| Full name: maestro heat like repeat family member 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 642475 | HGNC ID: HGNC:27814 | Ensembl Gene: ENSG00000204839 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MROH6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MROH6 | 642475 | 227672_at | -0.1927 | 0.7329 | |
| GSE26886 | MROH6 | 642475 | 227672_at | -0.4757 | 0.0014 | |
| GSE45670 | MROH6 | 642475 | 227672_at | -0.0731 | 0.7492 | |
| GSE53622 | MROH6 | 642475 | 11520 | -0.8065 | 0.0000 | |
| GSE53624 | MROH6 | 642475 | 11520 | -1.3674 | 0.0000 | |
| GSE63941 | MROH6 | 642475 | 227672_at | 0.1694 | 0.6685 | |
| GSE77861 | MROH6 | 642475 | 227672_at | -0.3727 | 0.1519 | |
| SRP007169 | MROH6 | 642475 | RNAseq | -3.7250 | 0.0000 | |
| SRP008496 | MROH6 | 642475 | RNAseq | -3.8256 | 0.0000 | |
| SRP064894 | MROH6 | 642475 | RNAseq | -1.1711 | 0.0014 | |
| SRP133303 | MROH6 | 642475 | RNAseq | -2.3574 | 0.0000 | |
| SRP159526 | MROH6 | 642475 | RNAseq | -2.2369 | 0.0000 | |
| SRP193095 | MROH6 | 642475 | RNAseq | -1.2619 | 0.0000 | |
| SRP219564 | MROH6 | 642475 | RNAseq | -0.8681 | 0.3270 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by MROH6 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MROH6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MROH6 | 642475 | 17 | 1 | 12 | |
| GSE20123 | MROH6 | 642475 | 17 | 1 | 12 | |
| GSE43470 | MROH6 | 642475 | 17 | 2 | 24 | |
| GSE46452 | MROH6 | 642475 | 27 | 0 | 32 | |
| GSE47630 | MROH6 | 642475 | 23 | 1 | 16 | |
| GSE54993 | MROH6 | 642475 | 0 | 25 | 45 | |
| GSE54994 | MROH6 | 642475 | 39 | 1 | 13 | |
| GSE60625 | MROH6 | 642475 | 3 | 4 | 4 | |
| GSE74703 | MROH6 | 642475 | 15 | 1 | 20 | |
| GSE74704 | MROH6 | 642475 | 10 | 0 | 10 | |
| TCGA | MROH6 | 642475 | 64 | 2 | 30 |
Total number of gains: 232; Total number of losses: 38; Total Number of normals: 218.
Somatic mutations of MROH6:
Generating mutation plots.
Highly correlated genes for MROH6:
Showing top 20/776 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MROH6 | OTOF | 0.740387 | 3 | 0 | 3 |
| MROH6 | KCNA7 | 0.73147 | 3 | 0 | 3 |
| MROH6 | PLEKHN1 | 0.724447 | 6 | 0 | 6 |
| MROH6 | UPB1 | 0.724275 | 3 | 0 | 3 |
| MROH6 | NBEAL2 | 0.723001 | 6 | 0 | 6 |
| MROH6 | TCL6 | 0.721974 | 3 | 0 | 3 |
| MROH6 | HES5 | 0.721703 | 3 | 0 | 3 |
| MROH6 | TMEM79 | 0.697257 | 6 | 0 | 5 |
| MROH6 | SCNN1B | 0.694021 | 6 | 0 | 5 |
| MROH6 | HMGB4 | 0.693829 | 3 | 0 | 3 |
| MROH6 | SH3GL1 | 0.693775 | 6 | 0 | 6 |
| MROH6 | SMIM5 | 0.690851 | 5 | 0 | 5 |
| MROH6 | C14orf180 | 0.688509 | 3 | 0 | 3 |
| MROH6 | C3orf20 | 0.687669 | 3 | 0 | 3 |
| MROH6 | EML3 | 0.686872 | 5 | 0 | 5 |
| MROH6 | KRT32 | 0.686861 | 4 | 0 | 4 |
| MROH6 | IQCF1 | 0.68455 | 3 | 0 | 3 |
| MROH6 | EPS8L2 | 0.680427 | 6 | 0 | 6 |
| MROH6 | ZBTB7B | 0.680358 | 5 | 0 | 5 |
| MROH6 | ATG9B | 0.678264 | 6 | 0 | 6 |
For details and further investigation, click here
