| Full name: yippee like 5 | Alias Symbol: CGI-127 | ||
| Type: protein-coding gene | Cytoband: 2p23.1 | ||
| Entrez ID: 51646 | HGNC ID: HGNC:18329 | Ensembl Gene: ENSG00000119801 | OMIM ID: 609726 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of YPEL5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | YPEL5 | 51646 | 217783_s_at | -0.3161 | 0.4498 | |
| GSE20347 | YPEL5 | 51646 | 217783_s_at | -0.4262 | 0.0029 | |
| GSE23400 | YPEL5 | 51646 | 217783_s_at | -0.2701 | 0.0016 | |
| GSE26886 | YPEL5 | 51646 | 217783_s_at | 0.1559 | 0.3431 | |
| GSE29001 | YPEL5 | 51646 | 217783_s_at | -0.2329 | 0.4404 | |
| GSE38129 | YPEL5 | 51646 | 217783_s_at | -0.5953 | 0.0001 | |
| GSE45670 | YPEL5 | 51646 | 222408_s_at | -0.2394 | 0.1786 | |
| GSE53622 | YPEL5 | 51646 | 52852 | -0.4578 | 0.0000 | |
| GSE53624 | YPEL5 | 51646 | 52852 | -0.7158 | 0.0000 | |
| GSE63941 | YPEL5 | 51646 | 222408_s_at | -0.6367 | 0.2131 | |
| GSE77861 | YPEL5 | 51646 | 222408_s_at | -0.2866 | 0.3244 | |
| GSE97050 | YPEL5 | 51646 | A_23_P108835 | -0.3902 | 0.3051 | |
| SRP007169 | YPEL5 | 51646 | RNAseq | -1.7591 | 0.0000 | |
| SRP008496 | YPEL5 | 51646 | RNAseq | -1.3722 | 0.0000 | |
| SRP064894 | YPEL5 | 51646 | RNAseq | -0.5354 | 0.0002 | |
| SRP133303 | YPEL5 | 51646 | RNAseq | -0.1463 | 0.2254 | |
| SRP159526 | YPEL5 | 51646 | RNAseq | -0.2338 | 0.5285 | |
| SRP193095 | YPEL5 | 51646 | RNAseq | -0.4453 | 0.0026 | |
| SRP219564 | YPEL5 | 51646 | RNAseq | -0.2877 | 0.2991 | |
| TCGA | YPEL5 | 51646 | RNAseq | -0.0462 | 0.3114 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by YPEL5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of YPEL5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | YPEL5 | 51646 | 11 | 1 | 18 | |
| GSE20123 | YPEL5 | 51646 | 9 | 1 | 20 | |
| GSE43470 | YPEL5 | 51646 | 2 | 1 | 40 | |
| GSE46452 | YPEL5 | 51646 | 2 | 4 | 53 | |
| GSE47630 | YPEL5 | 51646 | 8 | 0 | 32 | |
| GSE54993 | YPEL5 | 51646 | 0 | 6 | 64 | |
| GSE54994 | YPEL5 | 51646 | 10 | 0 | 43 | |
| GSE60625 | YPEL5 | 51646 | 0 | 3 | 8 | |
| GSE74703 | YPEL5 | 51646 | 2 | 0 | 34 | |
| GSE74704 | YPEL5 | 51646 | 9 | 1 | 10 | |
| TCGA | YPEL5 | 51646 | 36 | 2 | 58 |
Total number of gains: 89; Total number of losses: 19; Total Number of normals: 380.
Somatic mutations of YPEL5:
Generating mutation plots.
Highly correlated genes for YPEL5:
Showing top 20/734 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| YPEL5 | ZCCHC10 | 0.766987 | 3 | 0 | 3 |
| YPEL5 | STARD9 | 0.736488 | 3 | 0 | 3 |
| YPEL5 | PRDM8 | 0.724041 | 3 | 0 | 3 |
| YPEL5 | RASD2 | 0.712157 | 3 | 0 | 3 |
| YPEL5 | TAF9B | 0.707277 | 3 | 0 | 3 |
| YPEL5 | DYNLL2 | 0.706877 | 4 | 0 | 4 |
| YPEL5 | RGS7BP | 0.706053 | 4 | 0 | 3 |
| YPEL5 | CCDC136 | 0.705068 | 3 | 0 | 3 |
| YPEL5 | RNASE4 | 0.702101 | 6 | 0 | 5 |
| YPEL5 | SLC12A6 | 0.695334 | 3 | 0 | 3 |
| YPEL5 | EBF2 | 0.687169 | 4 | 0 | 3 |
| YPEL5 | FOXN3 | 0.686952 | 4 | 0 | 3 |
| YPEL5 | TSPAN18 | 0.685951 | 3 | 0 | 3 |
| YPEL5 | ERLEC1 | 0.681235 | 3 | 0 | 3 |
| YPEL5 | RGS9 | 0.678699 | 5 | 0 | 4 |
| YPEL5 | STK40 | 0.674321 | 4 | 0 | 3 |
| YPEL5 | RIMKLB | 0.671548 | 3 | 0 | 3 |
| YPEL5 | CTDSP1 | 0.664563 | 3 | 0 | 3 |
| YPEL5 | LYRM7 | 0.66351 | 3 | 0 | 3 |
| YPEL5 | FNBP1 | 0.657998 | 7 | 0 | 6 |
For details and further investigation, click here
