| Full name: CGRP receptor component | Alias Symbol: CGRP-RCP|RCP|RCP9 | ||
| Type: protein-coding gene | Cytoband: 7q11.21 | ||
| Entrez ID: 27297 | HGNC ID: HGNC:17888 | Ensembl Gene: ENSG00000241258 | OMIM ID: 606121 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CRCP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRCP | 27297 | 203898_at | 0.4476 | 0.3296 | |
| GSE20347 | CRCP | 27297 | 203898_at | 0.3003 | 0.0353 | |
| GSE23400 | CRCP | 27297 | 203899_s_at | -0.0851 | 0.0489 | |
| GSE26886 | CRCP | 27297 | 203899_s_at | 0.2606 | 0.1269 | |
| GSE29001 | CRCP | 27297 | 203898_at | 0.2577 | 0.1750 | |
| GSE38129 | CRCP | 27297 | 203898_at | 0.3305 | 0.0034 | |
| GSE45670 | CRCP | 27297 | 203898_at | 0.0927 | 0.4973 | |
| GSE53622 | CRCP | 27297 | 46397 | 0.3399 | 0.0000 | |
| GSE53624 | CRCP | 27297 | 94809 | 0.4106 | 0.0000 | |
| GSE63941 | CRCP | 27297 | 203898_at | -0.2502 | 0.4878 | |
| GSE77861 | CRCP | 27297 | 203899_s_at | 0.0791 | 0.5865 | |
| GSE97050 | CRCP | 27297 | A_24_P916656 | 0.3548 | 0.3442 | |
| SRP007169 | CRCP | 27297 | RNAseq | -0.1568 | 0.6593 | |
| SRP008496 | CRCP | 27297 | RNAseq | 0.1319 | 0.5257 | |
| SRP064894 | CRCP | 27297 | RNAseq | 0.2075 | 0.0670 | |
| SRP133303 | CRCP | 27297 | RNAseq | 0.1675 | 0.0551 | |
| SRP159526 | CRCP | 27297 | RNAseq | 0.1138 | 0.6144 | |
| SRP193095 | CRCP | 27297 | RNAseq | 0.1764 | 0.1225 | |
| SRP219564 | CRCP | 27297 | RNAseq | -0.0049 | 0.9862 | |
| TCGA | CRCP | 27297 | RNAseq | -0.0498 | 0.3602 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CRCP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRCP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRCP | 27297 | 11 | 2 | 17 | |
| GSE20123 | CRCP | 27297 | 10 | 2 | 18 | |
| GSE43470 | CRCP | 27297 | 2 | 1 | 40 | |
| GSE46452 | CRCP | 27297 | 13 | 0 | 46 | |
| GSE47630 | CRCP | 27297 | 7 | 1 | 32 | |
| GSE54993 | CRCP | 27297 | 2 | 7 | 61 | |
| GSE54994 | CRCP | 27297 | 12 | 4 | 37 | |
| GSE60625 | CRCP | 27297 | 0 | 0 | 11 | |
| GSE74703 | CRCP | 27297 | 2 | 1 | 33 | |
| GSE74704 | CRCP | 27297 | 5 | 1 | 14 | |
| TCGA | CRCP | 27297 | 45 | 7 | 44 |
Total number of gains: 109; Total number of losses: 26; Total Number of normals: 353.
Somatic mutations of CRCP:
Generating mutation plots.
Highly correlated genes for CRCP:
Showing top 20/310 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRCP | VPS41 | 0.779565 | 3 | 0 | 3 |
| CRCP | GRWD1 | 0.765149 | 3 | 0 | 3 |
| CRCP | MZT1 | 0.763134 | 3 | 0 | 3 |
| CRCP | ZNF577 | 0.759684 | 3 | 0 | 3 |
| CRCP | RRP9 | 0.755766 | 3 | 0 | 3 |
| CRCP | MICALCL | 0.753018 | 3 | 0 | 3 |
| CRCP | MRPS9 | 0.750449 | 3 | 0 | 3 |
| CRCP | GPATCH4 | 0.749593 | 3 | 0 | 3 |
| CRCP | NEDD1 | 0.743139 | 3 | 0 | 3 |
| CRCP | TMEM106A | 0.735126 | 3 | 0 | 3 |
| CRCP | TRUB2 | 0.734374 | 3 | 0 | 3 |
| CRCP | ELOF1 | 0.729495 | 3 | 0 | 3 |
| CRCP | AKT1S1 | 0.722194 | 3 | 0 | 3 |
| CRCP | CEP89 | 0.720024 | 3 | 0 | 3 |
| CRCP | PKNOX1 | 0.713429 | 4 | 0 | 3 |
| CRCP | C3orf33 | 0.709189 | 4 | 0 | 3 |
| CRCP | PMF1 | 0.706141 | 3 | 0 | 3 |
| CRCP | ZNF558 | 0.703292 | 3 | 0 | 3 |
| CRCP | G2E3 | 0.701732 | 4 | 0 | 3 |
| CRCP | CCDC15 | 0.700725 | 4 | 0 | 4 |
For details and further investigation, click here
