| Full name: zinc finger matrin-type 5 | Alias Symbol: SNRNP20 | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 55954 | HGNC ID: HGNC:28046 | Ensembl Gene: ENSG00000100319 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZMAT5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZMAT5 | 55954 | 218752_at | -0.3452 | 0.4924 | |
| GSE20347 | ZMAT5 | 55954 | 218752_at | -0.4883 | 0.0000 | |
| GSE23400 | ZMAT5 | 55954 | 218752_at | -0.1949 | 0.0001 | |
| GSE26886 | ZMAT5 | 55954 | 218752_at | -0.0038 | 0.9858 | |
| GSE29001 | ZMAT5 | 55954 | 218752_at | -0.3272 | 0.1483 | |
| GSE38129 | ZMAT5 | 55954 | 218752_at | -0.4877 | 0.0001 | |
| GSE45670 | ZMAT5 | 55954 | 218752_at | 0.1257 | 0.4953 | |
| GSE53622 | ZMAT5 | 55954 | 57847 | -0.1157 | 0.3242 | |
| GSE53624 | ZMAT5 | 55954 | 57847 | -0.2205 | 0.0449 | |
| GSE63941 | ZMAT5 | 55954 | 218752_at | 0.6903 | 0.0562 | |
| GSE77861 | ZMAT5 | 55954 | 218752_at | -0.3515 | 0.1334 | |
| GSE97050 | ZMAT5 | 55954 | A_23_P132248 | 0.2089 | 0.5399 | |
| SRP007169 | ZMAT5 | 55954 | RNAseq | -1.2800 | 0.0136 | |
| SRP008496 | ZMAT5 | 55954 | RNAseq | -0.9049 | 0.0125 | |
| SRP064894 | ZMAT5 | 55954 | RNAseq | 0.1127 | 0.7332 | |
| SRP133303 | ZMAT5 | 55954 | RNAseq | -0.1515 | 0.3938 | |
| SRP159526 | ZMAT5 | 55954 | RNAseq | -0.4605 | 0.0478 | |
| SRP193095 | ZMAT5 | 55954 | RNAseq | -0.4364 | 0.0047 | |
| SRP219564 | ZMAT5 | 55954 | RNAseq | -0.3869 | 0.3603 | |
| TCGA | ZMAT5 | 55954 | RNAseq | -0.0896 | 0.3264 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZMAT5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZMAT5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZMAT5 | 55954 | 3 | 5 | 22 | |
| GSE20123 | ZMAT5 | 55954 | 3 | 4 | 23 | |
| GSE43470 | ZMAT5 | 55954 | 4 | 5 | 34 | |
| GSE46452 | ZMAT5 | 55954 | 31 | 1 | 27 | |
| GSE47630 | ZMAT5 | 55954 | 8 | 5 | 27 | |
| GSE54993 | ZMAT5 | 55954 | 3 | 6 | 61 | |
| GSE54994 | ZMAT5 | 55954 | 11 | 8 | 34 | |
| GSE60625 | ZMAT5 | 55954 | 5 | 0 | 6 | |
| GSE74703 | ZMAT5 | 55954 | 4 | 4 | 28 | |
| GSE74704 | ZMAT5 | 55954 | 0 | 1 | 19 | |
| TCGA | ZMAT5 | 55954 | 27 | 15 | 54 |
Total number of gains: 99; Total number of losses: 54; Total Number of normals: 335.
Somatic mutations of ZMAT5:
Generating mutation plots.
Highly correlated genes for ZMAT5:
Showing top 20/375 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZMAT5 | SNX15 | 0.673721 | 3 | 0 | 3 |
| ZMAT5 | USP19 | 0.664596 | 3 | 0 | 3 |
| ZMAT5 | MRPL49 | 0.66208 | 3 | 0 | 3 |
| ZMAT5 | ZSWIM5 | 0.658709 | 3 | 0 | 3 |
| ZMAT5 | WDR61 | 0.648044 | 4 | 0 | 3 |
| ZMAT5 | LRRC28 | 0.647002 | 4 | 0 | 4 |
| ZMAT5 | MLST8 | 0.646839 | 3 | 0 | 3 |
| ZMAT5 | THG1L | 0.639861 | 3 | 0 | 3 |
| ZMAT5 | PSMD9 | 0.63797 | 4 | 0 | 3 |
| ZMAT5 | DNAH1 | 0.637064 | 4 | 0 | 3 |
| ZMAT5 | RGS14 | 0.632663 | 4 | 0 | 4 |
| ZMAT5 | GPS2 | 0.632638 | 4 | 0 | 4 |
| ZMAT5 | ZNF214 | 0.63259 | 4 | 0 | 3 |
| ZMAT5 | SLC24A1 | 0.630375 | 3 | 0 | 3 |
| ZMAT5 | ATP6V1E1 | 0.6283 | 8 | 0 | 6 |
| ZMAT5 | UBE2J2 | 0.623152 | 3 | 0 | 3 |
| ZMAT5 | GMPPB | 0.622988 | 3 | 0 | 3 |
| ZMAT5 | NPTXR | 0.619945 | 5 | 0 | 5 |
| ZMAT5 | AGFG2 | 0.619833 | 6 | 0 | 4 |
| ZMAT5 | ANXA11 | 0.619234 | 6 | 0 | 5 |
For details and further investigation, click here
