| Full name: adipogenesis associated Mth938 domain containing | Alias Symbol: PTD015|FLJ21035|CK067 | ||
| Type: protein-coding gene | Cytoband: 11q14.1 | ||
| Entrez ID: 28971 | HGNC ID: HGNC:30205 | Ensembl Gene: ENSG00000087884 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of AAMDC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AAMDC | 28971 | 221599_at | -0.2490 | 0.8291 | |
| GSE20347 | AAMDC | 28971 | 221599_at | -0.3673 | 0.0283 | |
| GSE23400 | AAMDC | 28971 | 221599_at | -0.2581 | 0.0016 | |
| GSE26886 | AAMDC | 28971 | 221599_at | 0.3244 | 0.0885 | |
| GSE29001 | AAMDC | 28971 | 221599_at | -0.6129 | 0.0297 | |
| GSE38129 | AAMDC | 28971 | 221599_at | -0.7025 | 0.0021 | |
| GSE45670 | AAMDC | 28971 | 221599_at | -0.4496 | 0.0064 | |
| GSE63941 | AAMDC | 28971 | 221599_at | -1.5303 | 0.0189 | |
| GSE77861 | AAMDC | 28971 | 221599_at | -0.2911 | 0.0177 | |
| SRP007169 | AAMDC | 28971 | RNAseq | -0.5025 | 0.4540 | |
| SRP064894 | AAMDC | 28971 | RNAseq | 0.0132 | 0.9722 | |
| SRP133303 | AAMDC | 28971 | RNAseq | -0.5657 | 0.0059 | |
| SRP159526 | AAMDC | 28971 | RNAseq | -0.5339 | 0.0874 | |
| SRP193095 | AAMDC | 28971 | RNAseq | -0.6915 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Copy number change of AAMDC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AAMDC | 28971 | 5 | 10 | 15 | |
| GSE20123 | AAMDC | 28971 | 5 | 9 | 16 | |
| GSE43470 | AAMDC | 28971 | 3 | 5 | 35 | |
| GSE46452 | AAMDC | 28971 | 7 | 22 | 30 | |
| GSE47630 | AAMDC | 28971 | 4 | 17 | 19 | |
| GSE54993 | AAMDC | 28971 | 8 | 2 | 60 | |
| GSE54994 | AAMDC | 28971 | 6 | 17 | 30 | |
| GSE60625 | AAMDC | 28971 | 4 | 3 | 4 | |
| GSE74703 | AAMDC | 28971 | 2 | 4 | 30 | |
| GSE74704 | AAMDC | 28971 | 3 | 4 | 13 | |
| TCGA | AAMDC | 28971 | 18 | 32 | 46 |
Total number of gains: 65; Total number of losses: 125; Total Number of normals: 298.
Somatic mutations of AAMDC:
Generating mutation plots.
Highly correlated genes for AAMDC:
Showing top 20/261 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AAMDC | CEP57L1 | 0.718809 | 3 | 0 | 3 |
| AAMDC | MAP4 | 0.676863 | 4 | 0 | 4 |
| AAMDC | ZNF439 | 0.665008 | 3 | 0 | 3 |
| AAMDC | SETD3 | 0.66133 | 3 | 0 | 3 |
| AAMDC | PAXBP1-AS1 | 0.654264 | 3 | 0 | 3 |
| AAMDC | NPR2 | 0.652852 | 4 | 0 | 3 |
| AAMDC | DIXDC1 | 0.647371 | 5 | 0 | 4 |
| AAMDC | THRB | 0.646105 | 4 | 0 | 3 |
| AAMDC | HAND2-AS1 | 0.638336 | 5 | 0 | 4 |
| AAMDC | NLGN4X | 0.637424 | 3 | 0 | 3 |
| AAMDC | ACO1 | 0.634757 | 4 | 0 | 3 |
| AAMDC | TCEAL2 | 0.634718 | 6 | 0 | 4 |
| AAMDC | ACTN2 | 0.633245 | 4 | 0 | 3 |
| AAMDC | CHRDL1 | 0.63259 | 4 | 0 | 3 |
| AAMDC | NR3C2 | 0.630057 | 4 | 0 | 4 |
| AAMDC | BHMT2 | 0.628381 | 6 | 0 | 4 |
| AAMDC | FIG4 | 0.627247 | 3 | 0 | 3 |
| AAMDC | COL21A1 | 0.623258 | 3 | 0 | 3 |
| AAMDC | NPY | 0.61889 | 6 | 0 | 4 |
| AAMDC | ESRRG | 0.617663 | 4 | 0 | 3 |
For details and further investigation, click here
