| Full name: DnaJ heat shock protein family (Hsp40) member A2 | Alias Symbol: HIRIP4|DNAJ|CPR3|DNJ3 | ||
| Type: protein-coding gene | Cytoband: 16q11.2 | ||
| Entrez ID: 10294 | HGNC ID: HGNC:14884 | Ensembl Gene: ENSG00000069345 | OMIM ID: 611322 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DNAJA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJA2 | 10294 | 209157_at | -0.2597 | 0.5859 | |
| GSE20347 | DNAJA2 | 10294 | 209157_at | -0.5058 | 0.0042 | |
| GSE23400 | DNAJA2 | 10294 | 209157_at | -0.2811 | 0.0002 | |
| GSE26886 | DNAJA2 | 10294 | 209157_at | -1.3070 | 0.0000 | |
| GSE29001 | DNAJA2 | 10294 | 209157_at | -0.6546 | 0.1028 | |
| GSE38129 | DNAJA2 | 10294 | 209157_at | -0.2420 | 0.1187 | |
| GSE45670 | DNAJA2 | 10294 | 209157_at | -0.1159 | 0.2693 | |
| GSE53622 | DNAJA2 | 10294 | 113135 | -0.9356 | 0.0000 | |
| GSE53624 | DNAJA2 | 10294 | 113135 | -0.8864 | 0.0000 | |
| GSE63941 | DNAJA2 | 10294 | 209157_at | 0.0929 | 0.8060 | |
| GSE77861 | DNAJA2 | 10294 | 209157_at | -0.3069 | 0.2724 | |
| GSE97050 | DNAJA2 | 10294 | A_33_P3414574 | -0.8422 | 0.0555 | |
| SRP007169 | DNAJA2 | 10294 | RNAseq | -0.9163 | 0.0046 | |
| SRP008496 | DNAJA2 | 10294 | RNAseq | -0.9020 | 0.0001 | |
| SRP064894 | DNAJA2 | 10294 | RNAseq | -0.6926 | 0.0000 | |
| SRP133303 | DNAJA2 | 10294 | RNAseq | -0.1024 | 0.3856 | |
| SRP159526 | DNAJA2 | 10294 | RNAseq | -0.1865 | 0.5228 | |
| SRP193095 | DNAJA2 | 10294 | RNAseq | -0.4331 | 0.0005 | |
| SRP219564 | DNAJA2 | 10294 | RNAseq | -0.7250 | 0.0075 | |
| TCGA | DNAJA2 | 10294 | RNAseq | -0.0224 | 0.6192 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DNAJA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJA2 | 10294 | 2 | 1 | 27 | |
| GSE20123 | DNAJA2 | 10294 | 2 | 1 | 27 | |
| GSE43470 | DNAJA2 | 10294 | 2 | 7 | 34 | |
| GSE46452 | DNAJA2 | 10294 | 38 | 1 | 20 | |
| GSE47630 | DNAJA2 | 10294 | 11 | 7 | 22 | |
| GSE54993 | DNAJA2 | 10294 | 2 | 5 | 63 | |
| GSE54994 | DNAJA2 | 10294 | 6 | 10 | 37 | |
| GSE60625 | DNAJA2 | 10294 | 4 | 0 | 7 | |
| GSE74703 | DNAJA2 | 10294 | 2 | 4 | 30 | |
| GSE74704 | DNAJA2 | 10294 | 2 | 1 | 17 | |
| TCGA | DNAJA2 | 10294 | 29 | 11 | 56 |
Total number of gains: 100; Total number of losses: 48; Total Number of normals: 340.
Somatic mutations of DNAJA2:
Generating mutation plots.
Highly correlated genes for DNAJA2:
Showing top 20/1232 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJA2 | CHCHD4 | 0.79737 | 3 | 0 | 3 |
| DNAJA2 | MTIF3 | 0.794305 | 3 | 0 | 3 |
| DNAJA2 | MRPL30 | 0.767189 | 3 | 0 | 3 |
| DNAJA2 | TRAPPC2 | 0.763356 | 3 | 0 | 3 |
| DNAJA2 | ANGPTL1 | 0.752558 | 3 | 0 | 3 |
| DNAJA2 | CLEC3B | 0.750336 | 3 | 0 | 3 |
| DNAJA2 | SNX14 | 0.746174 | 3 | 0 | 3 |
| DNAJA2 | TANC1 | 0.730345 | 3 | 0 | 3 |
| DNAJA2 | PPP2R5E | 0.729676 | 4 | 0 | 4 |
| DNAJA2 | ZCCHC9 | 0.728116 | 4 | 0 | 3 |
| DNAJA2 | TMCC3 | 0.727095 | 3 | 0 | 3 |
| DNAJA2 | ZBTB8OS | 0.723959 | 3 | 0 | 3 |
| DNAJA2 | DCAF12 | 0.722845 | 3 | 0 | 3 |
| DNAJA2 | PTGR1 | 0.721077 | 5 | 0 | 4 |
| DNAJA2 | CYP2C19 | 0.720393 | 3 | 0 | 3 |
| DNAJA2 | DCAF8 | 0.718447 | 3 | 0 | 3 |
| DNAJA2 | TMEM50A | 0.718392 | 3 | 0 | 3 |
| DNAJA2 | TMUB2 | 0.718349 | 3 | 0 | 3 |
| DNAJA2 | BARD1 | 0.71789 | 3 | 0 | 3 |
| DNAJA2 | RRAGC | 0.713836 | 3 | 0 | 3 |
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