| Full name: chromosome 11 open reading frame 80 | Alias Symbol: FLJ22531|TOPOVIBL | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 79703 | HGNC ID: HGNC:26197 | Ensembl Gene: ENSG00000173715 | OMIM ID: 616109 |
| Drug and gene relationship at DGIdb | |||
Expression of C11orf80:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C11orf80 | 79703 | 204922_at | 0.2372 | 0.6830 | |
| GSE20347 | C11orf80 | 79703 | 204922_at | -0.4058 | 0.0441 | |
| GSE23400 | C11orf80 | 79703 | 204922_at | -0.0712 | 0.4072 | |
| GSE26886 | C11orf80 | 79703 | 204922_at | 0.0811 | 0.7337 | |
| GSE29001 | C11orf80 | 79703 | 204922_at | -0.4530 | 0.2340 | |
| GSE38129 | C11orf80 | 79703 | 204922_at | -0.0241 | 0.9225 | |
| GSE45670 | C11orf80 | 79703 | 238593_at | 0.5813 | 0.0091 | |
| GSE53622 | C11orf80 | 79703 | 31060 | 0.2802 | 0.0615 | |
| GSE53624 | C11orf80 | 79703 | 31060 | -0.1594 | 0.3141 | |
| GSE63941 | C11orf80 | 79703 | 238593_at | 2.7641 | 0.0062 | |
| GSE77861 | C11orf80 | 79703 | 204922_at | 0.0338 | 0.8859 | |
| GSE97050 | C11orf80 | 79703 | A_23_P96165 | 0.4646 | 0.4233 | |
| SRP007169 | C11orf80 | 79703 | RNAseq | -1.0573 | 0.0180 | |
| SRP008496 | C11orf80 | 79703 | RNAseq | -0.8286 | 0.0124 | |
| SRP064894 | C11orf80 | 79703 | RNAseq | -0.1098 | 0.6261 | |
| SRP133303 | C11orf80 | 79703 | RNAseq | 0.1891 | 0.3292 | |
| SRP159526 | C11orf80 | 79703 | RNAseq | -0.5685 | 0.0036 | |
| SRP193095 | C11orf80 | 79703 | RNAseq | -0.2694 | 0.1241 | |
| SRP219564 | C11orf80 | 79703 | RNAseq | 0.1767 | 0.7625 | |
| TCGA | C11orf80 | 79703 | RNAseq | 0.5975 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by C11orf80 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C11orf80:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C11orf80 | 79703 | 9 | 3 | 18 | |
| GSE20123 | C11orf80 | 79703 | 9 | 3 | 18 | |
| GSE43470 | C11orf80 | 79703 | 6 | 1 | 36 | |
| GSE46452 | C11orf80 | 79703 | 12 | 3 | 44 | |
| GSE47630 | C11orf80 | 79703 | 9 | 4 | 27 | |
| GSE54993 | C11orf80 | 79703 | 3 | 0 | 67 | |
| GSE54994 | C11orf80 | 79703 | 10 | 7 | 36 | |
| GSE60625 | C11orf80 | 79703 | 0 | 3 | 8 | |
| GSE74703 | C11orf80 | 79703 | 4 | 0 | 32 | |
| GSE74704 | C11orf80 | 79703 | 7 | 1 | 12 | |
| TCGA | C11orf80 | 79703 | 24 | 9 | 63 |
Total number of gains: 93; Total number of losses: 34; Total Number of normals: 361.
Somatic mutations of C11orf80:
Generating mutation plots.
Highly correlated genes for C11orf80:
Showing top 20/430 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C11orf80 | LMBR1 | 0.753674 | 3 | 0 | 3 |
| C11orf80 | NIPBL | 0.749798 | 3 | 0 | 3 |
| C11orf80 | PMF1 | 0.746499 | 3 | 0 | 3 |
| C11orf80 | MPV17L | 0.743781 | 3 | 0 | 3 |
| C11orf80 | ZBTB8OS | 0.734599 | 3 | 0 | 3 |
| C11orf80 | MTIF2 | 0.733404 | 3 | 0 | 3 |
| C11orf80 | MRPL35 | 0.712694 | 3 | 0 | 3 |
| C11orf80 | DVL1 | 0.711974 | 3 | 0 | 3 |
| C11orf80 | RSBN1 | 0.711328 | 3 | 0 | 3 |
| C11orf80 | TGFB1 | 0.705989 | 3 | 0 | 3 |
| C11orf80 | CPNE2 | 0.702127 | 3 | 0 | 3 |
| C11orf80 | HSPA4L | 0.70159 | 3 | 0 | 3 |
| C11orf80 | EBPL | 0.70082 | 3 | 0 | 3 |
| C11orf80 | CEP76 | 0.698394 | 3 | 0 | 3 |
| C11orf80 | DHTKD1 | 0.695321 | 4 | 0 | 4 |
| C11orf80 | INO80E | 0.690705 | 3 | 0 | 3 |
| C11orf80 | IRAK4 | 0.689234 | 3 | 0 | 3 |
| C11orf80 | DIP2B | 0.687532 | 4 | 0 | 4 |
| C11orf80 | RMI1 | 0.686417 | 3 | 0 | 3 |
| C11orf80 | AFG3L2 | 0.685118 | 3 | 0 | 3 |
For details and further investigation, click here
