| Full name: Fc fragment of IgG receptor and transporter | Alias Symbol: FCRN|alpha-chain | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 2217 | HGNC ID: HGNC:3621 | Ensembl Gene: ENSG00000104870 | OMIM ID: 601437 |
| Drug and gene relationship at DGIdb | |||
Expression of FCGRT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FCGRT | 2217 | 218831_s_at | -0.2670 | 0.5614 | |
| GSE20347 | FCGRT | 2217 | 218831_s_at | 0.2425 | 0.0944 | |
| GSE23400 | FCGRT | 2217 | 218831_s_at | 0.0667 | 0.4146 | |
| GSE26886 | FCGRT | 2217 | 218831_s_at | 0.3177 | 0.3455 | |
| GSE29001 | FCGRT | 2217 | 218831_s_at | 0.2824 | 0.3274 | |
| GSE38129 | FCGRT | 2217 | 218831_s_at | 0.0354 | 0.8960 | |
| GSE45670 | FCGRT | 2217 | 218831_s_at | -0.8077 | 0.0003 | |
| GSE53622 | FCGRT | 2217 | 76771 | -0.1596 | 0.2169 | |
| GSE53624 | FCGRT | 2217 | 76771 | 0.1484 | 0.0852 | |
| GSE63941 | FCGRT | 2217 | 218831_s_at | -1.6223 | 0.0243 | |
| GSE77861 | FCGRT | 2217 | 218831_s_at | 0.0630 | 0.6128 | |
| GSE97050 | FCGRT | 2217 | A_23_P55936 | 0.0082 | 0.9808 | |
| SRP007169 | FCGRT | 2217 | RNAseq | 0.4417 | 0.3780 | |
| SRP008496 | FCGRT | 2217 | RNAseq | 0.5734 | 0.0823 | |
| SRP064894 | FCGRT | 2217 | RNAseq | 0.4387 | 0.2745 | |
| SRP133303 | FCGRT | 2217 | RNAseq | -0.4336 | 0.0913 | |
| SRP159526 | FCGRT | 2217 | RNAseq | 0.2776 | 0.2996 | |
| SRP193095 | FCGRT | 2217 | RNAseq | -0.3732 | 0.2963 | |
| SRP219564 | FCGRT | 2217 | RNAseq | 0.6175 | 0.2682 | |
| TCGA | FCGRT | 2217 | RNAseq | -0.3221 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FCGRT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FCGRT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FCGRT | 2217 | 4 | 4 | 22 | |
| GSE20123 | FCGRT | 2217 | 4 | 3 | 23 | |
| GSE43470 | FCGRT | 2217 | 4 | 11 | 28 | |
| GSE46452 | FCGRT | 2217 | 45 | 1 | 13 | |
| GSE47630 | FCGRT | 2217 | 10 | 6 | 24 | |
| GSE54993 | FCGRT | 2217 | 17 | 4 | 49 | |
| GSE54994 | FCGRT | 2217 | 4 | 14 | 35 | |
| GSE60625 | FCGRT | 2217 | 9 | 0 | 2 | |
| GSE74703 | FCGRT | 2217 | 4 | 7 | 25 | |
| GSE74704 | FCGRT | 2217 | 4 | 1 | 15 | |
| TCGA | FCGRT | 2217 | 14 | 19 | 63 |
Total number of gains: 119; Total number of losses: 70; Total Number of normals: 299.
Somatic mutations of FCGRT:
Generating mutation plots.
Highly correlated genes for FCGRT:
Showing top 20/1066 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FCGRT | GPIHBP1 | 0.768889 | 3 | 0 | 3 |
| FCGRT | MOB3A | 0.756111 | 3 | 0 | 3 |
| FCGRT | FIBIN | 0.747361 | 4 | 0 | 4 |
| FCGRT | RNASE1 | 0.742433 | 9 | 0 | 9 |
| FCGRT | CNRIP1 | 0.736709 | 6 | 0 | 5 |
| FCGRT | FXYD6 | 0.730462 | 9 | 0 | 9 |
| FCGRT | XPC | 0.725501 | 3 | 0 | 3 |
| FCGRT | SSH1 | 0.722702 | 3 | 0 | 3 |
| FCGRT | ABHD2 | 0.720319 | 3 | 0 | 3 |
| FCGRT | EMCN | 0.718258 | 5 | 0 | 4 |
| FCGRT | GNG2 | 0.716106 | 5 | 0 | 4 |
| FCGRT | BHLHE22 | 0.709446 | 5 | 0 | 5 |
| FCGRT | C19orf38 | 0.70611 | 3 | 0 | 3 |
| FCGRT | ZNF512 | 0.701683 | 4 | 0 | 3 |
| FCGRT | SCARF1 | 0.699237 | 3 | 0 | 3 |
| FCGRT | DPYSL2 | 0.69832 | 9 | 0 | 8 |
| FCGRT | MEOX2 | 0.697383 | 7 | 0 | 5 |
| FCGRT | POLK | 0.690005 | 3 | 0 | 3 |
| FCGRT | SGCE | 0.688539 | 10 | 0 | 9 |
| FCGRT | PDGFB | 0.687667 | 3 | 0 | 3 |
For details and further investigation, click here
