| Full name: bromodomain and PHD finger containing 1 | Alias Symbol: BR140 | ||
| Type: protein-coding gene | Cytoband: 3p25.3 | ||
| Entrez ID: 7862 | HGNC ID: HGNC:14255 | Ensembl Gene: ENSG00000156983 | OMIM ID: 602410 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of BRPF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BRPF1 | 7862 | 204481_at | 0.3981 | 0.3251 | |
| GSE20347 | BRPF1 | 7862 | 204481_at | -0.0373 | 0.8175 | |
| GSE23400 | BRPF1 | 7862 | 204481_at | 0.0384 | 0.5039 | |
| GSE26886 | BRPF1 | 7862 | 204481_at | 0.3110 | 0.0526 | |
| GSE29001 | BRPF1 | 7862 | 204481_at | -0.1790 | 0.2663 | |
| GSE38129 | BRPF1 | 7862 | 204481_at | -0.1077 | 0.4237 | |
| GSE45670 | BRPF1 | 7862 | 204481_at | -0.1477 | 0.0915 | |
| GSE53622 | BRPF1 | 7862 | 98730 | -0.0130 | 0.8028 | |
| GSE53624 | BRPF1 | 7862 | 98730 | 0.0473 | 0.5389 | |
| GSE63941 | BRPF1 | 7862 | 204481_at | 0.1615 | 0.6946 | |
| GSE77861 | BRPF1 | 7862 | 204481_at | -0.0637 | 0.6274 | |
| GSE97050 | BRPF1 | 7862 | A_23_P250948 | -0.1216 | 0.5452 | |
| SRP007169 | BRPF1 | 7862 | RNAseq | 0.2607 | 0.6863 | |
| SRP008496 | BRPF1 | 7862 | RNAseq | 0.2756 | 0.5498 | |
| SRP064894 | BRPF1 | 7862 | RNAseq | -0.2163 | 0.2024 | |
| SRP133303 | BRPF1 | 7862 | RNAseq | -0.1412 | 0.4025 | |
| SRP159526 | BRPF1 | 7862 | RNAseq | -0.3378 | 0.1853 | |
| SRP193095 | BRPF1 | 7862 | RNAseq | -0.0044 | 0.9633 | |
| SRP219564 | BRPF1 | 7862 | RNAseq | -0.5812 | 0.0372 | |
| TCGA | BRPF1 | 7862 | RNAseq | -0.0713 | 0.1818 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BRPF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BRPF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BRPF1 | 7862 | 1 | 18 | 11 | |
| GSE20123 | BRPF1 | 7862 | 1 | 18 | 11 | |
| GSE43470 | BRPF1 | 7862 | 1 | 20 | 22 | |
| GSE46452 | BRPF1 | 7862 | 2 | 17 | 40 | |
| GSE47630 | BRPF1 | 7862 | 3 | 22 | 15 | |
| GSE54993 | BRPF1 | 7862 | 6 | 1 | 63 | |
| GSE54994 | BRPF1 | 7862 | 3 | 31 | 19 | |
| GSE60625 | BRPF1 | 7862 | 5 | 0 | 6 | |
| GSE74703 | BRPF1 | 7862 | 1 | 16 | 19 | |
| GSE74704 | BRPF1 | 7862 | 1 | 11 | 8 | |
| TCGA | BRPF1 | 7862 | 5 | 65 | 26 |
Total number of gains: 29; Total number of losses: 219; Total Number of normals: 240.
Somatic mutations of BRPF1:
Generating mutation plots.
Highly correlated genes for BRPF1:
Showing top 20/183 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BRPF1 | RBM42 | 0.744795 | 3 | 0 | 3 |
| BRPF1 | SGTA | 0.727924 | 3 | 0 | 3 |
| BRPF1 | TNFAIP8L1 | 0.720296 | 3 | 0 | 3 |
| BRPF1 | NOC4L | 0.713808 | 3 | 0 | 3 |
| BRPF1 | FLAD1 | 0.711439 | 3 | 0 | 3 |
| BRPF1 | TFR2 | 0.706892 | 3 | 0 | 3 |
| BRPF1 | POM121L12 | 0.694549 | 3 | 0 | 3 |
| BRPF1 | ZNF316 | 0.694387 | 3 | 0 | 3 |
| BRPF1 | FBRSL1 | 0.684963 | 4 | 0 | 3 |
| BRPF1 | FPGS | 0.680593 | 3 | 0 | 3 |
| BRPF1 | ZNF527 | 0.676903 | 3 | 0 | 3 |
| BRPF1 | FAM53A | 0.673008 | 3 | 0 | 3 |
| BRPF1 | CNOT3 | 0.670697 | 4 | 0 | 3 |
| BRPF1 | FBXO44 | 0.665503 | 4 | 0 | 4 |
| BRPF1 | EVX1 | 0.662111 | 4 | 0 | 4 |
| BRPF1 | PRDM13 | 0.658209 | 4 | 0 | 3 |
| BRPF1 | MYO1C | 0.65635 | 3 | 0 | 3 |
| BRPF1 | FAM181A | 0.655347 | 4 | 0 | 4 |
| BRPF1 | SPRED3 | 0.653863 | 4 | 0 | 4 |
| BRPF1 | DOHH | 0.653333 | 4 | 0 | 4 |
For details and further investigation, click here
