| Full name: WD repeat domain 19 | Alias Symbol: Pwdmp|KIAA1638|FLJ23127|ORF26|DYF-2|Oseg6|IFT144|NPHP13 | ||
| Type: protein-coding gene | Cytoband: 4p14 | ||
| Entrez ID: 57728 | HGNC ID: HGNC:18340 | Ensembl Gene: ENSG00000157796 | OMIM ID: 608151 |
| Drug and gene relationship at DGIdb | |||
Expression of WDR19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR19 | 57728 | 220917_s_at | -0.1691 | 0.6187 | |
| GSE20347 | WDR19 | 57728 | 220917_s_at | -0.0288 | 0.8935 | |
| GSE23400 | WDR19 | 57728 | 220917_s_at | 0.0947 | 0.1757 | |
| GSE26886 | WDR19 | 57728 | 220917_s_at | 0.2084 | 0.5202 | |
| GSE29001 | WDR19 | 57728 | 220917_s_at | -0.2330 | 0.5167 | |
| GSE38129 | WDR19 | 57728 | 220917_s_at | -0.1428 | 0.4881 | |
| GSE45670 | WDR19 | 57728 | 220917_s_at | -0.3627 | 0.1148 | |
| GSE53622 | WDR19 | 57728 | 6385 | -0.1539 | 0.1480 | |
| GSE53624 | WDR19 | 57728 | 6385 | -0.2078 | 0.0060 | |
| GSE63941 | WDR19 | 57728 | 220917_s_at | -1.9885 | 0.0030 | |
| GSE77861 | WDR19 | 57728 | 220917_s_at | 0.0378 | 0.9243 | |
| GSE97050 | WDR19 | 57728 | A_24_P394368 | 0.1410 | 0.4867 | |
| SRP007169 | WDR19 | 57728 | RNAseq | 0.0362 | 0.9324 | |
| SRP008496 | WDR19 | 57728 | RNAseq | 0.3727 | 0.2884 | |
| SRP064894 | WDR19 | 57728 | RNAseq | 0.1061 | 0.6167 | |
| SRP133303 | WDR19 | 57728 | RNAseq | -0.4809 | 0.0081 | |
| SRP159526 | WDR19 | 57728 | RNAseq | 0.1776 | 0.7029 | |
| SRP193095 | WDR19 | 57728 | RNAseq | -0.1407 | 0.3215 | |
| SRP219564 | WDR19 | 57728 | RNAseq | -0.3523 | 0.2726 | |
| TCGA | WDR19 | 57728 | RNAseq | -0.2228 | 0.0062 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by WDR19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR19 | 57728 | 0 | 16 | 14 | |
| GSE20123 | WDR19 | 57728 | 0 | 16 | 14 | |
| GSE43470 | WDR19 | 57728 | 0 | 15 | 28 | |
| GSE46452 | WDR19 | 57728 | 1 | 36 | 22 | |
| GSE47630 | WDR19 | 57728 | 1 | 19 | 20 | |
| GSE54993 | WDR19 | 57728 | 8 | 0 | 62 | |
| GSE54994 | WDR19 | 57728 | 3 | 10 | 40 | |
| GSE60625 | WDR19 | 57728 | 0 | 0 | 11 | |
| GSE74703 | WDR19 | 57728 | 0 | 12 | 24 | |
| GSE74704 | WDR19 | 57728 | 0 | 9 | 11 | |
| TCGA | WDR19 | 57728 | 11 | 45 | 40 |
Total number of gains: 24; Total number of losses: 178; Total Number of normals: 286.
Somatic mutations of WDR19:
Generating mutation plots.
Highly correlated genes for WDR19:
Showing top 20/238 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR19 | PIP5K1B | 0.739484 | 3 | 0 | 3 |
| WDR19 | ZNF449 | 0.721307 | 3 | 0 | 3 |
| WDR19 | SLC25A37 | 0.714372 | 3 | 0 | 3 |
| WDR19 | ART3 | 0.676188 | 3 | 0 | 3 |
| WDR19 | TMEM181 | 0.671817 | 3 | 0 | 3 |
| WDR19 | USP28 | 0.662757 | 3 | 0 | 3 |
| WDR19 | GALNT11 | 0.659685 | 4 | 0 | 3 |
| WDR19 | CYB5D1 | 0.651895 | 3 | 0 | 3 |
| WDR19 | CCL8 | 0.649157 | 3 | 0 | 3 |
| WDR19 | FGF3 | 0.648563 | 5 | 0 | 4 |
| WDR19 | CMKLR1 | 0.648361 | 3 | 0 | 3 |
| WDR19 | NPTX2 | 0.640377 | 4 | 0 | 3 |
| WDR19 | TAF4B | 0.63145 | 4 | 0 | 3 |
| WDR19 | FRMD3 | 0.62568 | 3 | 0 | 3 |
| WDR19 | TXNDC16 | 0.623079 | 4 | 0 | 3 |
| WDR19 | KLHL21 | 0.620351 | 3 | 0 | 3 |
| WDR19 | PREPL | 0.618155 | 7 | 0 | 6 |
| WDR19 | YPEL1 | 0.617246 | 7 | 0 | 5 |
| WDR19 | HEXA | 0.611441 | 4 | 0 | 3 |
| WDR19 | TPT1-AS1 | 0.61087 | 4 | 0 | 3 |
For details and further investigation, click here
