| Full name: zinc finger and BTB domain containing 18 | Alias Symbol: C2H2-171|TAZ-1|RP58 | ||
| Type: protein-coding gene | Cytoband: 1q44 | ||
| Entrez ID: 10472 | HGNC ID: HGNC:13030 | Ensembl Gene: ENSG00000179456 | OMIM ID: 608433 |
| Drug and gene relationship at DGIdb | |||
Expression of ZBTB18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB18 | 10472 | 212774_at | 0.3999 | 0.5730 | |
| GSE20347 | ZBTB18 | 10472 | 212774_at | 0.2556 | 0.3256 | |
| GSE23400 | ZBTB18 | 10472 | 212774_at | 0.2442 | 0.1727 | |
| GSE26886 | ZBTB18 | 10472 | 212774_at | 0.4709 | 0.2049 | |
| GSE29001 | ZBTB18 | 10472 | 212774_at | 0.2238 | 0.6303 | |
| GSE38129 | ZBTB18 | 10472 | 212774_at | 0.0925 | 0.6903 | |
| GSE45670 | ZBTB18 | 10472 | 212774_at | -0.1615 | 0.7836 | |
| GSE53622 | ZBTB18 | 10472 | 5201 | -0.2642 | 0.0396 | |
| GSE53624 | ZBTB18 | 10472 | 5201 | -0.0957 | 0.4601 | |
| GSE63941 | ZBTB18 | 10472 | 212774_at | -0.8438 | 0.3894 | |
| GSE77861 | ZBTB18 | 10472 | 212774_at | 0.5308 | 0.2127 | |
| SRP007169 | ZBTB18 | 10472 | RNAseq | 1.2067 | 0.0362 | |
| SRP064894 | ZBTB18 | 10472 | RNAseq | -0.0527 | 0.8412 | |
| SRP133303 | ZBTB18 | 10472 | RNAseq | 0.3289 | 0.4465 | |
| SRP159526 | ZBTB18 | 10472 | RNAseq | 0.3687 | 0.1681 | |
| SRP193095 | ZBTB18 | 10472 | RNAseq | 0.0140 | 0.9430 | |
| SRP219564 | ZBTB18 | 10472 | RNAseq | 0.1392 | 0.7090 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZBTB18 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ZBTB18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB18 | 10472 | 7 | 1 | 22 | |
| GSE20123 | ZBTB18 | 10472 | 7 | 1 | 22 | |
| GSE43470 | ZBTB18 | 10472 | 6 | 2 | 35 | |
| GSE46452 | ZBTB18 | 10472 | 4 | 2 | 53 | |
| GSE47630 | ZBTB18 | 10472 | 15 | 0 | 25 | |
| GSE54993 | ZBTB18 | 10472 | 1 | 6 | 63 | |
| GSE54994 | ZBTB18 | 10472 | 18 | 0 | 35 | |
| GSE60625 | ZBTB18 | 10472 | 0 | 0 | 11 | |
| GSE74703 | ZBTB18 | 10472 | 6 | 1 | 29 | |
| GSE74704 | ZBTB18 | 10472 | 2 | 0 | 18 | |
| TCGA | ZBTB18 | 10472 | 45 | 4 | 47 |
Total number of gains: 111; Total number of losses: 17; Total Number of normals: 360.
Somatic mutations of ZBTB18:
Generating mutation plots.
Highly correlated genes for ZBTB18:
Showing top 20/92 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB18 | ZNF260 | 0.732269 | 3 | 0 | 3 |
| ZBTB18 | ZBTB44 | 0.690776 | 3 | 0 | 3 |
| ZBTB18 | HELZ | 0.650946 | 3 | 0 | 3 |
| ZBTB18 | USP20 | 0.635789 | 4 | 0 | 3 |
| ZBTB18 | NCOA5 | 0.630493 | 3 | 0 | 3 |
| ZBTB18 | TFB2M | 0.627682 | 3 | 0 | 3 |
| ZBTB18 | ATP6V0E2 | 0.622881 | 6 | 0 | 4 |
| ZBTB18 | NUB1 | 0.616123 | 3 | 0 | 3 |
| ZBTB18 | PIK3R3 | 0.614566 | 9 | 0 | 6 |
| ZBTB18 | NLK | 0.614379 | 6 | 0 | 5 |
| ZBTB18 | LRIG1 | 0.613115 | 9 | 0 | 7 |
| ZBTB18 | DTNBP1 | 0.603633 | 4 | 0 | 3 |
| ZBTB18 | SBK1 | 0.5959 | 5 | 0 | 4 |
| ZBTB18 | NNT-AS1 | 0.593742 | 3 | 0 | 3 |
| ZBTB18 | BRD3 | 0.593099 | 4 | 0 | 3 |
| ZBTB18 | ATXN7L3B | 0.592382 | 4 | 0 | 3 |
| ZBTB18 | ZNF507 | 0.592002 | 3 | 0 | 3 |
| ZBTB18 | LINC01234 | 0.588374 | 3 | 0 | 3 |
| ZBTB18 | PRAME | 0.581924 | 4 | 0 | 3 |
| ZBTB18 | ASF1A | 0.578969 | 3 | 0 | 3 |
For details and further investigation, click here
