| Full name: family with sequence similarity 107 member B | Alias Symbol: FLJ45505|MGC11034|HITS | ||
| Type: protein-coding gene | Cytoband: 10p13 | ||
| Entrez ID: 83641 | HGNC ID: HGNC:23726 | Ensembl Gene: ENSG00000065809 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM107B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM107B | 83641 | 223059_s_at | -0.0622 | 0.9518 | |
| GSE26886 | FAM107B | 83641 | 223059_s_at | -1.1223 | 0.0055 | |
| GSE45670 | FAM107B | 83641 | 223059_s_at | -0.4008 | 0.1615 | |
| GSE53622 | FAM107B | 83641 | 111714 | -0.6626 | 0.0000 | |
| GSE53624 | FAM107B | 83641 | 111714 | -0.8225 | 0.0000 | |
| GSE63941 | FAM107B | 83641 | 223059_s_at | -1.5111 | 0.3554 | |
| GSE77861 | FAM107B | 83641 | 223059_s_at | -0.4460 | 0.4302 | |
| GSE97050 | FAM107B | 83641 | A_23_P149975 | 0.5572 | 0.1817 | |
| SRP007169 | FAM107B | 83641 | RNAseq | -1.1805 | 0.0014 | |
| SRP008496 | FAM107B | 83641 | RNAseq | -1.4413 | 0.0000 | |
| SRP064894 | FAM107B | 83641 | RNAseq | -0.5669 | 0.0338 | |
| SRP133303 | FAM107B | 83641 | RNAseq | -0.2615 | 0.3289 | |
| SRP159526 | FAM107B | 83641 | RNAseq | -1.0512 | 0.0126 | |
| SRP193095 | FAM107B | 83641 | RNAseq | -1.1033 | 0.0002 | |
| SRP219564 | FAM107B | 83641 | RNAseq | -0.1609 | 0.7411 | |
| TCGA | FAM107B | 83641 | RNAseq | -0.6865 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by FAM107B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM107B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM107B | 83641 | 3 | 9 | 18 | |
| GSE20123 | FAM107B | 83641 | 3 | 7 | 20 | |
| GSE43470 | FAM107B | 83641 | 3 | 5 | 35 | |
| GSE46452 | FAM107B | 83641 | 1 | 14 | 44 | |
| GSE47630 | FAM107B | 83641 | 5 | 15 | 20 | |
| GSE54993 | FAM107B | 83641 | 10 | 0 | 60 | |
| GSE54994 | FAM107B | 83641 | 4 | 9 | 40 | |
| GSE60625 | FAM107B | 83641 | 0 | 0 | 11 | |
| GSE74703 | FAM107B | 83641 | 2 | 3 | 31 | |
| GSE74704 | FAM107B | 83641 | 0 | 6 | 14 | |
| TCGA | FAM107B | 83641 | 20 | 25 | 51 |
Total number of gains: 51; Total number of losses: 93; Total Number of normals: 344.
Somatic mutations of FAM107B:
Generating mutation plots.
Highly correlated genes for FAM107B:
Showing top 20/305 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM107B | ABHD12 | 0.788544 | 3 | 0 | 3 |
| FAM107B | SLITRK6 | 0.783164 | 3 | 0 | 3 |
| FAM107B | STK17B | 0.728853 | 3 | 0 | 3 |
| FAM107B | PLAA | 0.718676 | 3 | 0 | 3 |
| FAM107B | SDC4 | 0.707005 | 3 | 0 | 3 |
| FAM107B | PIP4K2A | 0.706496 | 3 | 0 | 3 |
| FAM107B | LRP11 | 0.697114 | 3 | 0 | 3 |
| FAM107B | CLCC1 | 0.688895 | 3 | 0 | 3 |
| FAM107B | APOL6 | 0.687853 | 3 | 0 | 3 |
| FAM107B | LIPT1 | 0.686774 | 3 | 0 | 3 |
| FAM107B | IRAK2 | 0.686234 | 3 | 0 | 3 |
| FAM107B | SMC5 | 0.682671 | 3 | 0 | 3 |
| FAM107B | LSP1 | 0.671525 | 3 | 0 | 3 |
| FAM107B | KLHDC10 | 0.671117 | 3 | 0 | 3 |
| FAM107B | SEC11C | 0.668762 | 5 | 0 | 5 |
| FAM107B | RNF213 | 0.668048 | 3 | 0 | 3 |
| FAM107B | DCAF12 | 0.663918 | 3 | 0 | 3 |
| FAM107B | SLC1A3 | 0.663229 | 4 | 0 | 3 |
| FAM107B | SEC23B | 0.652031 | 3 | 0 | 3 |
| FAM107B | EYA3 | 0.647436 | 5 | 0 | 5 |
For details and further investigation, click here
