ZFAND5

 

Full name: zinc finger AN1-type containing 5 Alias Symbol: ZFAND5A
Type: protein-coding gene Cytoband: 9q21.13
Entrez ID: 7763 HGNC ID: HGNC:13008 Ensembl Gene: ENSG00000107372 OMIM ID: 604761
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ZFAND5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZFAND5 7763 210275_s_at -0.4949 0.3283
GSE20347 ZFAND5 7763 210275_s_at 0.0420 0.7470
GSE23400 ZFAND5 7763 210275_s_at -0.3337 0.0000
GSE26886 ZFAND5 7763 210275_s_at -1.0821 0.0000
GSE29001 ZFAND5 7763 210275_s_at -0.3287 0.1592
GSE38129 ZFAND5 7763 210275_s_at -0.1040 0.3971
GSE45670 ZFAND5 7763 210275_s_at -0.3622 0.0148
GSE53622 ZFAND5 7763 50544 -0.5499 0.0000
GSE53624 ZFAND5 7763 112572 -0.5237 0.0000
GSE63941 ZFAND5 7763 210275_s_at -1.4075 0.0058
GSE77861 ZFAND5 7763 210275_s_at 0.0205 0.9550
GSE97050 ZFAND5 7763 A_24_P278172 -0.5063 0.1049
SRP007169 ZFAND5 7763 RNAseq -1.4490 0.0002
SRP008496 ZFAND5 7763 RNAseq -1.3991 0.0000
SRP064894 ZFAND5 7763 RNAseq -1.0014 0.0000
SRP133303 ZFAND5 7763 RNAseq -0.4424 0.0291
SRP159526 ZFAND5 7763 RNAseq -0.6903 0.0376
SRP193095 ZFAND5 7763 RNAseq -0.8703 0.0000
SRP219564 ZFAND5 7763 RNAseq -0.3154 0.5013
TCGA ZFAND5 7763 RNAseq -0.1609 0.0002

Upregulated datasets: 0; Downregulated datasets: 5.  


 

Survival by ZFAND5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZFAND5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZFAND5 7763 6 10 14
GSE20123 ZFAND5 7763 6 10 14
GSE43470 ZFAND5 7763 6 5 32
GSE46452 ZFAND5 7763 6 14 39
GSE47630 ZFAND5 7763 1 18 21
GSE54993 ZFAND5 7763 4 1 65
GSE54994 ZFAND5 7763 4 13 36
GSE60625 ZFAND5 7763 0 0 11
GSE74703 ZFAND5 7763 5 4 27
GSE74704 ZFAND5 7763 3 8 9
TCGA ZFAND5 7763 19 27 50

Total number of gains: 60; Total number of losses: 110; Total Number of normals: 318.  


 

Somatic mutations of ZFAND5:

 

Generating mutation plots.

 

Highly correlated genes for ZFAND5:

 

Showing top 20/856 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZFAND5DDR20.812928303
ZFAND5FIBIN0.80637303
ZFAND5FAM160B10.805061303
ZFAND5RGMB0.800384303
ZFAND5CNRIP10.797205303
ZFAND5FNIP20.78893303
ZFAND5TMEM50B0.785419303
ZFAND5TMEM170B0.784953303
ZFAND5TBC1D200.772563303
ZFAND5ARMCX20.771626303
ZFAND5ANGPT10.764193303
ZFAND5LSM14A0.762747303
ZFAND5LRCH20.761549303
ZFAND5ZNF3470.74101303
ZFAND5SENP80.740906303
ZFAND5KCTD120.738111303
ZFAND5ARHGAP170.734426303
ZFAND5HDHD20.732342403
ZFAND5EPC10.724587403
ZFAND5NLGN4Y0.722057303

For details and further investigation, click here