0.9706 | |
| GSE97050 | ENDOG | 2021 | A_23_P83266 | -0.1382 | 0.5664 | |
| SRP007169 | ENDOG | 2021 | RNAseq | -0.0291 | 0.9491 | |
| SRP008496 | ENDOG | 2021 | RNAseq | -0.1241 | 0.6564 | |
| SRP064894 | ENDOG | 2021 | RNAseq | 0.7198 | 0.0915 | |
| SRP133303 | ENDOG | 2021 | RNAseq | -0.1921 | 0.4851 | |
| SRP159526 | ENDOG | 2021 | RNAseq | 0.2870 | 0.3676 | |
| SRP193095 | ENDOG | 2021 | RNAseq | -0.3303 | 0.0343 | |
| SRP219564 | ENDOG | 2021 | RNAseq | -0.1275 | 0.7611 | |
| TCGA | ENDOG | 2021 | RNAseq | -0.0664 | 0.5023 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ENDOG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ENDOG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ENDOG | 2021 | 6 | 9 | 15 | |
| GSE20123 | ENDOG | 2021 | 6 | 9 | 15 | |
| GSE43470 | ENDOG | 2021 | 5 | 8 | 30 | |
| GSE46452 | ENDOG | 2021 | 6 | 13 | 40 | |
| GSE47630 | ENDOG | 2021 | 3 | 16 | 21 | |
| GSE54993 | ENDOG | 2021 | 3 | 3 | 64 | |
| GSE54994 | ENDOG | 2021 | 11 | 8 | 34 | |
| GSE60625 | ENDOG | 2021 | 0 | 0 | 11 | |
| GSE74703 | ENDOG | 2021 | 5 | 6 | 25 | |
| GSE74704 | ENDOG | 2021 | 3 | 7 | 10 | |
| TCGA | ENDOG | 2021 | 27 | 24 | 45 |
Total number of gains: 75; Total number of losses: 103; Total Number of normals: 310.
Somatic mutations of ENDOG:
Generating mutation plots.
Highly correlated genes for ENDOG:
Showing top 20/56 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ENDOG | JMJD8 | 0.825792 | 3 | 0 | 3 |
| ENDOG | NUDT16L1 | 0.682752 | 4 | 0 | 4 |
| ENDOG | PHGR1 | 0.673971 | 4 | 0 | 3 |
| ENDOG | SLITRK1 | 0.668521 | 3 | 0 | 3 |
| ENDOG | GRAP | 0.666979 | 3 | 0 | 3 |
| ENDOG | ANXA1 | 0.660516 | 3 | 0 | 3 |
| ENDOG | PAOX | 0.653357 | 3 | 0 | 3 |
| ENDOG | RPS6KL1 | 0.644705 | 3 | 0 | 3 |
| ENDOG | ACTR3B | 0.635899 | 4 | 0 | 3 |
| ENDOG | HES5 | 0.627679 | 4 | 0 | 3 |
| ENDOG | MRPL23 | 0.627019 | 5 | 0 | 3 |
| ENDOG | RASGEF1A | 0.621842 | 4 | 0 | 3 |
| ENDOG | ZNF48 | 0.621184 | 4 | 0 | 3 |
| ENDOG | NANOS2 | 0.616577 | 4 | 0 | 3 |
| ENDOG | LRRC46 | 0.615404 | 4 | 0 | 3 |
| ENDOG | TBL3 | 0.611123 | 4 | 0 | 3 |
| ENDOG | SRCAP | 0.608382 | 4 | 0 | 4 |
| ENDOG | ACAT2 | 0.60232 | 6 | 0 | 3 |
| ENDOG | MAP6D1 | 0.601967 | 6 | 0 | 5 |
| ENDOG | VPS33B | 0.598167 | 4 | 0 | 3 |
For details and further investigation, click here
