| Full name: WD repeat domain 72 | Alias Symbol: FLJ38736 | ||
| Type: protein-coding gene | Cytoband: 15q21.3 | ||
| Entrez ID: 256764 | HGNC ID: HGNC:26790 | Ensembl Gene: ENSG00000166415 | OMIM ID: 613214 |
| Drug and gene relationship at DGIdb | |||
Expression of WDR72:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR72 | 256764 | 227174_at | 2.1021 | 0.3854 | |
| GSE26886 | WDR72 | 256764 | 227174_at | 5.6365 | 0.0000 | |
| GSE45670 | WDR72 | 256764 | 227174_at | 3.9504 | 0.0000 | |
| GSE53622 | WDR72 | 256764 | 120304 | 1.7661 | 0.0000 | |
| GSE53624 | WDR72 | 256764 | 120304 | 2.3756 | 0.0000 | |
| GSE63941 | WDR72 | 256764 | 227174_at | 5.4512 | 0.0007 | |
| GSE77861 | WDR72 | 256764 | 227174_at | 4.0226 | 0.0010 | |
| SRP007169 | WDR72 | 256764 | RNAseq | 3.2782 | 0.0002 | |
| SRP008496 | WDR72 | 256764 | RNAseq | 3.1746 | 0.0000 | |
| SRP064894 | WDR72 | 256764 | RNAseq | 3.1029 | 0.0000 | |
| SRP133303 | WDR72 | 256764 | RNAseq | 2.5360 | 0.0000 | |
| SRP159526 | WDR72 | 256764 | RNAseq | 4.8615 | 0.0000 | |
| SRP193095 | WDR72 | 256764 | RNAseq | 3.2912 | 0.0000 | |
| SRP219564 | WDR72 | 256764 | RNAseq | 3.6543 | 0.0000 | |
| TCGA | WDR72 | 256764 | RNAseq | 1.4389 | 0.0000 |
Upregulated datasets: 14; Downregulated datasets: 0.
Survival by WDR72 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR72:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR72 | 256764 | 6 | 3 | 21 | |
| GSE20123 | WDR72 | 256764 | 6 | 3 | 21 | |
| GSE43470 | WDR72 | 256764 | 4 | 1 | 38 | |
| GSE46452 | WDR72 | 256764 | 3 | 7 | 49 | |
| GSE47630 | WDR72 | 256764 | 8 | 10 | 22 | |
| GSE54993 | WDR72 | 256764 | 5 | 6 | 59 | |
| GSE54994 | WDR72 | 256764 | 5 | 8 | 40 | |
| GSE60625 | WDR72 | 256764 | 4 | 0 | 7 | |
| GSE74703 | WDR72 | 256764 | 4 | 1 | 31 | |
| GSE74704 | WDR72 | 256764 | 2 | 3 | 15 | |
| TCGA | WDR72 | 256764 | 10 | 18 | 68 |
Total number of gains: 57; Total number of losses: 60; Total Number of normals: 371.
Somatic mutations of WDR72:
Generating mutation plots.
Highly correlated genes for WDR72:
Showing top 20/1123 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR72 | MTERF3 | 0.775054 | 3 | 0 | 3 |
| WDR72 | IPO9 | 0.748326 | 4 | 0 | 4 |
| WDR72 | MARK1 | 0.740972 | 4 | 0 | 4 |
| WDR72 | CMTM4 | 0.725324 | 3 | 0 | 3 |
| WDR72 | HOXB7 | 0.724491 | 7 | 0 | 7 |
| WDR72 | ARPP19 | 0.723013 | 3 | 0 | 3 |
| WDR72 | KLF13 | 0.716055 | 3 | 0 | 3 |
| WDR72 | TMEM132A | 0.711491 | 3 | 0 | 3 |
| WDR72 | POMZP3 | 0.711243 | 3 | 0 | 3 |
| WDR72 | KAT8 | 0.711031 | 3 | 0 | 3 |
| WDR72 | ENOX2 | 0.707276 | 3 | 0 | 3 |
| WDR72 | OIP5 | 0.706732 | 4 | 0 | 4 |
| WDR72 | RFC4 | 0.706013 | 7 | 0 | 7 |
| WDR72 | TOP2A | 0.704732 | 5 | 0 | 4 |
| WDR72 | DDX10 | 0.703809 | 3 | 0 | 3 |
| WDR72 | ACVR1C | 0.703258 | 4 | 0 | 3 |
| WDR72 | UBE2T | 0.701641 | 7 | 0 | 7 |
| WDR72 | WDR81 | 0.69941 | 3 | 0 | 3 |
| WDR72 | FBRSL1 | 0.697883 | 3 | 0 | 3 |
| WDR72 | MCM7 | 0.697018 | 7 | 0 | 7 |
For details and further investigation, click here
