| Full name: Opa interacting protein 5 | Alias Symbol: MIS18B|hMIS18beta|CT86 | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 11339 | HGNC ID: HGNC:20300 | Ensembl Gene: ENSG00000104147 | OMIM ID: 606020 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of OIP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OIP5 | 11339 | 213599_at | 0.8849 | 0.2496 | |
| GSE20347 | OIP5 | 11339 | 213599_at | 1.4473 | 0.0000 | |
| GSE23400 | OIP5 | 11339 | 213599_at | 0.6896 | 0.0000 | |
| GSE26886 | OIP5 | 11339 | 213599_at | 0.4754 | 0.1987 | |
| GSE29001 | OIP5 | 11339 | 213599_at | 1.0183 | 0.0124 | |
| GSE38129 | OIP5 | 11339 | 213599_at | 1.7771 | 0.0000 | |
| GSE45670 | OIP5 | 11339 | 213599_at | 1.0659 | 0.0002 | |
| GSE63941 | OIP5 | 11339 | 213599_at | 3.1888 | 0.0000 | |
| GSE77861 | OIP5 | 11339 | 213599_at | 0.5633 | 0.2808 | |
| GSE97050 | OIP5 | 11339 | A_23_P379614 | 0.5491 | 0.1903 | |
| SRP007169 | OIP5 | 11339 | RNAseq | 2.9754 | 0.0001 | |
| SRP064894 | OIP5 | 11339 | RNAseq | 1.3028 | 0.0000 | |
| SRP133303 | OIP5 | 11339 | RNAseq | 1.5531 | 0.0000 | |
| SRP159526 | OIP5 | 11339 | RNAseq | 1.2336 | 0.0000 | |
| SRP193095 | OIP5 | 11339 | RNAseq | 0.6653 | 0.0000 | |
| SRP219564 | OIP5 | 11339 | RNAseq | 0.8667 | 0.0659 | |
| TCGA | OIP5 | 11339 | RNAseq | 1.4996 | 0.0000 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by OIP5 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of OIP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OIP5 | 11339 | 3 | 6 | 21 | |
| GSE20123 | OIP5 | 11339 | 3 | 6 | 21 | |
| GSE43470 | OIP5 | 11339 | 4 | 6 | 33 | |
| GSE46452 | OIP5 | 11339 | 3 | 7 | 49 | |
| GSE47630 | OIP5 | 11339 | 8 | 11 | 21 | |
| GSE54993 | OIP5 | 11339 | 4 | 6 | 60 | |
| GSE54994 | OIP5 | 11339 | 5 | 7 | 41 | |
| GSE60625 | OIP5 | 11339 | 4 | 0 | 7 | |
| GSE74703 | OIP5 | 11339 | 4 | 5 | 27 | |
| GSE74704 | OIP5 | 11339 | 2 | 4 | 14 | |
| TCGA | OIP5 | 11339 | 11 | 18 | 67 |
Total number of gains: 51; Total number of losses: 76; Total Number of normals: 361.
Somatic mutations of OIP5:
Generating mutation plots.
Highly correlated genes for OIP5:
Showing top 20/726 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OIP5 | CCNB2 | 0.835418 | 9 | 0 | 9 |
| OIP5 | NUSAP1 | 0.832797 | 10 | 0 | 10 |
| OIP5 | BUB1B | 0.830528 | 11 | 0 | 11 |
| OIP5 | CDC20 | 0.818862 | 9 | 0 | 9 |
| OIP5 | PRC1 | 0.803225 | 10 | 0 | 10 |
| OIP5 | MTFR2 | 0.798507 | 5 | 0 | 5 |
| OIP5 | DDIAS | 0.791564 | 5 | 0 | 5 |
| OIP5 | KNSTRN | 0.789843 | 5 | 0 | 5 |
| OIP5 | CDK1 | 0.780518 | 10 | 0 | 10 |
| OIP5 | CEP55 | 0.777246 | 10 | 0 | 9 |
| OIP5 | CDC6 | 0.776199 | 10 | 0 | 10 |
| OIP5 | BCL2L12 | 0.772113 | 4 | 0 | 4 |
| OIP5 | RAD51AP1 | 0.770573 | 11 | 0 | 11 |
| OIP5 | MTFP1 | 0.769376 | 4 | 0 | 4 |
| OIP5 | KIF15 | 0.763402 | 9 | 0 | 9 |
| OIP5 | KIF11 | 0.763312 | 10 | 0 | 10 |
| OIP5 | BUB1 | 0.762598 | 8 | 0 | 8 |
| OIP5 | KIF23 | 0.761882 | 10 | 0 | 10 |
| OIP5 | HMMR | 0.76174 | 9 | 0 | 9 |
| OIP5 | CDCA5 | 0.761454 | 6 | 0 | 6 |
For details and further investigation, click here
