| Full name: G elongation factor mitochondrial 2 | Alias Symbol: EFG2|FLJ21661|EF-G2mt | ||
| Type: protein-coding gene | Cytoband: 5q13.3 | ||
| Entrez ID: 84340 | HGNC ID: HGNC:29682 | Ensembl Gene: ENSG00000164347 | OMIM ID: 606544 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GFM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GFM2 | 84340 | 225392_at | -0.0160 | 0.9799 | |
| GSE26886 | GFM2 | 84340 | 225392_at | -0.0480 | 0.8477 | |
| GSE45670 | GFM2 | 84340 | 225392_at | 0.1306 | 0.3102 | |
| GSE53622 | GFM2 | 84340 | 96294 | 0.2239 | 0.0007 | |
| GSE53624 | GFM2 | 84340 | 61174 | -0.0271 | 0.7040 | |
| GSE63941 | GFM2 | 84340 | 225392_at | 0.4146 | 0.1997 | |
| GSE77861 | GFM2 | 84340 | 225392_at | -0.1885 | 0.5090 | |
| GSE97050 | GFM2 | 84340 | A_24_P137582 | 0.3803 | 0.1934 | |
| SRP007169 | GFM2 | 84340 | RNAseq | -0.1075 | 0.7646 | |
| SRP008496 | GFM2 | 84340 | RNAseq | -0.2791 | 0.2437 | |
| SRP064894 | GFM2 | 84340 | RNAseq | -0.1627 | 0.3136 | |
| SRP133303 | GFM2 | 84340 | RNAseq | 0.1133 | 0.4452 | |
| SRP159526 | GFM2 | 84340 | RNAseq | 0.1687 | 0.6132 | |
| SRP193095 | GFM2 | 84340 | RNAseq | -0.3522 | 0.0022 | |
| SRP219564 | GFM2 | 84340 | RNAseq | -0.3788 | 0.2848 | |
| TCGA | GFM2 | 84340 | RNAseq | -0.1156 | 0.0289 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GFM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GFM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GFM2 | 84340 | 1 | 13 | 16 | |
| GSE20123 | GFM2 | 84340 | 1 | 13 | 16 | |
| GSE43470 | GFM2 | 84340 | 1 | 13 | 29 | |
| GSE46452 | GFM2 | 84340 | 0 | 28 | 31 | |
| GSE47630 | GFM2 | 84340 | 1 | 19 | 20 | |
| GSE54993 | GFM2 | 84340 | 8 | 1 | 61 | |
| GSE54994 | GFM2 | 84340 | 1 | 19 | 33 | |
| GSE60625 | GFM2 | 84340 | 0 | 0 | 11 | |
| GSE74703 | GFM2 | 84340 | 1 | 9 | 26 | |
| GSE74704 | GFM2 | 84340 | 1 | 6 | 13 | |
| TCGA | GFM2 | 84340 | 4 | 50 | 42 |
Total number of gains: 19; Total number of losses: 171; Total Number of normals: 298.
Somatic mutations of GFM2:
Generating mutation plots.
Highly correlated genes for GFM2:
Showing top 20/188 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GFM2 | RNF145 | 0.798335 | 3 | 0 | 3 |
| GFM2 | SUMF2 | 0.777471 | 3 | 0 | 3 |
| GFM2 | C5orf15 | 0.772337 | 3 | 0 | 3 |
| GFM2 | SRA1 | 0.760205 | 3 | 0 | 3 |
| GFM2 | UBLCP1 | 0.754024 | 4 | 0 | 4 |
| GFM2 | PSMD7 | 0.749843 | 3 | 0 | 3 |
| GFM2 | MRPS27 | 0.747168 | 4 | 0 | 4 |
| GFM2 | THG1L | 0.743706 | 3 | 0 | 3 |
| GFM2 | MITD1 | 0.740794 | 3 | 0 | 3 |
| GFM2 | C16orf87 | 0.737993 | 3 | 0 | 3 |
| GFM2 | ALDH7A1 | 0.73794 | 3 | 0 | 3 |
| GFM2 | MRPS18B | 0.73699 | 3 | 0 | 3 |
| GFM2 | PSEN1 | 0.736337 | 3 | 0 | 3 |
| GFM2 | PLEK2 | 0.732413 | 3 | 0 | 3 |
| GFM2 | ELP4 | 0.731875 | 3 | 0 | 3 |
| GFM2 | IMPDH2 | 0.730204 | 3 | 0 | 3 |
| GFM2 | CASP1 | 0.724764 | 3 | 0 | 3 |
| GFM2 | PNP | 0.722365 | 3 | 0 | 3 |
| GFM2 | SRFBP1 | 0.716907 | 3 | 0 | 3 |
| GFM2 | HSPB11 | 0.716738 | 3 | 0 | 3 |
For details and further investigation, click here
