| Full name: ADP-ribose/CDP-alcohol diphosphatase, manganese dependent | Alias Symbol: MDS006 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 56985 | HGNC ID: HGNC:30925 | Ensembl Gene: ENSG00000170222 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ADPRM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADPRM | 56985 | 223401_at | -0.4840 | 0.3037 | |
| GSE20347 | ADPRM | 56985 | 220606_s_at | -0.0338 | 0.8612 | |
| GSE23400 | ADPRM | 56985 | 220606_s_at | -0.0059 | 0.8905 | |
| GSE26886 | ADPRM | 56985 | 223401_at | 0.7427 | 0.0000 | |
| GSE29001 | ADPRM | 56985 | 220606_s_at | -0.0150 | 0.9224 | |
| GSE38129 | ADPRM | 56985 | 220606_s_at | -0.0801 | 0.6901 | |
| GSE45670 | ADPRM | 56985 | 223401_at | -0.3104 | 0.0058 | |
| GSE53622 | ADPRM | 56985 | 59428 | -0.1792 | 0.0056 | |
| GSE53624 | ADPRM | 56985 | 59428 | -0.2664 | 0.0007 | |
| GSE63941 | ADPRM | 56985 | 223401_at | -0.5088 | 0.3386 | |
| GSE77861 | ADPRM | 56985 | 223401_at | 0.0939 | 0.4586 | |
| SRP007169 | ADPRM | 56985 | RNAseq | -0.8803 | 0.0690 | |
| SRP008496 | ADPRM | 56985 | RNAseq | -0.6160 | 0.0553 | |
| SRP064894 | ADPRM | 56985 | RNAseq | 0.2683 | 0.2051 | |
| SRP133303 | ADPRM | 56985 | RNAseq | -0.3571 | 0.0282 | |
| SRP159526 | ADPRM | 56985 | RNAseq | -0.4847 | 0.1047 | |
| SRP193095 | ADPRM | 56985 | RNAseq | -0.4286 | 0.0009 | |
| SRP219564 | ADPRM | 56985 | RNAseq | -0.1613 | 0.6251 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ADPRM expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ADPRM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADPRM | 56985 | 3 | 4 | 23 | |
| GSE20123 | ADPRM | 56985 | 3 | 5 | 22 | |
| GSE43470 | ADPRM | 56985 | 2 | 5 | 36 | |
| GSE46452 | ADPRM | 56985 | 34 | 1 | 24 | |
| GSE47630 | ADPRM | 56985 | 7 | 1 | 32 | |
| GSE54993 | ADPRM | 56985 | 3 | 4 | 63 | |
| GSE54994 | ADPRM | 56985 | 5 | 7 | 41 | |
| GSE60625 | ADPRM | 56985 | 4 | 0 | 7 | |
| GSE74703 | ADPRM | 56985 | 2 | 3 | 31 | |
| GSE74704 | ADPRM | 56985 | 2 | 2 | 16 | |
| TCGA | ADPRM | 56985 | 18 | 20 | 58 |
Total number of gains: 83; Total number of losses: 52; Total Number of normals: 353.
Somatic mutations of ADPRM:
Generating mutation plots.
Highly correlated genes for ADPRM:
Showing top 20/81 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADPRM | PHF11 | 0.663692 | 3 | 0 | 3 |
| ADPRM | CMYA5 | 0.656231 | 3 | 0 | 3 |
| ADPRM | CPB2 | 0.642096 | 3 | 0 | 3 |
| ADPRM | PELO | 0.633411 | 4 | 0 | 4 |
| ADPRM | GFRA3 | 0.622622 | 4 | 0 | 3 |
| ADPRM | ITFG1 | 0.622218 | 3 | 0 | 3 |
| ADPRM | RPL22 | 0.604132 | 4 | 0 | 3 |
| ADPRM | HINT1 | 0.601349 | 4 | 0 | 3 |
| ADPRM | DNAJC18 | 0.600313 | 3 | 0 | 3 |
| ADPRM | MLLT10 | 0.599396 | 5 | 0 | 3 |
| ADPRM | GABRA2 | 0.596116 | 3 | 0 | 3 |
| ADPRM | PLN | 0.593782 | 4 | 0 | 3 |
| ADPRM | PCLO | 0.593436 | 3 | 0 | 3 |
| ADPRM | GTF2A1L | 0.593426 | 3 | 0 | 3 |
| ADPRM | STMN3 | 0.592318 | 3 | 0 | 3 |
| ADPRM | NIT1 | 0.586568 | 4 | 0 | 3 |
| ADPRM | ANAPC10 | 0.582691 | 5 | 0 | 3 |
| ADPRM | PHF3 | 0.579867 | 6 | 0 | 4 |
| ADPRM | ARHGAP29 | 0.576748 | 4 | 0 | 3 |
| ADPRM | EID2 | 0.576056 | 3 | 0 | 3 |
For details and further investigation, click here
