| Full name: WAP four-disulfide core domain 2 | Alias Symbol: HE4|WAP5|dJ461P17.6|EDDM4 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 10406 | HGNC ID: HGNC:15939 | Ensembl Gene: ENSG00000101443 | OMIM ID: 617548 |
| Drug and gene relationship at DGIdb | |||
Expression of WFDC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WFDC2 | 10406 | 203892_at | 0.2680 | 0.8725 | |
| GSE20347 | WFDC2 | 10406 | 203892_at | -0.1368 | 0.5581 | |
| GSE23400 | WFDC2 | 10406 | 203892_at | -0.2886 | 0.0436 | |
| GSE26886 | WFDC2 | 10406 | 203892_at | 1.4546 | 0.0199 | |
| GSE29001 | WFDC2 | 10406 | 203892_at | 0.0772 | 0.8506 | |
| GSE38129 | WFDC2 | 10406 | 203892_at | 0.0396 | 0.9117 | |
| GSE45670 | WFDC2 | 10406 | 203892_at | -0.5550 | 0.0666 | |
| GSE53622 | WFDC2 | 10406 | 21644 | -0.2628 | 0.4124 | |
| GSE53624 | WFDC2 | 10406 | 21644 | -0.9153 | 0.0001 | |
| GSE63941 | WFDC2 | 10406 | 203892_at | 1.9947 | 0.1874 | |
| GSE77861 | WFDC2 | 10406 | 203892_at | -0.0295 | 0.9239 | |
| GSE97050 | WFDC2 | 10406 | A_23_P218675 | 0.5337 | 0.2630 | |
| SRP064894 | WFDC2 | 10406 | RNAseq | -1.7495 | 0.0403 | |
| SRP133303 | WFDC2 | 10406 | RNAseq | -2.1222 | 0.0004 | |
| SRP159526 | WFDC2 | 10406 | RNAseq | 0.7752 | 0.6051 | |
| SRP219564 | WFDC2 | 10406 | RNAseq | 0.6204 | 0.5768 | |
| TCGA | WFDC2 | 10406 | RNAseq | -0.2472 | 0.5691 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by WFDC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WFDC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WFDC2 | 10406 | 14 | 1 | 15 | |
| GSE20123 | WFDC2 | 10406 | 14 | 1 | 15 | |
| GSE43470 | WFDC2 | 10406 | 12 | 1 | 30 | |
| GSE46452 | WFDC2 | 10406 | 29 | 0 | 30 | |
| GSE47630 | WFDC2 | 10406 | 24 | 1 | 15 | |
| GSE54993 | WFDC2 | 10406 | 0 | 17 | 53 | |
| GSE54994 | WFDC2 | 10406 | 25 | 0 | 28 | |
| GSE60625 | WFDC2 | 10406 | 0 | 0 | 11 | |
| GSE74703 | WFDC2 | 10406 | 10 | 1 | 25 | |
| GSE74704 | WFDC2 | 10406 | 10 | 0 | 10 | |
| TCGA | WFDC2 | 10406 | 45 | 3 | 48 |
Total number of gains: 183; Total number of losses: 25; Total Number of normals: 280.
Somatic mutations of WFDC2:
Generating mutation plots.
Highly correlated genes for WFDC2:
Showing top 20/60 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WFDC2 | RLN1 | 0.707466 | 3 | 0 | 3 |
| WFDC2 | EYA1 | 0.648986 | 4 | 0 | 3 |
| WFDC2 | GLYATL2 | 0.635807 | 5 | 0 | 5 |
| WFDC2 | CRABP1 | 0.620406 | 4 | 0 | 4 |
| WFDC2 | AZGP1 | 0.617103 | 9 | 0 | 7 |
| WFDC2 | PROM1 | 0.616036 | 10 | 0 | 8 |
| WFDC2 | VTCN1 | 0.608421 | 7 | 0 | 5 |
| WFDC2 | AGR2 | 0.606521 | 8 | 0 | 7 |
| WFDC2 | NXPE4 | 0.604899 | 4 | 0 | 3 |
| WFDC2 | SLC34A2 | 0.604703 | 6 | 0 | 4 |
| WFDC2 | NPTX2 | 0.601324 | 4 | 0 | 4 |
| WFDC2 | AGR3 | 0.596746 | 6 | 0 | 5 |
| WFDC2 | FDCSP | 0.593061 | 5 | 0 | 4 |
| WFDC2 | RARRES1 | 0.591133 | 5 | 0 | 3 |
| WFDC2 | ENPP5 | 0.586545 | 6 | 0 | 4 |
| WFDC2 | SCGB3A1 | 0.586513 | 8 | 0 | 5 |
| WFDC2 | BPIFB1 | 0.583548 | 8 | 0 | 6 |
| WFDC2 | CP | 0.582182 | 9 | 0 | 7 |
| WFDC2 | CDH12 | 0.576302 | 6 | 0 | 4 |
| WFDC2 | ZG16B | 0.570847 | 8 | 0 | 5 |
For details and further investigation, click here
