| Full name: PLAG1 like zinc finger 1 | Alias Symbol: ZAC|LOT1 | ||
| Type: protein-coding gene | Cytoband: 6q24.2 | ||
| Entrez ID: 5325 | HGNC ID: HGNC:9046 | Ensembl Gene: ENSG00000118495 | OMIM ID: 603044 |
| Drug and gene relationship at DGIdb | |||
Expression of PLAGL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLAGL1 | 5325 | 209318_x_at | -1.0217 | 0.2909 | |
| GSE20347 | PLAGL1 | 5325 | 209318_x_at | -1.5811 | 0.0000 | |
| GSE23400 | PLAGL1 | 5325 | 209318_x_at | -1.4933 | 0.0000 | |
| GSE26886 | PLAGL1 | 5325 | 207002_s_at | -1.3121 | 0.0163 | |
| GSE29001 | PLAGL1 | 5325 | 207002_s_at | -2.3656 | 0.0005 | |
| GSE38129 | PLAGL1 | 5325 | 207002_s_at | -1.3507 | 0.0000 | |
| GSE45670 | PLAGL1 | 5325 | 207002_s_at | -1.0067 | 0.0027 | |
| GSE53622 | PLAGL1 | 5325 | 93234 | -1.2686 | 0.0000 | |
| GSE53624 | PLAGL1 | 5325 | 49478 | -1.1768 | 0.0000 | |
| GSE63941 | PLAGL1 | 5325 | 207943_x_at | -2.5985 | 0.0326 | |
| GSE77861 | PLAGL1 | 5325 | 207002_s_at | -1.5619 | 0.0133 | |
| GSE97050 | PLAGL1 | 5325 | A_24_P312041 | -0.4084 | 0.1726 | |
| SRP007169 | PLAGL1 | 5325 | RNAseq | -1.6603 | 0.0055 | |
| SRP008496 | PLAGL1 | 5325 | RNAseq | -1.8150 | 0.0000 | |
| SRP064894 | PLAGL1 | 5325 | RNAseq | -0.9393 | 0.0110 | |
| SRP133303 | PLAGL1 | 5325 | RNAseq | -0.7358 | 0.0423 | |
| SRP159526 | PLAGL1 | 5325 | RNAseq | -1.0576 | 0.0023 | |
| SRP193095 | PLAGL1 | 5325 | RNAseq | -1.2038 | 0.0000 | |
| SRP219564 | PLAGL1 | 5325 | RNAseq | -1.2559 | 0.0016 | |
| TCGA | PLAGL1 | 5325 | RNAseq | -0.3825 | 0.0022 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by PLAGL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLAGL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLAGL1 | 5325 | 2 | 4 | 24 | |
| GSE20123 | PLAGL1 | 5325 | 2 | 3 | 25 | |
| GSE43470 | PLAGL1 | 5325 | 5 | 0 | 38 | |
| GSE46452 | PLAGL1 | 5325 | 3 | 10 | 46 | |
| GSE47630 | PLAGL1 | 5325 | 9 | 4 | 27 | |
| GSE54993 | PLAGL1 | 5325 | 3 | 2 | 65 | |
| GSE54994 | PLAGL1 | 5325 | 8 | 8 | 37 | |
| GSE60625 | PLAGL1 | 5325 | 0 | 1 | 10 | |
| GSE74703 | PLAGL1 | 5325 | 4 | 0 | 32 | |
| GSE74704 | PLAGL1 | 5325 | 0 | 1 | 19 | |
| TCGA | PLAGL1 | 5325 | 12 | 19 | 65 |
Total number of gains: 48; Total number of losses: 52; Total Number of normals: 388.
Somatic mutations of PLAGL1:
Generating mutation plots.
Highly correlated genes for PLAGL1:
Showing top 20/885 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLAGL1 | HYMAI | 0.751033 | 9 | 0 | 9 |
| PLAGL1 | ZDHHC20 | 0.731552 | 3 | 0 | 3 |
| PLAGL1 | STK39 | 0.716988 | 10 | 0 | 10 |
| PLAGL1 | AIG1 | 0.716483 | 4 | 0 | 4 |
| PLAGL1 | SERPINB6 | 0.71164 | 10 | 0 | 9 |
| PLAGL1 | LMBRD1 | 0.709212 | 9 | 0 | 9 |
| PLAGL1 | KAT2B | 0.707894 | 10 | 0 | 9 |
| PLAGL1 | CGNL1 | 0.707566 | 5 | 0 | 5 |
| PLAGL1 | ECHDC2 | 0.707092 | 10 | 0 | 10 |
| PLAGL1 | SASH1 | 0.705841 | 10 | 0 | 9 |
| PLAGL1 | EPB41L3 | 0.70272 | 10 | 0 | 10 |
| PLAGL1 | BBIP1 | 0.699508 | 6 | 0 | 5 |
| PLAGL1 | SLC37A1 | 0.697061 | 9 | 0 | 9 |
| PLAGL1 | EPB41L4A | 0.696154 | 7 | 0 | 6 |
| PLAGL1 | ITSN2 | 0.688639 | 10 | 0 | 9 |
| PLAGL1 | HPGD | 0.686874 | 10 | 0 | 9 |
| PLAGL1 | CLCA4 | 0.684825 | 9 | 0 | 9 |
| PLAGL1 | RUFY3 | 0.684715 | 8 | 0 | 8 |
| PLAGL1 | KIAA0232 | 0.682519 | 11 | 0 | 10 |
| PLAGL1 | TCEAL8 | 0.68216 | 3 | 0 | 3 |
For details and further investigation, click here
