| Full name: WD repeat and FYVE domain containing 3 | Alias Symbol: KIAA0993|ALFY|ZFYVE25 | ||
| Type: protein-coding gene | Cytoband: 4q21.23 | ||
| Entrez ID: 23001 | HGNC ID: HGNC:20751 | Ensembl Gene: ENSG00000163625 | OMIM ID: 617485 |
| Drug and gene relationship at DGIdb | |||
Expression of WDFY3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDFY3 | 23001 | 212602_at | 0.0367 | 0.9307 | |
| GSE20347 | WDFY3 | 23001 | 212602_at | -0.4571 | 0.0006 | |
| GSE23400 | WDFY3 | 23001 | 212606_at | -0.3783 | 0.0000 | |
| GSE26886 | WDFY3 | 23001 | 212602_at | -0.1041 | 0.7326 | |
| GSE29001 | WDFY3 | 23001 | 212602_at | -0.5047 | 0.0739 | |
| GSE38129 | WDFY3 | 23001 | 212602_at | -0.1839 | 0.2924 | |
| GSE45670 | WDFY3 | 23001 | 212606_at | -0.6138 | 0.0001 | |
| GSE53622 | WDFY3 | 23001 | 35084 | -0.6297 | 0.0000 | |
| GSE53624 | WDFY3 | 23001 | 35084 | -0.5763 | 0.0000 | |
| GSE63941 | WDFY3 | 23001 | 212602_at | 0.4712 | 0.2485 | |
| GSE77861 | WDFY3 | 23001 | 212602_at | -0.3606 | 0.0352 | |
| GSE97050 | WDFY3 | 23001 | A_32_P10396 | -0.1852 | 0.4907 | |
| SRP007169 | WDFY3 | 23001 | RNAseq | -0.3010 | 0.4230 | |
| SRP008496 | WDFY3 | 23001 | RNAseq | -0.2610 | 0.2923 | |
| SRP064894 | WDFY3 | 23001 | RNAseq | -0.6660 | 0.0079 | |
| SRP133303 | WDFY3 | 23001 | RNAseq | -0.2193 | 0.2204 | |
| SRP159526 | WDFY3 | 23001 | RNAseq | -0.5174 | 0.0001 | |
| SRP193095 | WDFY3 | 23001 | RNAseq | -0.3943 | 0.0002 | |
| SRP219564 | WDFY3 | 23001 | RNAseq | -0.7090 | 0.0291 | |
| TCGA | WDFY3 | 23001 | RNAseq | -0.1632 | 0.0014 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WDFY3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDFY3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDFY3 | 23001 | 2 | 11 | 17 | |
| GSE20123 | WDFY3 | 23001 | 2 | 11 | 17 | |
| GSE43470 | WDFY3 | 23001 | 0 | 13 | 30 | |
| GSE46452 | WDFY3 | 23001 | 1 | 36 | 22 | |
| GSE47630 | WDFY3 | 23001 | 0 | 20 | 20 | |
| GSE54993 | WDFY3 | 23001 | 8 | 0 | 62 | |
| GSE54994 | WDFY3 | 23001 | 1 | 9 | 43 | |
| GSE60625 | WDFY3 | 23001 | 0 | 0 | 11 | |
| GSE74703 | WDFY3 | 23001 | 0 | 11 | 25 | |
| GSE74704 | WDFY3 | 23001 | 1 | 6 | 13 | |
| TCGA | WDFY3 | 23001 | 11 | 35 | 50 |
Total number of gains: 26; Total number of losses: 152; Total Number of normals: 310.
Somatic mutations of WDFY3:
Generating mutation plots.
Highly correlated genes for WDFY3:
Showing top 20/776 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDFY3 | C10orf88 | 0.737078 | 3 | 0 | 3 |
| WDFY3 | GABPA | 0.720515 | 3 | 0 | 3 |
| WDFY3 | SBF2 | 0.71472 | 4 | 0 | 4 |
| WDFY3 | WDFY3-AS2 | 0.711215 | 4 | 0 | 4 |
| WDFY3 | SH3D19 | 0.707025 | 5 | 0 | 5 |
| WDFY3 | TNFSF12 | 0.705025 | 3 | 0 | 3 |
| WDFY3 | CLEC3B | 0.698049 | 3 | 0 | 3 |
| WDFY3 | SPIN4 | 0.697077 | 3 | 0 | 3 |
| WDFY3 | DVL1 | 0.693179 | 4 | 0 | 4 |
| WDFY3 | GNPTAB | 0.69182 | 3 | 0 | 3 |
| WDFY3 | FRS2 | 0.691048 | 3 | 0 | 3 |
| WDFY3 | ARL6IP5 | 0.686637 | 6 | 0 | 6 |
| WDFY3 | POMT1 | 0.686321 | 3 | 0 | 3 |
| WDFY3 | C5orf24 | 0.685735 | 3 | 0 | 3 |
| WDFY3 | SLAIN2 | 0.683648 | 4 | 0 | 4 |
| WDFY3 | PFDN1 | 0.683148 | 3 | 0 | 3 |
| WDFY3 | RSBN1 | 0.68112 | 4 | 0 | 4 |
| WDFY3 | THAP2 | 0.679682 | 4 | 0 | 4 |
| WDFY3 | PCGF3 | 0.678872 | 4 | 0 | 4 |
| WDFY3 | ZNF844 | 0.678021 | 4 | 0 | 3 |
For details and further investigation, click here
