| Full name: fibroblast growth factor receptor like 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 53834 | HGNC ID: HGNC:3693 | Ensembl Gene: ENSG00000127418 | OMIM ID: 605830 |
| Drug and gene relationship at DGIdb | |||
Expression of FGFRL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FGFRL1 | 53834 | 223321_s_at | 0.1157 | 0.7638 | |
| GSE26886 | FGFRL1 | 53834 | 223321_s_at | 0.4255 | 0.0031 | |
| GSE45670 | FGFRL1 | 53834 | 223321_s_at | -0.0378 | 0.6801 | |
| GSE53622 | FGFRL1 | 53834 | 88100 | 0.2076 | 0.0677 | |
| GSE53624 | FGFRL1 | 53834 | 88100 | 0.3553 | 0.0000 | |
| GSE63941 | FGFRL1 | 53834 | 223321_s_at | 0.1165 | 0.7702 | |
| GSE77861 | FGFRL1 | 53834 | 223321_s_at | 0.0253 | 0.8318 | |
| GSE97050 | FGFRL1 | 53834 | A_23_P92349 | 0.1679 | 0.6965 | |
| SRP007169 | FGFRL1 | 53834 | RNAseq | 0.8292 | 0.1036 | |
| SRP008496 | FGFRL1 | 53834 | RNAseq | 0.8808 | 0.0087 | |
| SRP064894 | FGFRL1 | 53834 | RNAseq | 0.1124 | 0.6889 | |
| SRP133303 | FGFRL1 | 53834 | RNAseq | 0.2445 | 0.3794 | |
| SRP159526 | FGFRL1 | 53834 | RNAseq | 1.1771 | 0.0272 | |
| SRP193095 | FGFRL1 | 53834 | RNAseq | 0.6509 | 0.0403 | |
| TCGA | FGFRL1 | 53834 | RNAseq | -0.3985 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FGFRL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FGFRL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FGFRL1 | 53834 | 0 | 17 | 13 | |
| GSE20123 | FGFRL1 | 53834 | 0 | 15 | 15 | |
| GSE43470 | FGFRL1 | 53834 | 0 | 17 | 26 | |
| GSE46452 | FGFRL1 | 53834 | 1 | 36 | 22 | |
| GSE47630 | FGFRL1 | 53834 | 2 | 19 | 19 | |
| GSE54993 | FGFRL1 | 53834 | 11 | 0 | 59 | |
| GSE54994 | FGFRL1 | 53834 | 3 | 12 | 38 | |
| GSE60625 | FGFRL1 | 53834 | 0 | 0 | 11 | |
| GSE74703 | FGFRL1 | 53834 | 0 | 13 | 23 | |
| GSE74704 | FGFRL1 | 53834 | 0 | 8 | 12 | |
| TCGA | FGFRL1 | 53834 | 9 | 47 | 40 |
Total number of gains: 26; Total number of losses: 184; Total Number of normals: 278.
Somatic mutations of FGFRL1:
Generating mutation plots.
Highly correlated genes for FGFRL1:
Showing top 20/235 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FGFRL1 | SLC39A3 | 0.728083 | 3 | 0 | 3 |
| FGFRL1 | TRIB1 | 0.717646 | 3 | 0 | 3 |
| FGFRL1 | PRICKLE1 | 0.715704 | 3 | 0 | 3 |
| FGFRL1 | WDR86 | 0.715004 | 4 | 0 | 3 |
| FGFRL1 | SLC11A1 | 0.710365 | 3 | 0 | 3 |
| FGFRL1 | SCMH1 | 0.70707 | 3 | 0 | 3 |
| FGFRL1 | ZFP92 | 0.70665 | 3 | 0 | 3 |
| FGFRL1 | CD36 | 0.703542 | 3 | 0 | 3 |
| FGFRL1 | NGF | 0.701464 | 4 | 0 | 4 |
| FGFRL1 | ACTN1 | 0.686568 | 3 | 0 | 3 |
| FGFRL1 | MCAM | 0.682752 | 3 | 0 | 3 |
| FGFRL1 | CORO7 | 0.680383 | 3 | 0 | 3 |
| FGFRL1 | CCS | 0.675024 | 3 | 0 | 3 |
| FGFRL1 | VASP | 0.67252 | 3 | 0 | 3 |
| FGFRL1 | CCDC85B | 0.664777 | 4 | 0 | 3 |
| FGFRL1 | POLR2J | 0.662321 | 3 | 0 | 3 |
| FGFRL1 | HSPA12A | 0.659611 | 4 | 0 | 4 |
| FGFRL1 | RILPL1 | 0.658061 | 3 | 0 | 3 |
| FGFRL1 | ICAM1 | 0.65698 | 4 | 0 | 3 |
| FGFRL1 | G0S2 | 0.655801 | 4 | 0 | 3 |
For details and further investigation, click here
