| Full name: LRR binding FLII interacting protein 1 | Alias Symbol: FLAP-1|FLIIAP1|TRIP|GCF-2|HUFI-1 | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 9208 | HGNC ID: HGNC:6702 | Ensembl Gene: ENSG00000124831 | OMIM ID: 603256 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRFIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRFIP1 | 9208 | 211452_x_at | -0.1104 | 0.9251 | |
| GSE20347 | LRRFIP1 | 9208 | 211452_x_at | -0.0061 | 0.9740 | |
| GSE23400 | LRRFIP1 | 9208 | 211452_x_at | -0.1878 | 0.0141 | |
| GSE26886 | LRRFIP1 | 9208 | 211452_x_at | -0.3054 | 0.0878 | |
| GSE29001 | LRRFIP1 | 9208 | 211452_x_at | -0.1124 | 0.5516 | |
| GSE38129 | LRRFIP1 | 9208 | 211452_x_at | -0.2283 | 0.2354 | |
| GSE45670 | LRRFIP1 | 9208 | 211452_x_at | 0.0343 | 0.7972 | |
| GSE53622 | LRRFIP1 | 9208 | 94376 | -0.3704 | 0.0000 | |
| GSE53624 | LRRFIP1 | 9208 | 41905 | -0.8768 | 0.0000 | |
| GSE63941 | LRRFIP1 | 9208 | 227391_x_at | 0.4670 | 0.2006 | |
| GSE77861 | LRRFIP1 | 9208 | 211452_x_at | 0.2853 | 0.3408 | |
| GSE97050 | LRRFIP1 | 9208 | A_33_P3374085 | -0.3379 | 0.2416 | |
| SRP007169 | LRRFIP1 | 9208 | RNAseq | -0.9085 | 0.0123 | |
| SRP008496 | LRRFIP1 | 9208 | RNAseq | -0.8500 | 0.0000 | |
| SRP064894 | LRRFIP1 | 9208 | RNAseq | -0.6506 | 0.0007 | |
| SRP133303 | LRRFIP1 | 9208 | RNAseq | -0.2027 | 0.1831 | |
| SRP159526 | LRRFIP1 | 9208 | RNAseq | -0.9546 | 0.0019 | |
| SRP193095 | LRRFIP1 | 9208 | RNAseq | -0.4042 | 0.0032 | |
| SRP219564 | LRRFIP1 | 9208 | RNAseq | -0.5711 | 0.0930 | |
| TCGA | LRRFIP1 | 9208 | RNAseq | -0.1135 | 0.0361 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRRFIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRFIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRFIP1 | 9208 | 1 | 12 | 17 | |
| GSE20123 | LRRFIP1 | 9208 | 1 | 12 | 17 | |
| GSE43470 | LRRFIP1 | 9208 | 1 | 9 | 33 | |
| GSE46452 | LRRFIP1 | 9208 | 0 | 5 | 54 | |
| GSE47630 | LRRFIP1 | 9208 | 4 | 5 | 31 | |
| GSE54993 | LRRFIP1 | 9208 | 3 | 2 | 65 | |
| GSE54994 | LRRFIP1 | 9208 | 8 | 10 | 35 | |
| GSE60625 | LRRFIP1 | 9208 | 0 | 3 | 8 | |
| GSE74703 | LRRFIP1 | 9208 | 1 | 7 | 28 | |
| GSE74704 | LRRFIP1 | 9208 | 1 | 5 | 14 | |
| TCGA | LRRFIP1 | 9208 | 12 | 27 | 57 |
Total number of gains: 32; Total number of losses: 97; Total Number of normals: 359.
Somatic mutations of LRRFIP1:
Generating mutation plots.
Highly correlated genes for LRRFIP1:
Showing top 20/229 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRFIP1 | SLC35E1 | 0.732748 | 9 | 0 | 8 |
| LRRFIP1 | DBT | 0.703352 | 9 | 0 | 9 |
| LRRFIP1 | PPP2R3A | 0.69972 | 3 | 0 | 3 |
| LRRFIP1 | UBQLN4 | 0.697629 | 6 | 0 | 6 |
| LRRFIP1 | DIP2A | 0.688557 | 11 | 0 | 11 |
| LRRFIP1 | UCP3 | 0.688158 | 4 | 0 | 4 |
| LRRFIP1 | ZNF577 | 0.683835 | 3 | 0 | 3 |
| LRRFIP1 | METRNL | 0.683532 | 3 | 0 | 3 |
| LRRFIP1 | HAUS2 | 0.67445 | 10 | 0 | 7 |
| LRRFIP1 | ZC3H7B | 0.66759 | 7 | 0 | 6 |
| LRRFIP1 | KLHL28 | 0.661036 | 7 | 0 | 5 |
| LRRFIP1 | CCDC9 | 0.659434 | 3 | 0 | 3 |
| LRRFIP1 | ADH4 | 0.657268 | 4 | 0 | 4 |
| LRRFIP1 | ZNF431 | 0.642395 | 4 | 0 | 4 |
| LRRFIP1 | MAGI1 | 0.639217 | 6 | 0 | 5 |
| LRRFIP1 | SH3BGRL2 | 0.634391 | 3 | 0 | 3 |
| LRRFIP1 | IVL | 0.633946 | 3 | 0 | 3 |
| LRRFIP1 | KCTD3 | 0.633418 | 4 | 0 | 3 |
| LRRFIP1 | ANKRD35 | 0.632711 | 4 | 0 | 4 |
| LRRFIP1 | MAFF | 0.631199 | 5 | 0 | 3 |
For details and further investigation, click here
