| Full name: zinc finger protein 22 | Alias Symbol: KOX15|HKR-T1|ZNF422|Zfp422 | ||
| Type: protein-coding gene | Cytoband: 10q11.21 | ||
| Entrez ID: 7570 | HGNC ID: HGNC:13012 | Ensembl Gene: ENSG00000165512 | OMIM ID: 194529 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF22:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF22 | 7570 | 218005_at | 0.3238 | 0.3839 | |
| GSE20347 | ZNF22 | 7570 | 218005_at | 0.7891 | 0.0060 | |
| GSE23400 | ZNF22 | 7570 | 218005_at | 0.5830 | 0.0000 | |
| GSE26886 | ZNF22 | 7570 | 218005_at | 1.0708 | 0.0271 | |
| GSE29001 | ZNF22 | 7570 | 218005_at | 0.6290 | 0.0441 | |
| GSE38129 | ZNF22 | 7570 | 218005_at | 0.6134 | 0.0092 | |
| GSE45670 | ZNF22 | 7570 | 218005_at | -0.3031 | 0.2185 | |
| GSE53622 | ZNF22 | 7570 | 45539 | 0.4347 | 0.0001 | |
| GSE53624 | ZNF22 | 7570 | 45539 | 0.6707 | 0.0000 | |
| GSE63941 | ZNF22 | 7570 | 218005_at | -0.8821 | 0.6470 | |
| GSE77861 | ZNF22 | 7570 | 218005_at | 0.1713 | 0.8159 | |
| GSE97050 | ZNF22 | 7570 | A_23_P202458 | 0.2942 | 0.2308 | |
| SRP007169 | ZNF22 | 7570 | RNAseq | 0.4779 | 0.3735 | |
| SRP008496 | ZNF22 | 7570 | RNAseq | 0.6881 | 0.0649 | |
| SRP064894 | ZNF22 | 7570 | RNAseq | 0.3611 | 0.0713 | |
| SRP133303 | ZNF22 | 7570 | RNAseq | 0.5204 | 0.0155 | |
| SRP159526 | ZNF22 | 7570 | RNAseq | 0.3537 | 0.1351 | |
| SRP193095 | ZNF22 | 7570 | RNAseq | 0.4924 | 0.0027 | |
| SRP219564 | ZNF22 | 7570 | RNAseq | 0.5097 | 0.0942 | |
| TCGA | ZNF22 | 7570 | RNAseq | 0.0027 | 0.9682 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZNF22 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF22:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF22 | 7570 | 3 | 5 | 22 | |
| GSE20123 | ZNF22 | 7570 | 3 | 5 | 22 | |
| GSE43470 | ZNF22 | 7570 | 1 | 6 | 36 | |
| GSE46452 | ZNF22 | 7570 | 0 | 13 | 46 | |
| GSE47630 | ZNF22 | 7570 | 4 | 12 | 24 | |
| GSE54993 | ZNF22 | 7570 | 9 | 0 | 61 | |
| GSE54994 | ZNF22 | 7570 | 2 | 10 | 41 | |
| GSE60625 | ZNF22 | 7570 | 0 | 0 | 11 | |
| GSE74703 | ZNF22 | 7570 | 1 | 3 | 32 | |
| GSE74704 | ZNF22 | 7570 | 2 | 4 | 14 | |
| TCGA | ZNF22 | 7570 | 17 | 17 | 62 |
Total number of gains: 42; Total number of losses: 75; Total Number of normals: 371.
Somatic mutations of ZNF22:
Generating mutation plots.
Highly correlated genes for ZNF22:
Showing top 20/1104 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF22 | RIMKLB | 0.800957 | 3 | 0 | 3 |
| ZNF22 | ZNF468 | 0.753593 | 3 | 0 | 3 |
| ZNF22 | PGM2L1 | 0.744439 | 3 | 0 | 3 |
| ZNF22 | IFT46 | 0.742124 | 3 | 0 | 3 |
| ZNF22 | PPP6R1 | 0.739972 | 3 | 0 | 3 |
| ZNF22 | RNASEH2B | 0.739717 | 4 | 0 | 4 |
| ZNF22 | BIRC5 | 0.701705 | 3 | 0 | 3 |
| ZNF22 | HYLS1 | 0.701259 | 4 | 0 | 3 |
| ZNF22 | DYRK2 | 0.700454 | 3 | 0 | 3 |
| ZNF22 | SEC22C | 0.699499 | 4 | 0 | 3 |
| ZNF22 | FCGR3A | 0.696554 | 3 | 0 | 3 |
| ZNF22 | STARD3NL | 0.694446 | 6 | 0 | 5 |
| ZNF22 | CCDC14 | 0.693517 | 4 | 0 | 3 |
| ZNF22 | GHR | 0.692147 | 3 | 0 | 3 |
| ZNF22 | SLC35B2 | 0.688668 | 3 | 0 | 3 |
| ZNF22 | SSR3 | 0.687365 | 5 | 0 | 4 |
| ZNF22 | TBL2 | 0.686134 | 4 | 0 | 3 |
| ZNF22 | SLC35B3 | 0.683613 | 4 | 0 | 3 |
| ZNF22 | CNNM3 | 0.683252 | 4 | 0 | 4 |
| ZNF22 | SESN3 | 0.681633 | 3 | 0 | 3 |
For details and further investigation, click here
