| Full name: zinc finger FYVE-type containing 19 | Alias Symbol: FLJ14840|ANCHR | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 84936 | HGNC ID: HGNC:20758 | Ensembl Gene: ENSG00000166140 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZFYVE19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZFYVE19 | 84936 | 225843_at | -0.0205 | 0.9593 | |
| GSE26886 | ZFYVE19 | 84936 | 225843_at | -0.1828 | 0.3919 | |
| GSE45670 | ZFYVE19 | 84936 | 225843_at | -0.2975 | 0.0842 | |
| GSE53622 | ZFYVE19 | 84936 | 31823 | -0.4729 | 0.0000 | |
| GSE53624 | ZFYVE19 | 84936 | 31823 | -0.4075 | 0.0000 | |
| GSE63941 | ZFYVE19 | 84936 | 225843_at | 0.5524 | 0.2066 | |
| GSE77861 | ZFYVE19 | 84936 | 225843_at | 0.0321 | 0.8208 | |
| GSE97050 | ZFYVE19 | 84936 | A_23_P65930 | -0.1405 | 0.5463 | |
| SRP007169 | ZFYVE19 | 84936 | RNAseq | -1.9102 | 0.0001 | |
| SRP008496 | ZFYVE19 | 84936 | RNAseq | -1.7561 | 0.0000 | |
| SRP064894 | ZFYVE19 | 84936 | RNAseq | -0.1995 | 0.4510 | |
| SRP133303 | ZFYVE19 | 84936 | RNAseq | -0.3123 | 0.0555 | |
| SRP159526 | ZFYVE19 | 84936 | RNAseq | -0.3918 | 0.0624 | |
| SRP193095 | ZFYVE19 | 84936 | RNAseq | -0.2826 | 0.0016 | |
| SRP219564 | ZFYVE19 | 84936 | RNAseq | -0.6235 | 0.1373 | |
| TCGA | ZFYVE19 | 84936 | RNAseq | 0.0233 | 0.6907 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ZFYVE19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZFYVE19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZFYVE19 | 84936 | 3 | 6 | 21 | |
| GSE20123 | ZFYVE19 | 84936 | 3 | 6 | 21 | |
| GSE43470 | ZFYVE19 | 84936 | 4 | 6 | 33 | |
| GSE46452 | ZFYVE19 | 84936 | 3 | 7 | 49 | |
| GSE47630 | ZFYVE19 | 84936 | 8 | 11 | 21 | |
| GSE54993 | ZFYVE19 | 84936 | 4 | 6 | 60 | |
| GSE54994 | ZFYVE19 | 84936 | 5 | 7 | 41 | |
| GSE60625 | ZFYVE19 | 84936 | 4 | 0 | 7 | |
| GSE74703 | ZFYVE19 | 84936 | 4 | 5 | 27 | |
| GSE74704 | ZFYVE19 | 84936 | 2 | 4 | 14 | |
| TCGA | ZFYVE19 | 84936 | 11 | 18 | 67 |
Total number of gains: 51; Total number of losses: 76; Total Number of normals: 361.
Somatic mutations of ZFYVE19:
Generating mutation plots.
Highly correlated genes for ZFYVE19:
Showing top 20/64 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZFYVE19 | CUL9 | 0.703271 | 3 | 0 | 3 |
| ZFYVE19 | NXF3 | 0.684193 | 3 | 0 | 3 |
| ZFYVE19 | MUC22 | 0.657125 | 3 | 0 | 3 |
| ZFYVE19 | SPTBN5 | 0.649882 | 5 | 0 | 3 |
| ZFYVE19 | SLC35C1 | 0.634349 | 4 | 0 | 3 |
| ZFYVE19 | PRSS27 | 0.631068 | 3 | 0 | 3 |
| ZFYVE19 | MAFG | 0.62262 | 4 | 0 | 3 |
| ZFYVE19 | PFN4 | 0.61991 | 3 | 0 | 3 |
| ZFYVE19 | ACCS | 0.612006 | 3 | 0 | 3 |
| ZFYVE19 | ENTPD5 | 0.6095 | 5 | 0 | 3 |
| ZFYVE19 | TJP2 | 0.609357 | 5 | 0 | 3 |
| ZFYVE19 | ZNF692 | 0.598442 | 4 | 0 | 3 |
| ZFYVE19 | EPN2 | 0.589278 | 3 | 0 | 3 |
| ZFYVE19 | ESAM | 0.580803 | 4 | 0 | 3 |
| ZFYVE19 | NCCRP1 | 0.578895 | 3 | 0 | 3 |
| ZFYVE19 | DNAJC17 | 0.577844 | 8 | 0 | 5 |
| ZFYVE19 | LGALS3 | 0.576727 | 4 | 0 | 3 |
| ZFYVE19 | ATP6V0A4 | 0.572896 | 5 | 0 | 4 |
| ZFYVE19 | CIDEA | 0.57169 | 5 | 0 | 3 |
| ZFYVE19 | PTK6 | 0.570772 | 5 | 0 | 3 |
For details and further investigation, click here
