| Full name: ankyrin repeat and BTB domain containing 2 | Alias Symbol: DKFZP586C1619|BTBD22|ABTB2A | ||
| Type: protein-coding gene | Cytoband: 11p13 | ||
| Entrez ID: 25841 | HGNC ID: HGNC:23842 | Ensembl Gene: ENSG00000166016 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ABTB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABTB2 | 25841 | 213497_at | 0.0042 | 0.9931 | |
| GSE20347 | ABTB2 | 25841 | 213497_at | 0.0168 | 0.9353 | |
| GSE23400 | ABTB2 | 25841 | 213497_at | -0.2439 | 0.0000 | |
| GSE26886 | ABTB2 | 25841 | 213497_at | -0.7584 | 0.0516 | |
| GSE29001 | ABTB2 | 25841 | 213497_at | -0.1165 | 0.8088 | |
| GSE38129 | ABTB2 | 25841 | 213497_at | -0.1607 | 0.2452 | |
| GSE45670 | ABTB2 | 25841 | 213497_at | -0.0240 | 0.9274 | |
| GSE53622 | ABTB2 | 25841 | 14451 | 0.1017 | 0.5500 | |
| GSE53624 | ABTB2 | 25841 | 14451 | -0.4092 | 0.0000 | |
| GSE63941 | ABTB2 | 25841 | 213497_at | -0.3084 | 0.3854 | |
| GSE77861 | ABTB2 | 25841 | 213497_at | -0.1569 | 0.1892 | |
| GSE97050 | ABTB2 | 25841 | A_23_P356616 | 0.1913 | 0.4410 | |
| SRP007169 | ABTB2 | 25841 | RNAseq | -1.8274 | 0.0202 | |
| SRP008496 | ABTB2 | 25841 | RNAseq | -2.1705 | 0.0000 | |
| SRP064894 | ABTB2 | 25841 | RNAseq | -1.0871 | 0.0002 | |
| SRP133303 | ABTB2 | 25841 | RNAseq | 0.2139 | 0.4659 | |
| SRP159526 | ABTB2 | 25841 | RNAseq | 1.4861 | 0.0570 | |
| SRP193095 | ABTB2 | 25841 | RNAseq | -0.6303 | 0.0091 | |
| SRP219564 | ABTB2 | 25841 | RNAseq | -0.4694 | 0.2556 | |
| TCGA | ABTB2 | 25841 | RNAseq | -0.1256 | 0.3636 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ABTB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABTB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABTB2 | 25841 | 1 | 6 | 23 | |
| GSE20123 | ABTB2 | 25841 | 1 | 5 | 24 | |
| GSE43470 | ABTB2 | 25841 | 3 | 4 | 36 | |
| GSE46452 | ABTB2 | 25841 | 7 | 5 | 47 | |
| GSE47630 | ABTB2 | 25841 | 3 | 10 | 27 | |
| GSE54993 | ABTB2 | 25841 | 3 | 2 | 65 | |
| GSE54994 | ABTB2 | 25841 | 3 | 10 | 40 | |
| GSE60625 | ABTB2 | 25841 | 0 | 0 | 11 | |
| GSE74703 | ABTB2 | 25841 | 3 | 2 | 31 | |
| GSE74704 | ABTB2 | 25841 | 0 | 3 | 17 | |
| TCGA | ABTB2 | 25841 | 14 | 24 | 58 |
Total number of gains: 38; Total number of losses: 71; Total Number of normals: 379.
Somatic mutations of ABTB2:
Generating mutation plots.
Highly correlated genes for ABTB2:
Showing top 20/24 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABTB2 | FAM209B | 0.641683 | 3 | 0 | 3 |
| ABTB2 | SEZ6 | 0.610991 | 3 | 0 | 3 |
| ABTB2 | FSD1 | 0.605387 | 4 | 0 | 3 |
| ABTB2 | OBP2A | 0.6017 | 5 | 0 | 4 |
| ABTB2 | SOX10 | 0.595127 | 4 | 0 | 3 |
| ABTB2 | HSPA1L | 0.581145 | 4 | 0 | 4 |
| ABTB2 | TP53I3 | 0.581126 | 4 | 0 | 3 |
| ABTB2 | CSN3 | 0.577267 | 3 | 0 | 3 |
| ABTB2 | HAND2-AS1 | 0.572547 | 4 | 0 | 3 |
| ABTB2 | SOBP | 0.545653 | 4 | 0 | 3 |
| ABTB2 | ALDH3B1 | 0.544444 | 4 | 0 | 3 |
| ABTB2 | ATRNL1 | 0.54272 | 5 | 0 | 3 |
| ABTB2 | GDPD3 | 0.540245 | 3 | 0 | 3 |
| ABTB2 | EIF4EBP2 | 0.522066 | 5 | 0 | 3 |
| ABTB2 | RAPGEF3 | 0.520112 | 4 | 0 | 3 |
| ABTB2 | ACAA1 | 0.51402 | 4 | 0 | 3 |
| ABTB2 | EHD3 | 0.510574 | 4 | 0 | 3 |
| ABTB2 | OR10H2 | 0.507603 | 4 | 0 | 3 |
| ABTB2 | WBP2 | 0.506744 | 4 | 0 | 3 |
| ABTB2 | TNIP1 | 0.505097 | 6 | 0 | 3 |
For details and further investigation, click here
