| Full name: adrenomedullin 5 (putative) | Alias Symbol: AM5 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 199800 | HGNC ID: HGNC:27293 | Ensembl Gene: ENSG00000224420 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ADM5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADM5 | 199800 | 232154_at | -0.3799 | 0.4054 | |
| GSE26886 | ADM5 | 199800 | 232154_at | -0.1239 | 0.3182 | |
| GSE45670 | ADM5 | 199800 | 232154_at | -0.1676 | 0.2603 | |
| GSE63941 | ADM5 | 199800 | 232154_at | 0.6759 | 0.0315 | |
| GSE77861 | ADM5 | 199800 | 232154_at | -0.1214 | 0.4849 | |
| SRP064894 | ADM5 | 199800 | RNAseq | 1.2637 | 0.0021 | |
| SRP133303 | ADM5 | 199800 | RNAseq | -0.7343 | 0.0501 | |
| SRP159526 | ADM5 | 199800 | RNAseq | -0.0121 | 0.9787 | |
| SRP219564 | ADM5 | 199800 | RNAseq | 0.0553 | 0.9353 |
Upregulated datasets: 1; Downregulated datasets: 0.
Copy number change of ADM5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADM5 | 199800 | 4 | 4 | 22 | |
| GSE20123 | ADM5 | 199800 | 4 | 3 | 23 | |
| GSE43470 | ADM5 | 199800 | 5 | 11 | 27 | |
| GSE46452 | ADM5 | 199800 | 45 | 1 | 13 | |
| GSE47630 | ADM5 | 199800 | 10 | 6 | 24 | |
| GSE54993 | ADM5 | 199800 | 17 | 4 | 49 | |
| GSE54994 | ADM5 | 199800 | 4 | 14 | 35 | |
| GSE60625 | ADM5 | 199800 | 9 | 0 | 2 | |
| GSE74703 | ADM5 | 199800 | 5 | 7 | 24 | |
| GSE74704 | ADM5 | 199800 | 4 | 1 | 15 | |
| TCGA | ADM5 | 199800 | 14 | 18 | 64 |
Total number of gains: 121; Total number of losses: 69; Total Number of normals: 298.
Somatic mutations of ADM5:
Generating mutation plots.
Highly correlated genes for ADM5:
Showing top 20/27 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADM5 | PPP2R1A | 0.723035 | 3 | 0 | 3 |
| ADM5 | CS | 0.695848 | 3 | 0 | 3 |
| ADM5 | FGF18 | 0.649714 | 3 | 0 | 3 |
| ADM5 | USP54 | 0.644934 | 3 | 0 | 3 |
| ADM5 | PRKAG1 | 0.630651 | 3 | 0 | 3 |
| ADM5 | B3GNTL1 | 0.625948 | 3 | 0 | 3 |
| ADM5 | SLC25A5-AS1 | 0.62361 | 3 | 0 | 3 |
| ADM5 | PPM1J | 0.620553 | 3 | 0 | 3 |
| ADM5 | DUSP13 | 0.613877 | 3 | 0 | 3 |
| ADM5 | NPR1 | 0.602803 | 4 | 0 | 3 |
| ADM5 | EPB42 | 0.594522 | 3 | 0 | 3 |
| ADM5 | RPL18 | 0.588932 | 4 | 0 | 3 |
| ADM5 | PRKAG2-AS1 | 0.588692 | 3 | 0 | 3 |
| ADM5 | CYP3A43 | 0.583293 | 3 | 0 | 3 |
| ADM5 | ATP2A1 | 0.575076 | 3 | 0 | 3 |
| ADM5 | RPS5 | 0.572339 | 4 | 0 | 3 |
| ADM5 | MUC3B | 0.563998 | 3 | 0 | 3 |
| ADM5 | RAB17 | 0.563322 | 3 | 0 | 3 |
| ADM5 | EPHA3 | 0.559877 | 3 | 0 | 3 |
| ADM5 | SPTBN4 | 0.555224 | 3 | 0 | 3 |
For details and further investigation, click here
