| Full name: NIPA like domain containing 2 | Alias Symbol: FLJ13955 | ||
| Type: protein-coding gene | Cytoband: 8q22.2 | ||
| Entrez ID: 79815 | HGNC ID: HGNC:25854 | Ensembl Gene: ENSG00000104361 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of NIPAL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NIPAL2 | 79815 | 227001_at | -0.6021 | 0.3752 | |
| GSE20347 | NIPAL2 | 79815 | 220128_s_at | -0.2803 | 0.0294 | |
| GSE23400 | NIPAL2 | 79815 | 220128_s_at | -0.2723 | 0.0000 | |
| GSE26886 | NIPAL2 | 79815 | 227001_at | -1.4075 | 0.0002 | |
| GSE29001 | NIPAL2 | 79815 | 220128_s_at | -0.3563 | 0.0581 | |
| GSE38129 | NIPAL2 | 79815 | 220128_s_at | -0.2733 | 0.0584 | |
| GSE45670 | NIPAL2 | 79815 | 227001_at | -0.6873 | 0.0108 | |
| GSE53622 | NIPAL2 | 79815 | 7372 | -1.2597 | 0.0000 | |
| GSE53624 | NIPAL2 | 79815 | 7372 | -1.3146 | 0.0000 | |
| GSE63941 | NIPAL2 | 79815 | 227001_at | -2.1048 | 0.1220 | |
| GSE77861 | NIPAL2 | 79815 | 227001_at | -1.1753 | 0.0042 | |
| GSE97050 | NIPAL2 | 79815 | A_23_P146111 | -0.3663 | 0.2628 | |
| SRP007169 | NIPAL2 | 79815 | RNAseq | -2.0375 | 0.0005 | |
| SRP008496 | NIPAL2 | 79815 | RNAseq | -1.8395 | 0.0000 | |
| SRP064894 | NIPAL2 | 79815 | RNAseq | -0.6490 | 0.0157 | |
| SRP133303 | NIPAL2 | 79815 | RNAseq | -1.1906 | 0.0000 | |
| SRP159526 | NIPAL2 | 79815 | RNAseq | -1.7184 | 0.0017 | |
| SRP193095 | NIPAL2 | 79815 | RNAseq | -1.1247 | 0.0000 | |
| SRP219564 | NIPAL2 | 79815 | RNAseq | -1.0502 | 0.0998 | |
| TCGA | NIPAL2 | 79815 | RNAseq | -0.1718 | 0.1215 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by NIPAL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NIPAL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NIPAL2 | 79815 | 16 | 0 | 14 | |
| GSE20123 | NIPAL2 | 79815 | 17 | 0 | 13 | |
| GSE43470 | NIPAL2 | 79815 | 21 | 1 | 21 | |
| GSE46452 | NIPAL2 | 79815 | 23 | 0 | 36 | |
| GSE47630 | NIPAL2 | 79815 | 24 | 0 | 16 | |
| GSE54993 | NIPAL2 | 79815 | 0 | 20 | 50 | |
| GSE54994 | NIPAL2 | 79815 | 37 | 1 | 15 | |
| GSE60625 | NIPAL2 | 79815 | 0 | 4 | 7 | |
| GSE74703 | NIPAL2 | 79815 | 18 | 1 | 17 | |
| GSE74704 | NIPAL2 | 79815 | 12 | 0 | 8 | |
| TCGA | NIPAL2 | 79815 | 56 | 1 | 39 |
Total number of gains: 224; Total number of losses: 28; Total Number of normals: 236.
Somatic mutations of NIPAL2:
Generating mutation plots.
Highly correlated genes for NIPAL2:
Showing top 20/1182 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NIPAL2 | NCCRP1 | 0.756934 | 3 | 0 | 3 |
| NIPAL2 | STXBP5 | 0.756146 | 6 | 0 | 6 |
| NIPAL2 | TMPRSS11A | 0.746339 | 3 | 0 | 3 |
| NIPAL2 | PGLYRP3 | 0.740201 | 3 | 0 | 3 |
| NIPAL2 | CXCL17 | 0.738366 | 7 | 0 | 7 |
| NIPAL2 | ZDHHC20 | 0.730239 | 4 | 0 | 4 |
| NIPAL2 | FAM219B | 0.729114 | 3 | 0 | 3 |
| NIPAL2 | UPK3B | 0.721524 | 3 | 0 | 3 |
| NIPAL2 | FAM3D | 0.717833 | 7 | 0 | 7 |
| NIPAL2 | CAPN14 | 0.716636 | 6 | 0 | 6 |
| NIPAL2 | C6orf132 | 0.71544 | 7 | 0 | 7 |
| NIPAL2 | EPB41L4A | 0.715001 | 9 | 0 | 8 |
| NIPAL2 | ELF3 | 0.709431 | 9 | 0 | 9 |
| NIPAL2 | SPRR2F | 0.706185 | 3 | 0 | 3 |
| NIPAL2 | OTOP3 | 0.705611 | 3 | 0 | 3 |
| NIPAL2 | KRT78 | 0.703589 | 7 | 0 | 7 |
| NIPAL2 | SPAG17 | 0.703562 | 5 | 0 | 5 |
| NIPAL2 | EPS8L2 | 0.70134 | 11 | 0 | 11 |
| NIPAL2 | ST6GALNAC1 | 0.700887 | 7 | 0 | 6 |
| NIPAL2 | C15orf48 | 0.700701 | 6 | 0 | 6 |
For details and further investigation, click here
