| Full name: major facilitator superfamily domain containing 1 | Alias Symbol: FLJ14153|UG0581B09 | ||
| Type: protein-coding gene | Cytoband: 3q25.32 | ||
| Entrez ID: 64747 | HGNC ID: HGNC:25874 | Ensembl Gene: ENSG00000118855 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MFSD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MFSD1 | 64747 | 218109_s_at | -0.2879 | 0.6337 | |
| GSE20347 | MFSD1 | 64747 | 218109_s_at | -1.0210 | 0.0000 | |
| GSE23400 | MFSD1 | 64747 | 218109_s_at | -0.5184 | 0.0000 | |
| GSE26886 | MFSD1 | 64747 | 218109_s_at | -1.5278 | 0.0000 | |
| GSE29001 | MFSD1 | 64747 | 218109_s_at | -0.7381 | 0.0123 | |
| GSE38129 | MFSD1 | 64747 | 218109_s_at | -0.5466 | 0.0077 | |
| GSE45670 | MFSD1 | 64747 | 218109_s_at | -0.5405 | 0.0029 | |
| GSE53622 | MFSD1 | 64747 | 99522 | -0.6523 | 0.0000 | |
| GSE53624 | MFSD1 | 64747 | 99522 | -0.7330 | 0.0000 | |
| GSE63941 | MFSD1 | 64747 | 218109_s_at | -1.9541 | 0.0014 | |
| GSE77861 | MFSD1 | 64747 | 218109_s_at | -1.3265 | 0.0031 | |
| GSE97050 | MFSD1 | 64747 | A_33_P3251985 | 0.2252 | 0.6165 | |
| SRP007169 | MFSD1 | 64747 | RNAseq | -2.0107 | 0.0000 | |
| SRP008496 | MFSD1 | 64747 | RNAseq | -1.5626 | 0.0000 | |
| SRP064894 | MFSD1 | 64747 | RNAseq | -0.4013 | 0.0326 | |
| SRP133303 | MFSD1 | 64747 | RNAseq | -0.3155 | 0.1263 | |
| SRP159526 | MFSD1 | 64747 | RNAseq | -0.2304 | 0.5875 | |
| SRP193095 | MFSD1 | 64747 | RNAseq | -0.8112 | 0.0000 | |
| SRP219564 | MFSD1 | 64747 | RNAseq | -0.2572 | 0.5939 | |
| TCGA | MFSD1 | 64747 | RNAseq | 0.0420 | 0.4257 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by MFSD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MFSD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MFSD1 | 64747 | 22 | 0 | 8 | |
| GSE20123 | MFSD1 | 64747 | 22 | 0 | 8 | |
| GSE43470 | MFSD1 | 64747 | 23 | 0 | 20 | |
| GSE46452 | MFSD1 | 64747 | 18 | 2 | 39 | |
| GSE47630 | MFSD1 | 64747 | 18 | 4 | 18 | |
| GSE54993 | MFSD1 | 64747 | 1 | 11 | 58 | |
| GSE54994 | MFSD1 | 64747 | 38 | 1 | 14 | |
| GSE60625 | MFSD1 | 64747 | 0 | 6 | 5 | |
| GSE74703 | MFSD1 | 64747 | 20 | 0 | 16 | |
| GSE74704 | MFSD1 | 64747 | 14 | 0 | 6 | |
| TCGA | MFSD1 | 64747 | 75 | 1 | 20 |
Total number of gains: 251; Total number of losses: 25; Total Number of normals: 212.
Somatic mutations of MFSD1:
Generating mutation plots.
Highly correlated genes for MFSD1:
Showing top 20/539 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MFSD1 | SFTA2 | 0.775372 | 4 | 0 | 4 |
| MFSD1 | ATP13A4 | 0.773944 | 6 | 0 | 6 |
| MFSD1 | ETFDH | 0.770558 | 9 | 0 | 9 |
| MFSD1 | S100A16 | 0.768821 | 6 | 0 | 6 |
| MFSD1 | FAM3D | 0.763906 | 6 | 0 | 6 |
| MFSD1 | GGT6 | 0.757251 | 7 | 0 | 7 |
| MFSD1 | BNIPL | 0.755303 | 6 | 0 | 6 |
| MFSD1 | RAB11FIP4 | 0.753753 | 4 | 0 | 4 |
| MFSD1 | SMAGP | 0.752619 | 11 | 0 | 10 |
| MFSD1 | SH2D1B | 0.752593 | 4 | 0 | 3 |
| MFSD1 | TP53I3 | 0.752447 | 11 | 0 | 11 |
| MFSD1 | RAET1E | 0.751425 | 7 | 0 | 7 |
| MFSD1 | MMEL1 | 0.748931 | 4 | 0 | 4 |
| MFSD1 | KRT78 | 0.748161 | 6 | 0 | 5 |
| MFSD1 | ZDHHC20 | 0.746866 | 5 | 0 | 5 |
| MFSD1 | DENND2D | 0.74022 | 10 | 0 | 9 |
| MFSD1 | CCDC62 | 0.740084 | 3 | 0 | 3 |
| MFSD1 | TTC39A | 0.739539 | 10 | 0 | 9 |
| MFSD1 | CLIC3 | 0.737886 | 8 | 0 | 8 |
| MFSD1 | SNORA68 | 0.737521 | 4 | 0 | 3 |
For details and further investigation, click here
