| Full name: SLAIN motif family member 2 | Alias Symbol: FLJ21611 | ||
| Type: protein-coding gene | Cytoband: 4p11 | ||
| Entrez ID: 57606 | HGNC ID: HGNC:29282 | Ensembl Gene: ENSG00000109171 | OMIM ID: 610492 |
| Drug and gene relationship at DGIdb | |||
Expression of SLAIN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLAIN2 | 57606 | 224845_s_at | -0.4889 | 0.1376 | |
| GSE26886 | SLAIN2 | 57606 | 224844_at | -1.3485 | 0.0000 | |
| GSE45670 | SLAIN2 | 57606 | 224844_at | -0.2859 | 0.0581 | |
| GSE53622 | SLAIN2 | 57606 | 18025 | -1.1045 | 0.0000 | |
| GSE53624 | SLAIN2 | 57606 | 18025 | -1.0476 | 0.0000 | |
| GSE63941 | SLAIN2 | 57606 | 224845_s_at | 0.2526 | 0.4803 | |
| GSE77861 | SLAIN2 | 57606 | 224845_s_at | -0.5834 | 0.0072 | |
| SRP007169 | SLAIN2 | 57606 | RNAseq | -1.3522 | 0.0005 | |
| SRP008496 | SLAIN2 | 57606 | RNAseq | -1.2623 | 0.0000 | |
| SRP064894 | SLAIN2 | 57606 | RNAseq | -0.7341 | 0.0000 | |
| SRP133303 | SLAIN2 | 57606 | RNAseq | -0.2526 | 0.0976 | |
| SRP159526 | SLAIN2 | 57606 | RNAseq | -1.0692 | 0.0000 | |
| SRP193095 | SLAIN2 | 57606 | RNAseq | -0.6802 | 0.0000 | |
| SRP219564 | SLAIN2 | 57606 | RNAseq | -0.9549 | 0.0002 | |
| TCGA | SLAIN2 | 57606 | RNAseq | -0.0527 | 0.2524 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by SLAIN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLAIN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLAIN2 | 57606 | 1 | 15 | 14 | |
| GSE20123 | SLAIN2 | 57606 | 1 | 15 | 14 | |
| GSE43470 | SLAIN2 | 57606 | 0 | 13 | 30 | |
| GSE46452 | SLAIN2 | 57606 | 1 | 37 | 21 | |
| GSE47630 | SLAIN2 | 57606 | 1 | 18 | 21 | |
| GSE54993 | SLAIN2 | 57606 | 7 | 0 | 63 | |
| GSE54994 | SLAIN2 | 57606 | 4 | 9 | 40 | |
| GSE60625 | SLAIN2 | 57606 | 0 | 0 | 11 | |
| GSE74703 | SLAIN2 | 57606 | 0 | 11 | 25 | |
| GSE74704 | SLAIN2 | 57606 | 0 | 9 | 11 | |
| TCGA | SLAIN2 | 57606 | 21 | 34 | 41 |
Total number of gains: 36; Total number of losses: 161; Total Number of normals: 291.
Somatic mutations of SLAIN2:
Generating mutation plots.
Highly correlated genes for SLAIN2:
Showing top 20/936 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLAIN2 | PINK1 | 0.764328 | 3 | 0 | 3 |
| SLAIN2 | EPN3 | 0.750431 | 3 | 0 | 3 |
| SLAIN2 | ITSN2 | 0.741599 | 4 | 0 | 4 |
| SLAIN2 | SNORA68 | 0.734936 | 3 | 0 | 3 |
| SLAIN2 | DENND2C | 0.733724 | 3 | 0 | 3 |
| SLAIN2 | GBP6 | 0.732028 | 3 | 0 | 3 |
| SLAIN2 | DUOXA1 | 0.730826 | 3 | 0 | 3 |
| SLAIN2 | FAM95B1 | 0.730028 | 3 | 0 | 3 |
| SLAIN2 | SPNS2 | 0.723934 | 3 | 0 | 3 |
| SLAIN2 | CLIC3 | 0.722928 | 3 | 0 | 3 |
| SLAIN2 | PADI1 | 0.721605 | 3 | 0 | 3 |
| SLAIN2 | MFSD1 | 0.721017 | 3 | 0 | 3 |
| SLAIN2 | EIF2B4 | 0.720933 | 5 | 0 | 5 |
| SLAIN2 | AMOTL2 | 0.720763 | 5 | 0 | 4 |
| SLAIN2 | RHBDF1 | 0.720185 | 3 | 0 | 3 |
| SLAIN2 | SERPINB3 | 0.716085 | 3 | 0 | 3 |
| SLAIN2 | EPB41L4A | 0.712583 | 3 | 0 | 3 |
| SLAIN2 | IGIP | 0.710407 | 3 | 0 | 3 |
| SLAIN2 | RHOV | 0.710113 | 3 | 0 | 3 |
| SLAIN2 | NCOA1 | 0.709212 | 4 | 0 | 3 |
For details and further investigation, click here
