| Full name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 | Alias Symbol: KIAA1716 | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 116983 | HGNC ID: HGNC:16754 | Ensembl Gene: ENSG00000131584 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ACAP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACAP3 | 116983 | 225529_at | 0.0566 | 0.9200 | |
| GSE26886 | ACAP3 | 116983 | 225529_at | -0.4819 | 0.1082 | |
| GSE45670 | ACAP3 | 116983 | 225529_at | -0.2201 | 0.1507 | |
| GSE53622 | ACAP3 | 116983 | 68196 | -0.4762 | 0.0000 | |
| GSE53624 | ACAP3 | 116983 | 68196 | -0.3600 | 0.0000 | |
| GSE63941 | ACAP3 | 116983 | 225529_at | 0.1975 | 0.7233 | |
| GSE77861 | ACAP3 | 116983 | 225529_at | -0.2214 | 0.5525 | |
| GSE97050 | ACAP3 | 116983 | A_33_P3398564 | -0.0077 | 0.9785 | |
| SRP007169 | ACAP3 | 116983 | RNAseq | -1.2856 | 0.0060 | |
| SRP008496 | ACAP3 | 116983 | RNAseq | -0.8345 | 0.0166 | |
| SRP064894 | ACAP3 | 116983 | RNAseq | -0.0682 | 0.7095 | |
| SRP133303 | ACAP3 | 116983 | RNAseq | -0.5805 | 0.0023 | |
| SRP159526 | ACAP3 | 116983 | RNAseq | -0.4675 | 0.1541 | |
| SRP193095 | ACAP3 | 116983 | RNAseq | -0.0822 | 0.6479 | |
| SRP219564 | ACAP3 | 116983 | RNAseq | -0.3950 | 0.2119 | |
| TCGA | ACAP3 | 116983 | RNAseq | -0.0384 | 0.5351 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ACAP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACAP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACAP3 | 116983 | 3 | 7 | 20 | |
| GSE20123 | ACAP3 | 116983 | 3 | 6 | 21 | |
| GSE43470 | ACAP3 | 116983 | 3 | 5 | 35 | |
| GSE46452 | ACAP3 | 116983 | 7 | 1 | 51 | |
| GSE47630 | ACAP3 | 116983 | 8 | 4 | 28 | |
| GSE54993 | ACAP3 | 116983 | 2 | 2 | 66 | |
| GSE54994 | ACAP3 | 116983 | 15 | 2 | 36 | |
| GSE60625 | ACAP3 | 116983 | 0 | 0 | 11 | |
| GSE74703 | ACAP3 | 116983 | 3 | 3 | 30 | |
| GSE74704 | ACAP3 | 116983 | 3 | 0 | 17 | |
| TCGA | ACAP3 | 116983 | 14 | 20 | 62 |
Total number of gains: 61; Total number of losses: 50; Total Number of normals: 377.
Somatic mutations of ACAP3:
Generating mutation plots.
Highly correlated genes for ACAP3:
Showing top 20/130 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACAP3 | RNF167 | 0.696433 | 4 | 0 | 3 |
| ACAP3 | CEP104 | 0.685019 | 3 | 0 | 3 |
| ACAP3 | PICK1 | 0.6637 | 3 | 0 | 3 |
| ACAP3 | SLC22A11 | 0.661575 | 3 | 0 | 3 |
| ACAP3 | C11orf86 | 0.659371 | 3 | 0 | 3 |
| ACAP3 | RGS12 | 0.654701 | 6 | 0 | 4 |
| ACAP3 | CNGB1 | 0.65326 | 3 | 0 | 3 |
| ACAP3 | BCKDHA | 0.645952 | 3 | 0 | 3 |
| ACAP3 | OTOF | 0.635762 | 3 | 0 | 3 |
| ACAP3 | TMUB1 | 0.634894 | 4 | 0 | 3 |
| ACAP3 | MROH6 | 0.624642 | 4 | 0 | 4 |
| ACAP3 | RDH13 | 0.622682 | 5 | 0 | 4 |
| ACAP3 | LTB4R | 0.621654 | 4 | 0 | 3 |
| ACAP3 | GGT6 | 0.619942 | 4 | 0 | 4 |
| ACAP3 | BEAN1 | 0.619393 | 4 | 0 | 3 |
| ACAP3 | CPNE6 | 0.617408 | 4 | 0 | 3 |
| ACAP3 | MFSD2B | 0.616533 | 3 | 0 | 3 |
| ACAP3 | FAM214B | 0.612974 | 6 | 0 | 5 |
| ACAP3 | ATP6V0A1 | 0.610993 | 4 | 0 | 3 |
| ACAP3 | EPN2 | 0.61099 | 3 | 0 | 3 |
For details and further investigation, click here
