| Full name: ADP ribosylation factor interacting protein 1 | Alias Symbol: HSU52521 | ||
| Type: protein-coding gene | Cytoband: 4q31.3 | ||
| Entrez ID: 27236 | HGNC ID: HGNC:21496 | Ensembl Gene: ENSG00000164144 | OMIM ID: 605928 |
| Drug and gene relationship at DGIdb | |||
Expression of ARFIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARFIP1 | 27236 | 218230_at | -0.3144 | 0.5650 | |
| GSE20347 | ARFIP1 | 27236 | 218230_at | -0.5915 | 0.0000 | |
| GSE23400 | ARFIP1 | 27236 | 218230_at | -0.1686 | 0.0142 | |
| GSE26886 | ARFIP1 | 27236 | 218230_at | -0.8776 | 0.0001 | |
| GSE29001 | ARFIP1 | 27236 | 218230_at | -0.3386 | 0.1037 | |
| GSE38129 | ARFIP1 | 27236 | 218230_at | -0.5094 | 0.0000 | |
| GSE45670 | ARFIP1 | 27236 | 218230_at | -0.1252 | 0.2910 | |
| GSE53622 | ARFIP1 | 27236 | 17690 | -0.5483 | 0.0000 | |
| GSE53624 | ARFIP1 | 27236 | 17690 | -0.6101 | 0.0000 | |
| GSE63941 | ARFIP1 | 27236 | 218230_at | -1.0329 | 0.3061 | |
| GSE77861 | ARFIP1 | 27236 | 218230_at | -0.4850 | 0.0238 | |
| GSE97050 | ARFIP1 | 27236 | A_24_P166094 | -0.1660 | 0.6312 | |
| SRP007169 | ARFIP1 | 27236 | RNAseq | -1.0244 | 0.0151 | |
| SRP008496 | ARFIP1 | 27236 | RNAseq | -1.0560 | 0.0000 | |
| SRP064894 | ARFIP1 | 27236 | RNAseq | -0.4099 | 0.0144 | |
| SRP133303 | ARFIP1 | 27236 | RNAseq | 0.1318 | 0.4990 | |
| SRP159526 | ARFIP1 | 27236 | RNAseq | -0.4937 | 0.0073 | |
| SRP193095 | ARFIP1 | 27236 | RNAseq | -0.6862 | 0.0000 | |
| SRP219564 | ARFIP1 | 27236 | RNAseq | -0.5779 | 0.0420 | |
| TCGA | ARFIP1 | 27236 | RNAseq | -0.0924 | 0.0588 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ARFIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARFIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARFIP1 | 27236 | 0 | 14 | 16 | |
| GSE20123 | ARFIP1 | 27236 | 0 | 14 | 16 | |
| GSE43470 | ARFIP1 | 27236 | 0 | 14 | 29 | |
| GSE46452 | ARFIP1 | 27236 | 1 | 36 | 22 | |
| GSE47630 | ARFIP1 | 27236 | 0 | 23 | 17 | |
| GSE54993 | ARFIP1 | 27236 | 10 | 0 | 60 | |
| GSE54994 | ARFIP1 | 27236 | 1 | 13 | 39 | |
| GSE60625 | ARFIP1 | 27236 | 0 | 1 | 10 | |
| GSE74703 | ARFIP1 | 27236 | 0 | 12 | 24 | |
| GSE74704 | ARFIP1 | 27236 | 0 | 7 | 13 | |
| TCGA | ARFIP1 | 27236 | 10 | 37 | 49 |
Total number of gains: 22; Total number of losses: 171; Total Number of normals: 295.
Somatic mutations of ARFIP1:
Generating mutation plots.
Highly correlated genes for ARFIP1:
Showing top 20/1373 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARFIP1 | DLG1 | 0.826448 | 3 | 0 | 3 |
| ARFIP1 | EGLN1 | 0.767103 | 3 | 0 | 3 |
| ARFIP1 | PITHD1 | 0.766223 | 6 | 0 | 6 |
| ARFIP1 | ICK | 0.764996 | 3 | 0 | 3 |
| ARFIP1 | TP53RK | 0.756658 | 3 | 0 | 3 |
| ARFIP1 | AKAP17A | 0.751229 | 3 | 0 | 3 |
| ARFIP1 | RHBDD1 | 0.747276 | 3 | 0 | 3 |
| ARFIP1 | SLC44A2 | 0.744939 | 4 | 0 | 4 |
| ARFIP1 | SCOC | 0.730707 | 8 | 0 | 8 |
| ARFIP1 | ABHD12 | 0.729036 | 3 | 0 | 3 |
| ARFIP1 | PPP1R11 | 0.726949 | 3 | 0 | 3 |
| ARFIP1 | NACA2 | 0.726859 | 3 | 0 | 3 |
| ARFIP1 | LAMTOR3 | 0.72484 | 11 | 0 | 11 |
| ARFIP1 | PSENEN | 0.721405 | 4 | 0 | 4 |
| ARFIP1 | TXLNA | 0.71785 | 3 | 0 | 3 |
| ARFIP1 | SCP2 | 0.7112 | 12 | 0 | 11 |
| ARFIP1 | ZNF207 | 0.709652 | 5 | 0 | 4 |
| ARFIP1 | FBXO8 | 0.7085 | 8 | 0 | 8 |
| ARFIP1 | SMURF1 | 0.708058 | 3 | 0 | 3 |
| ARFIP1 | ZNF35 | 0.706352 | 3 | 0 | 3 |
For details and further investigation, click here
