| Full name: sprouty related EVH1 domain containing 2 | Alias Symbol: Spred-2|FLJ21897|FLJ31917 | ||
| Type: protein-coding gene | Cytoband: 2p14 | ||
| Entrez ID: 200734 | HGNC ID: HGNC:17722 | Ensembl Gene: ENSG00000198369 | OMIM ID: 609292 |
| Drug and gene relationship at DGIdb | |||
Expression of SPRED2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPRED2 | 200734 | 212458_at | 0.1486 | 0.8478 | |
| GSE20347 | SPRED2 | 200734 | 212458_at | 0.5522 | 0.0416 | |
| GSE23400 | SPRED2 | 200734 | 212458_at | 0.4622 | 0.0000 | |
| GSE26886 | SPRED2 | 200734 | 212458_at | 0.5955 | 0.0091 | |
| GSE29001 | SPRED2 | 200734 | 212458_at | 0.1707 | 0.6520 | |
| GSE38129 | SPRED2 | 200734 | 212458_at | 0.3466 | 0.0892 | |
| GSE45670 | SPRED2 | 200734 | 212458_at | -0.1463 | 0.5018 | |
| GSE53622 | SPRED2 | 200734 | 53932 | 0.6253 | 0.0000 | |
| GSE53624 | SPRED2 | 200734 | 53932 | 0.4076 | 0.0000 | |
| GSE63941 | SPRED2 | 200734 | 212458_at | -0.6102 | 0.3031 | |
| GSE77861 | SPRED2 | 200734 | 212458_at | 0.6625 | 0.0326 | |
| GSE97050 | SPRED2 | 200734 | A_32_P225854 | 0.5160 | 0.1042 | |
| SRP007169 | SPRED2 | 200734 | RNAseq | 0.8456 | 0.0414 | |
| SRP008496 | SPRED2 | 200734 | RNAseq | 0.5933 | 0.0220 | |
| SRP064894 | SPRED2 | 200734 | RNAseq | 0.0965 | 0.6748 | |
| SRP133303 | SPRED2 | 200734 | RNAseq | 0.4529 | 0.0473 | |
| SRP159526 | SPRED2 | 200734 | RNAseq | 0.9730 | 0.0155 | |
| SRP193095 | SPRED2 | 200734 | RNAseq | 0.0669 | 0.6894 | |
| SRP219564 | SPRED2 | 200734 | RNAseq | -0.0147 | 0.9652 | |
| TCGA | SPRED2 | 200734 | RNAseq | -0.0430 | 0.4380 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPRED2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPRED2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPRED2 | 200734 | 12 | 0 | 18 | |
| GSE20123 | SPRED2 | 200734 | 12 | 0 | 18 | |
| GSE43470 | SPRED2 | 200734 | 6 | 1 | 36 | |
| GSE46452 | SPRED2 | 200734 | 2 | 3 | 54 | |
| GSE47630 | SPRED2 | 200734 | 8 | 0 | 32 | |
| GSE54993 | SPRED2 | 200734 | 0 | 6 | 64 | |
| GSE54994 | SPRED2 | 200734 | 12 | 0 | 41 | |
| GSE60625 | SPRED2 | 200734 | 0 | 3 | 8 | |
| GSE74703 | SPRED2 | 200734 | 6 | 1 | 29 | |
| GSE74704 | SPRED2 | 200734 | 10 | 0 | 10 | |
| TCGA | SPRED2 | 200734 | 36 | 2 | 58 |
Total number of gains: 104; Total number of losses: 16; Total Number of normals: 368.
Somatic mutations of SPRED2:
Generating mutation plots.
Highly correlated genes for SPRED2:
Showing top 20/777 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPRED2 | RNF26 | 0.811583 | 3 | 0 | 3 |
| SPRED2 | BPGM | 0.784736 | 3 | 0 | 3 |
| SPRED2 | ABCF2 | 0.765824 | 3 | 0 | 3 |
| SPRED2 | RBMX2 | 0.760848 | 3 | 0 | 3 |
| SPRED2 | DNMBP | 0.757587 | 4 | 0 | 4 |
| SPRED2 | XPO4 | 0.752784 | 3 | 0 | 3 |
| SPRED2 | WEE1 | 0.741994 | 3 | 0 | 3 |
| SPRED2 | ADAM10 | 0.73247 | 3 | 0 | 3 |
| SPRED2 | SFT2D3 | 0.73102 | 5 | 0 | 5 |
| SPRED2 | FAM199X | 0.730967 | 3 | 0 | 3 |
| SPRED2 | TMTC3 | 0.727582 | 3 | 0 | 3 |
| SPRED2 | CCNT1 | 0.714714 | 3 | 0 | 3 |
| SPRED2 | CREB5 | 0.711669 | 4 | 0 | 3 |
| SPRED2 | ADAM9 | 0.709599 | 3 | 0 | 3 |
| SPRED2 | EFTUD2 | 0.709177 | 3 | 0 | 3 |
| SPRED2 | MAP3K11 | 0.708277 | 3 | 0 | 3 |
| SPRED2 | ZFX | 0.708096 | 3 | 0 | 3 |
| SPRED2 | ZNF664 | 0.705553 | 3 | 0 | 3 |
| SPRED2 | BMP2 | 0.703243 | 4 | 0 | 4 |
| SPRED2 | PKIG | 0.701844 | 3 | 0 | 3 |
For details and further investigation, click here
